| Full name: oxysterol binding protein like 10 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3p23 | ||
| Entrez ID: 114884 | HGNC ID: HGNC:16395 | Ensembl Gene: ENSG00000144645 | OMIM ID: 606738 |
| Drug and gene relationship at DGIdb | |||
Expression of OSBPL10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OSBPL10 | 114884 | 219073_s_at | -0.9600 | 0.2887 | |
| GSE20347 | OSBPL10 | 114884 | 219073_s_at | -1.5509 | 0.0000 | |
| GSE23400 | OSBPL10 | 114884 | 216755_at | -0.1343 | 0.0084 | |
| GSE26886 | OSBPL10 | 114884 | 219073_s_at | -1.5908 | 0.0001 | |
| GSE29001 | OSBPL10 | 114884 | 219073_s_at | -1.2719 | 0.0010 | |
| GSE38129 | OSBPL10 | 114884 | 219073_s_at | -1.3700 | 0.0000 | |
| GSE45670 | OSBPL10 | 114884 | 219073_s_at | -0.6963 | 0.0076 | |
| GSE53622 | OSBPL10 | 114884 | 7371 | -1.1428 | 0.0000 | |
| GSE53624 | OSBPL10 | 114884 | 7371 | -1.1577 | 0.0000 | |
| GSE63941 | OSBPL10 | 114884 | 219073_s_at | -1.1816 | 0.0597 | |
| GSE77861 | OSBPL10 | 114884 | 219073_s_at | -1.3584 | 0.0016 | |
| GSE97050 | OSBPL10 | 114884 | A_23_P147245 | 0.1641 | 0.8067 | |
| SRP007169 | OSBPL10 | 114884 | RNAseq | -2.2946 | 0.0000 | |
| SRP008496 | OSBPL10 | 114884 | RNAseq | -2.2001 | 0.0000 | |
| SRP064894 | OSBPL10 | 114884 | RNAseq | -1.2128 | 0.0000 | |
| SRP133303 | OSBPL10 | 114884 | RNAseq | -1.0038 | 0.0000 | |
| SRP159526 | OSBPL10 | 114884 | RNAseq | -1.5816 | 0.0000 | |
| SRP193095 | OSBPL10 | 114884 | RNAseq | -0.8880 | 0.0000 | |
| SRP219564 | OSBPL10 | 114884 | RNAseq | -1.0494 | 0.0071 | |
| TCGA | OSBPL10 | 114884 | RNAseq | -0.1291 | 0.1266 |
Upregulated datasets: 0; Downregulated datasets: 13.
Survival by OSBPL10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OSBPL10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OSBPL10 | 114884 | 0 | 18 | 12 | |
| GSE20123 | OSBPL10 | 114884 | 0 | 18 | 12 | |
| GSE43470 | OSBPL10 | 114884 | 1 | 20 | 22 | |
| GSE46452 | OSBPL10 | 114884 | 2 | 17 | 40 | |
| GSE47630 | OSBPL10 | 114884 | 1 | 25 | 14 | |
| GSE54993 | OSBPL10 | 114884 | 6 | 3 | 61 | |
| GSE54994 | OSBPL10 | 114884 | 1 | 32 | 20 | |
| GSE60625 | OSBPL10 | 114884 | 5 | 0 | 6 | |
| GSE74703 | OSBPL10 | 114884 | 1 | 17 | 18 | |
| GSE74704 | OSBPL10 | 114884 | 0 | 12 | 8 | |
| TCGA | OSBPL10 | 114884 | 1 | 69 | 26 |
Total number of gains: 18; Total number of losses: 231; Total Number of normals: 239.
Somatic mutations of OSBPL10:
Generating mutation plots.
Highly correlated genes for OSBPL10:
Showing top 20/1467 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OSBPL10 | PDCD6IP | 0.806428 | 10 | 0 | 10 |
| OSBPL10 | FCHO2 | 0.792983 | 7 | 0 | 7 |
| OSBPL10 | A2ML1 | 0.79247 | 6 | 0 | 6 |
| OSBPL10 | CYSRT1 | 0.787915 | 6 | 0 | 6 |
| OSBPL10 | CWH43 | 0.782581 | 9 | 0 | 9 |
| OSBPL10 | VSIG10L | 0.781265 | 6 | 0 | 6 |
| OSBPL10 | SLC16A6 | 0.764532 | 10 | 0 | 10 |
| OSBPL10 | CAPN14 | 0.763985 | 6 | 0 | 6 |
| OSBPL10 | CAST | 0.762294 | 10 | 0 | 10 |
| OSBPL10 | CCDC6 | 0.759659 | 9 | 0 | 9 |
| OSBPL10 | CNFN | 0.758279 | 6 | 0 | 6 |
| OSBPL10 | RBM20 | 0.756798 | 4 | 0 | 4 |
| OSBPL10 | CA13 | 0.75627 | 3 | 0 | 3 |
| OSBPL10 | SLC46A2 | 0.754633 | 7 | 0 | 7 |
| OSBPL10 | UBL3 | 0.754253 | 9 | 0 | 9 |
| OSBPL10 | DHRS1 | 0.752777 | 9 | 0 | 9 |
| OSBPL10 | VSIG2 | 0.752531 | 5 | 0 | 5 |
| OSBPL10 | GMDS | 0.751822 | 9 | 0 | 9 |
| OSBPL10 | PDLIM2 | 0.750954 | 8 | 0 | 8 |
| OSBPL10 | TMPRSS11B | 0.750818 | 6 | 0 | 6 |
For details and further investigation, click here
