| Full name: anoctamin 10 | Alias Symbol: FLJ10375|MGC47890|SCAR10 | ||
| Type: protein-coding gene | Cytoband: 3p22.1-p21.33 | ||
| Entrez ID: 55129 | HGNC ID: HGNC:25519 | Ensembl Gene: ENSG00000160746 | OMIM ID: 613726 |
| Drug and gene relationship at DGIdb | |||
Expression of ANO10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ANO10 | 55129 | 218910_at | -0.4318 | 0.2753 | |
| GSE20347 | ANO10 | 55129 | 218910_at | -1.2438 | 0.0000 | |
| GSE23400 | ANO10 | 55129 | 218910_at | -0.6925 | 0.0000 | |
| GSE26886 | ANO10 | 55129 | 218910_at | -0.2045 | 0.2464 | |
| GSE29001 | ANO10 | 55129 | 218910_at | -1.2476 | 0.0000 | |
| GSE38129 | ANO10 | 55129 | 218910_at | -1.0551 | 0.0000 | |
| GSE45670 | ANO10 | 55129 | 218910_at | -0.5365 | 0.0020 | |
| GSE53622 | ANO10 | 55129 | 150108 | -1.0085 | 0.0000 | |
| GSE53624 | ANO10 | 55129 | 150108 | -0.9716 | 0.0000 | |
| GSE63941 | ANO10 | 55129 | 218910_at | -1.5476 | 0.0022 | |
| GSE77861 | ANO10 | 55129 | 218910_at | -1.1284 | 0.0010 | |
| GSE97050 | ANO10 | 55129 | A_33_P3328426 | -0.5223 | 0.1406 | |
| SRP007169 | ANO10 | 55129 | RNAseq | -2.1280 | 0.0000 | |
| SRP008496 | ANO10 | 55129 | RNAseq | -1.9581 | 0.0000 | |
| SRP064894 | ANO10 | 55129 | RNAseq | -0.6870 | 0.0001 | |
| SRP133303 | ANO10 | 55129 | RNAseq | -0.8449 | 0.0000 | |
| SRP159526 | ANO10 | 55129 | RNAseq | -1.0914 | 0.0001 | |
| SRP193095 | ANO10 | 55129 | RNAseq | -1.1082 | 0.0000 | |
| SRP219564 | ANO10 | 55129 | RNAseq | -0.9058 | 0.0083 | |
| TCGA | ANO10 | 55129 | RNAseq | -0.2064 | 0.0021 |
Upregulated datasets: 0; Downregulated datasets: 10.
Survival by ANO10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ANO10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ANO10 | 55129 | 0 | 19 | 11 | |
| GSE20123 | ANO10 | 55129 | 0 | 19 | 11 | |
| GSE43470 | ANO10 | 55129 | 0 | 21 | 22 | |
| GSE46452 | ANO10 | 55129 | 2 | 17 | 40 | |
| GSE47630 | ANO10 | 55129 | 1 | 24 | 15 | |
| GSE54993 | ANO10 | 55129 | 7 | 2 | 61 | |
| GSE54994 | ANO10 | 55129 | 1 | 34 | 18 | |
| GSE60625 | ANO10 | 55129 | 5 | 0 | 6 | |
| GSE74703 | ANO10 | 55129 | 0 | 16 | 20 | |
| GSE74704 | ANO10 | 55129 | 0 | 13 | 7 | |
| TCGA | ANO10 | 55129 | 1 | 72 | 23 |
Total number of gains: 17; Total number of losses: 237; Total Number of normals: 234.
Somatic mutations of ANO10:
Generating mutation plots.
Highly correlated genes for ANO10:
Showing top 20/1595 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ANO10 | RAB5A | 0.872111 | 10 | 0 | 10 |
| ANO10 | LRRFIP2 | 0.814189 | 11 | 0 | 11 |
| ANO10 | RMND5B | 0.814107 | 10 | 0 | 10 |
| ANO10 | MAP1A | 0.800167 | 3 | 0 | 3 |
| ANO10 | PINK1 | 0.799455 | 9 | 0 | 9 |
| ANO10 | FCHO2 | 0.796437 | 6 | 0 | 6 |
| ANO10 | MRPS25 | 0.796095 | 3 | 0 | 3 |
| ANO10 | TP53I3 | 0.795659 | 10 | 0 | 10 |
| ANO10 | ARHGEF10L | 0.787632 | 10 | 0 | 10 |
| ANO10 | SORT1 | 0.786094 | 10 | 0 | 9 |
| ANO10 | FIBIN | 0.785972 | 3 | 0 | 3 |
| ANO10 | CRYL1 | 0.77878 | 10 | 0 | 10 |
| ANO10 | SLC46A2 | 0.778043 | 6 | 0 | 6 |
| ANO10 | ATP6V1G1 | 0.77782 | 3 | 0 | 3 |
| ANO10 | CGNL1 | 0.776436 | 5 | 0 | 5 |
| ANO10 | MOV10L1 | 0.775961 | 3 | 0 | 3 |
| ANO10 | ACAA1 | 0.773971 | 10 | 0 | 9 |
| ANO10 | DHRS1 | 0.772562 | 10 | 0 | 9 |
| ANO10 | MRPS36 | 0.772493 | 6 | 0 | 6 |
| ANO10 | UPK1A | 0.772074 | 9 | 0 | 9 |
For details and further investigation, click here
