| Full name: CD2 associated protein | Alias Symbol: CMS | ||
| Type: protein-coding gene | Cytoband: 6p12.3 | ||
| Entrez ID: 23607 | HGNC ID: HGNC:14258 | Ensembl Gene: ENSG00000198087 | OMIM ID: 604241 |
| Drug and gene relationship at DGIdb | |||
Expression of CD2AP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CD2AP | 23607 | 203593_at | -0.2540 | 0.6179 | |
| GSE20347 | CD2AP | 23607 | 203593_at | -0.7266 | 0.0001 | |
| GSE23400 | CD2AP | 23607 | 203593_at | -0.2171 | 0.0374 | |
| GSE26886 | CD2AP | 23607 | 203593_at | -1.0516 | 0.0000 | |
| GSE29001 | CD2AP | 23607 | 203593_at | -0.5943 | 0.0462 | |
| GSE38129 | CD2AP | 23607 | 203593_at | -0.3660 | 0.0431 | |
| GSE45670 | CD2AP | 23607 | 203593_at | -0.1704 | 0.4173 | |
| GSE53622 | CD2AP | 23607 | 105476 | -0.7895 | 0.0000 | |
| GSE53624 | CD2AP | 23607 | 105476 | -0.4372 | 0.0000 | |
| GSE63941 | CD2AP | 23607 | 203593_at | -0.2056 | 0.6616 | |
| GSE77861 | CD2AP | 23607 | 203593_at | -0.7915 | 0.0405 | |
| GSE97050 | CD2AP | 23607 | A_32_P155811 | -0.3154 | 0.3246 | |
| SRP007169 | CD2AP | 23607 | RNAseq | -0.3756 | 0.3342 | |
| SRP008496 | CD2AP | 23607 | RNAseq | -0.5045 | 0.0309 | |
| SRP064894 | CD2AP | 23607 | RNAseq | -0.6485 | 0.0055 | |
| SRP133303 | CD2AP | 23607 | RNAseq | -0.0739 | 0.6192 | |
| SRP159526 | CD2AP | 23607 | RNAseq | -0.6018 | 0.0640 | |
| SRP193095 | CD2AP | 23607 | RNAseq | -0.9536 | 0.0000 | |
| SRP219564 | CD2AP | 23607 | RNAseq | -0.7742 | 0.1220 | |
| TCGA | CD2AP | 23607 | RNAseq | -0.0707 | 0.1964 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CD2AP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CD2AP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CD2AP | 23607 | 5 | 2 | 23 | |
| GSE20123 | CD2AP | 23607 | 5 | 2 | 23 | |
| GSE43470 | CD2AP | 23607 | 5 | 0 | 38 | |
| GSE46452 | CD2AP | 23607 | 2 | 10 | 47 | |
| GSE47630 | CD2AP | 23607 | 7 | 5 | 28 | |
| GSE54993 | CD2AP | 23607 | 3 | 1 | 66 | |
| GSE54994 | CD2AP | 23607 | 8 | 3 | 42 | |
| GSE60625 | CD2AP | 23607 | 0 | 3 | 8 | |
| GSE74703 | CD2AP | 23607 | 5 | 0 | 31 | |
| GSE74704 | CD2AP | 23607 | 1 | 1 | 18 | |
| TCGA | CD2AP | 23607 | 20 | 14 | 62 |
Total number of gains: 61; Total number of losses: 41; Total Number of normals: 386.
Somatic mutations of CD2AP:
Generating mutation plots.
Highly correlated genes for CD2AP:
Showing top 20/1430 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CD2AP | RBM20 | 0.827577 | 3 | 0 | 3 |
| CD2AP | HDHD2 | 0.826252 | 3 | 0 | 3 |
| CD2AP | UBLCP1 | 0.817415 | 3 | 0 | 3 |
| CD2AP | CCNYL1 | 0.806244 | 4 | 0 | 4 |
| CD2AP | SH3PXD2A-AS1 | 0.788388 | 3 | 0 | 3 |
| CD2AP | GSKIP | 0.781564 | 4 | 0 | 4 |
| CD2AP | LINC00551 | 0.777856 | 3 | 0 | 3 |
| CD2AP | ECHDC1 | 0.771262 | 3 | 0 | 3 |
| CD2AP | CARD16 | 0.764545 | 3 | 0 | 3 |
| CD2AP | BRK1 | 0.754149 | 4 | 0 | 4 |
| CD2AP | PSMD6-AS2 | 0.748725 | 3 | 0 | 3 |
| CD2AP | ZNF92 | 0.742559 | 3 | 0 | 3 |
| CD2AP | FRMD4B | 0.740858 | 9 | 0 | 9 |
| CD2AP | SPAG17 | 0.738131 | 3 | 0 | 3 |
| CD2AP | KCTD21 | 0.735093 | 4 | 0 | 4 |
| CD2AP | RAD17 | 0.732151 | 4 | 0 | 4 |
| CD2AP | WBP2 | 0.730818 | 3 | 0 | 3 |
| CD2AP | KCNK6 | 0.7252 | 4 | 0 | 4 |
| CD2AP | SFTA2 | 0.723963 | 3 | 0 | 3 |
| CD2AP | SMIM15 | 0.719879 | 4 | 0 | 3 |
For details and further investigation, click here
