MSR1

 

Full name: macrophage scavenger receptor 1 Alias Symbol: SCARA1|CD204|SR-AI|SR-AII|SR-AIII|SR-A
Type: protein-coding gene Cytoband: 8p22
Entrez ID: 4481 HGNC ID: HGNC:7376 Ensembl Gene: ENSG00000038945 OMIM ID: 153622
Drug and gene relationship at DGIdb

 

Expression of MSR1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 MSR1 4481 214770_at 0.4212 0.6721
GSE20347 MSR1 4481 211887_x_at 0.0592 0.4372
GSE23400 MSR1 4481 211887_x_at 0.1008 0.0092
GSE26886 MSR1 4481 211887_x_at 0.0642 0.5981
GSE29001 MSR1 4481 208423_s_at 0.0414 0.7412
GSE38129 MSR1 4481 214770_at 0.7284 0.0126
GSE45670 MSR1 4481 214770_at -0.4169 0.3193
GSE53622 MSR1 4481 6196 1.0186 0.0000
GSE53624 MSR1 4481 6196 0.6185 0.0000
GSE63941 MSR1 4481 211887_x_at 0.1359 0.4716
GSE77861 MSR1 4481 211887_x_at 0.0368 0.7378
GSE97050 MSR1 4481 A_33_P3379326 0.4882 0.2460
SRP007169 MSR1 4481 RNAseq 5.1542 0.0000
SRP008496 MSR1 4481 RNAseq 5.3204 0.0000
SRP064894 MSR1 4481 RNAseq 2.4919 0.0000
SRP133303 MSR1 4481 RNAseq 2.1953 0.0000
SRP159526 MSR1 4481 RNAseq 2.3618 0.0005
SRP193095 MSR1 4481 RNAseq 2.2448 0.0000
SRP219564 MSR1 4481 RNAseq 2.3282 0.0098
TCGA MSR1 4481 RNAseq 0.7067 0.0001

Upregulated datasets: 8; Downregulated datasets: 0.  

 

Survival by MSR1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of MSR1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 MSR1 4481 4 11 15
GSE20123 MSR1 4481 4 11 15
GSE43470 MSR1 4481 4 8 31
GSE46452 MSR1 4481 13 14 32
GSE47630 MSR1 4481 10 8 22
GSE54993 MSR1 4481 3 13 54
GSE54994 MSR1 4481 8 18 27
GSE60625 MSR1 4481 3 0 8
GSE74703 MSR1 4481 4 7 25
GSE74704 MSR1 4481 3 7 10
TCGA MSR1 4481 14 40 42

Total number of gains: 70; Total number of losses: 137; Total Number of normals: 281.  

 

Somatic mutations of MSR1:

 

Generating mutation plots.

 

Highly correlated genes for MSR1:

 

Showing top 20/115 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
MSR1BMF0.735227404
MSR1ACSF30.714589303
MSR1PCSK1N0.706229403
MSR1FMNL10.703623505
MSR1LYG10.68977303
MSR1ADORA30.687111403
MSR1CCL270.683619303
MSR1ZMYND150.679745303
MSR1HTRA40.678247303
MSR1GPN20.67804303
MSR1LTC4S0.668212403
MSR1NLRP50.665155303
MSR1TEX13B0.663333303
MSR1PPM1J0.663314303
MSR1CMTM70.661457303
MSR1MMP23B0.660599303
MSR1HOTAIR0.656687303
MSR1PSMB90.65157403
MSR1FPR30.651314706
MSR1NAT140.643337505

For details and further investigation, click here