A PHP Error was encountered

Severity: Warning

Message: exec(): Unable to fork [Rscript361 /data/webapp/var/www/html/ESCCdb/application/scripts/R/getGeneSurvival_GSE.R FAM78A /data/webapp/var/www/html/ESCCdb/application/scripts/R/GSE53624_EXP_survival.RData application/survivalPlots/GSE53624]

Filename: controllers/Result_pages.php

Line Number: 123

Backtrace:

File: /data/webapp/var/www/html/ESCCdb/application/controllers/Result_pages.php
Line: 123
Function: exec

File: /data/webapp/var/www/html/ESCCdb/application/controllers/Result_pages.php
Line: 387
Function: drawSurvPlot

File: /data/webapp/var/www/html/ESCCdb/index.php
Line: 315
Function: require_once

Multi-Omics Database of ESCC

 

FAM78A

 

Full name: family with sequence similarity 78 member A Alias Symbol: FLJ00024
Type: protein-coding gene Cytoband: 9q34.13
Entrez ID: 286336 HGNC ID: HGNC:25465 Ensembl Gene: ENSG00000126882 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of FAM78A:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 FAM78A 286336 227002_at 0.4141 0.5334
GSE26886 FAM78A 286336 227002_at -0.0018 0.9928
GSE45670 FAM78A 286336 227002_at -0.0602 0.7501
GSE63941 FAM78A 286336 227002_at 0.5445 0.2629
GSE77861 FAM78A 286336 227002_at -0.1362 0.4596
GSE97050 FAM78A 286336 A_23_P314250 0.3659 0.1675
SRP007169 FAM78A 286336 RNAseq 1.6927 0.0716
SRP064894 FAM78A 286336 RNAseq 0.9337 0.0017
SRP133303 FAM78A 286336 RNAseq -0.0900 0.6271
SRP159526 FAM78A 286336 RNAseq -0.6703 0.3343
SRP193095 FAM78A 286336 RNAseq 0.2796 0.2005
SRP219564 FAM78A 286336 RNAseq 0.6781 0.0451
TCGA FAM78A 286336 RNAseq 0.0866 0.5285

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by FAM78A expression:

 

TCGA

 

Note: Click image to view full size file.  


Copy number change of FAM78A:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 FAM78A 286336 6 9 15
GSE20123 FAM78A 286336 6 9 15
GSE43470 FAM78A 286336 5 7 31
GSE46452 FAM78A 286336 6 13 40
GSE47630 FAM78A 286336 3 16 21
GSE54993 FAM78A 286336 3 3 64
GSE54994 FAM78A 286336 12 9 32
GSE60625 FAM78A 286336 0 0 11
GSE74703 FAM78A 286336 5 5 26
GSE74704 FAM78A 286336 3 7 10
TCGA FAM78A 286336 27 26 43

Total number of gains: 76; Total number of losses: 104; Total Number of normals: 308.  


 

Somatic mutations of FAM78A:

 

Generating mutation plots.

 

Highly correlated genes for FAM78A:

 

Showing top 20/137 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
FAM78ATRAT10.782039303
FAM78ACYTIP0.755981303
FAM78ASPOCK20.746802404
FAM78ARNASE60.745528303
FAM78ALY860.744718303
FAM78AAKNA0.734478403
FAM78ASNX200.725003403
FAM78ASUSD30.715581303
FAM78ABCL2L110.715198303
FAM78AIL2RB0.706611404
FAM78ATBC1D10C0.704038504
FAM78AARHGAP250.702359303
FAM78ACD480.696974504
FAM78AITGA40.696058303
FAM78AACSF30.695569303
FAM78ACD300C0.694606303
FAM78ALST10.693575404
FAM78AIL10RA0.686565403
FAM78AABI30.683207504
FAM78ATNFAIP8L20.682688303

For details and further investigation, click here