| Full name: thioredoxin domain containing 17 | Alias Symbol: MGC14353|TRP14 | ||
| Type: protein-coding gene | Cytoband: 17p13.1 | ||
| Entrez ID: 84817 | HGNC ID: HGNC:28218 | Ensembl Gene: ENSG00000129235 | OMIM ID: 616967 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of TXNDC17:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TXNDC17 | 84817 | 224511_s_at | -0.1502 | 0.8584 | |
| GSE26886 | TXNDC17 | 84817 | 224511_s_at | -0.4139 | 0.0401 | |
| GSE45670 | TXNDC17 | 84817 | 224511_s_at | 0.0957 | 0.6421 | |
| GSE63941 | TXNDC17 | 84817 | 224511_s_at | 0.5207 | 0.1623 | |
| GSE77861 | TXNDC17 | 84817 | 224511_s_at | -0.4676 | 0.0180 | |
| GSE97050 | TXNDC17 | 84817 | A_33_P3209386 | 0.0977 | 0.7208 | |
| SRP007169 | TXNDC17 | 84817 | RNAseq | -1.9172 | 0.0000 | |
| SRP008496 | TXNDC17 | 84817 | RNAseq | -1.9064 | 0.0000 | |
| SRP064894 | TXNDC17 | 84817 | RNAseq | -0.8363 | 0.0029 | |
| SRP133303 | TXNDC17 | 84817 | RNAseq | -0.7960 | 0.0001 | |
| SRP159526 | TXNDC17 | 84817 | RNAseq | -1.1133 | 0.0018 | |
| SRP193095 | TXNDC17 | 84817 | RNAseq | -1.0866 | 0.0000 | |
| SRP219564 | TXNDC17 | 84817 | RNAseq | -0.8764 | 0.2305 | |
| TCGA | TXNDC17 | 84817 | RNAseq | 0.1283 | 0.1263 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by TXNDC17 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of TXNDC17:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TXNDC17 | 84817 | 4 | 2 | 24 | |
| GSE20123 | TXNDC17 | 84817 | 4 | 3 | 23 | |
| GSE43470 | TXNDC17 | 84817 | 1 | 6 | 36 | |
| GSE46452 | TXNDC17 | 84817 | 34 | 1 | 24 | |
| GSE47630 | TXNDC17 | 84817 | 7 | 1 | 32 | |
| GSE54993 | TXNDC17 | 84817 | 4 | 3 | 63 | |
| GSE54994 | TXNDC17 | 84817 | 5 | 8 | 40 | |
| GSE60625 | TXNDC17 | 84817 | 4 | 0 | 7 | |
| GSE74703 | TXNDC17 | 84817 | 1 | 3 | 32 | |
| GSE74704 | TXNDC17 | 84817 | 2 | 1 | 17 | |
| TCGA | TXNDC17 | 84817 | 18 | 20 | 58 |
Total number of gains: 84; Total number of losses: 48; Total Number of normals: 356.
Somatic mutations of TXNDC17:
Generating mutation plots.
Highly correlated genes for TXNDC17:
Showing top 20/383 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TXNDC17 | SSU72 | 0.781977 | 3 | 0 | 3 |
| TXNDC17 | RER1 | 0.776088 | 3 | 0 | 3 |
| TXNDC17 | ACTR3C | 0.762109 | 3 | 0 | 3 |
| TXNDC17 | PGGT1B | 0.752882 | 3 | 0 | 3 |
| TXNDC17 | RAB25 | 0.727571 | 3 | 0 | 3 |
| TXNDC17 | HSD17B4 | 0.725117 | 3 | 0 | 3 |
| TXNDC17 | TAF13 | 0.721874 | 3 | 0 | 3 |
| TXNDC17 | PPIP5K2 | 0.718084 | 3 | 0 | 3 |
| TXNDC17 | TMEM161B | 0.716233 | 4 | 0 | 4 |
| TXNDC17 | SLC25A43 | 0.71207 | 3 | 0 | 3 |
| TXNDC17 | GSKIP | 0.708474 | 4 | 0 | 4 |
| TXNDC17 | RINT1 | 0.706749 | 3 | 0 | 3 |
| TXNDC17 | UBXN8 | 0.704684 | 3 | 0 | 3 |
| TXNDC17 | AKR1A1 | 0.703356 | 4 | 0 | 4 |
| TXNDC17 | PTBP3 | 0.69486 | 4 | 0 | 3 |
| TXNDC17 | PRKCH | 0.687918 | 3 | 0 | 3 |
| TXNDC17 | CNKSR1 | 0.687522 | 4 | 0 | 3 |
| TXNDC17 | CRLF3 | 0.682898 | 3 | 0 | 3 |
| TXNDC17 | CABLES1 | 0.682742 | 3 | 0 | 3 |
| TXNDC17 | HERC4 | 0.679616 | 3 | 0 | 3 |
For details and further investigation, click here
