| Full name: actin related protein 3C | Alias Symbol: ARP11 | ||
| Type: protein-coding gene | Cytoband: 7q36.1 | ||
| Entrez ID: 653857 | HGNC ID: HGNC:37282 | Ensembl Gene: ENSG00000106526 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of ACTR3C:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ACTR3C | 653857 | 223874_at | -0.7457 | 0.1913 | |
| GSE26886 | ACTR3C | 653857 | 223874_at | -1.0849 | 0.0031 | |
| GSE45670 | ACTR3C | 653857 | 223874_at | -0.2942 | 0.2951 | |
| GSE53622 | ACTR3C | 653857 | 9770 | -0.0848 | 0.5500 | |
| GSE53624 | ACTR3C | 653857 | 44833 | -0.2288 | 0.0034 | |
| GSE63941 | ACTR3C | 653857 | 223874_at | 0.1697 | 0.8202 | |
| GSE77861 | ACTR3C | 653857 | 223874_at | -0.9868 | 0.0025 | |
| GSE97050 | ACTR3C | 653857 | A_33_P3333554 | 0.2473 | 0.5129 | |
| SRP007169 | ACTR3C | 653857 | RNAseq | -1.5664 | 0.0135 | |
| SRP008496 | ACTR3C | 653857 | RNAseq | -0.9834 | 0.0187 | |
| SRP064894 | ACTR3C | 653857 | RNAseq | -0.5670 | 0.0159 | |
| SRP133303 | ACTR3C | 653857 | RNAseq | -0.5655 | 0.0026 | |
| SRP159526 | ACTR3C | 653857 | RNAseq | -0.6002 | 0.0103 | |
| SRP193095 | ACTR3C | 653857 | RNAseq | -0.7276 | 0.0000 | |
| SRP219564 | ACTR3C | 653857 | RNAseq | -0.8615 | 0.0876 | |
| TCGA | ACTR3C | 653857 | RNAseq | -0.3913 | 0.1180 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by ACTR3C expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ACTR3C:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ACTR3C | 653857 | 2 | 4 | 24 | |
| GSE20123 | ACTR3C | 653857 | 2 | 4 | 24 | |
| GSE43470 | ACTR3C | 653857 | 2 | 5 | 36 | |
| GSE46452 | ACTR3C | 653857 | 7 | 2 | 50 | |
| GSE47630 | ACTR3C | 653857 | 6 | 8 | 26 | |
| GSE54993 | ACTR3C | 653857 | 3 | 3 | 64 | |
| GSE54994 | ACTR3C | 653857 | 6 | 8 | 39 | |
| GSE60625 | ACTR3C | 653857 | 0 | 0 | 11 | |
| GSE74703 | ACTR3C | 653857 | 2 | 4 | 30 | |
| GSE74704 | ACTR3C | 653857 | 1 | 4 | 15 | |
| TCGA | ACTR3C | 653857 | 25 | 27 | 44 |
Total number of gains: 56; Total number of losses: 69; Total Number of normals: 363.
Somatic mutations of ACTR3C:
Generating mutation plots.
Highly correlated genes for ACTR3C:
Showing top 20/835 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ACTR3C | UCHL3 | 0.800391 | 3 | 0 | 3 |
| ACTR3C | TXNDC17 | 0.762109 | 3 | 0 | 3 |
| ACTR3C | TSTA3 | 0.737256 | 3 | 0 | 3 |
| ACTR3C | MYD88 | 0.731194 | 3 | 0 | 3 |
| ACTR3C | C2orf16 | 0.730493 | 3 | 0 | 3 |
| ACTR3C | EXOC1 | 0.725105 | 4 | 0 | 4 |
| ACTR3C | FAR1 | 0.725059 | 3 | 0 | 3 |
| ACTR3C | GOLGA4 | 0.720739 | 5 | 0 | 4 |
| ACTR3C | HPSE | 0.718287 | 3 | 0 | 3 |
| ACTR3C | ZNF416 | 0.717138 | 4 | 0 | 4 |
| ACTR3C | CD2AP | 0.716297 | 4 | 0 | 4 |
| ACTR3C | OSBPL10 | 0.713867 | 4 | 0 | 3 |
| ACTR3C | VSIG10L | 0.711913 | 4 | 0 | 4 |
| ACTR3C | ACAA1 | 0.70856 | 5 | 0 | 5 |
| ACTR3C | EPB41L3 | 0.708328 | 5 | 0 | 4 |
| ACTR3C | INPP5D | 0.70555 | 3 | 0 | 3 |
| ACTR3C | CDA | 0.702545 | 4 | 0 | 4 |
| ACTR3C | ELMO2 | 0.699418 | 5 | 0 | 5 |
| ACTR3C | ANO10 | 0.699251 | 4 | 0 | 4 |
| ACTR3C | OXNAD1 | 0.698493 | 4 | 0 | 4 |
For details and further investigation, click here
