| Full name: chromosome 2 open reading frame 16 | Alias Symbol: DKFZp434G118 | ||
| Type: protein-coding gene | Cytoband: 2p23.3 | ||
| Entrez ID: 84226 | HGNC ID: HGNC:25275 | Ensembl Gene: ENSG00000221843 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C2orf16:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C2orf16 | 84226 | 224000_at | -0.3848 | 0.1641 | |
| GSE26886 | C2orf16 | 84226 | 224000_at | -0.5726 | 0.0003 | |
| GSE45670 | C2orf16 | 84226 | 224000_at | -0.1642 | 0.2341 | |
| GSE53622 | C2orf16 | 84226 | 24978 | -0.3495 | 0.0115 | |
| GSE53624 | C2orf16 | 84226 | 24978 | -1.2286 | 0.0000 | |
| GSE63941 | C2orf16 | 84226 | 224000_at | 0.3086 | 0.0995 | |
| GSE77861 | C2orf16 | 84226 | 224000_at | -0.2940 | 0.0153 | |
| GSE97050 | C2orf16 | 84226 | A_24_P222890 | 0.0040 | 0.9884 | |
| SRP064894 | C2orf16 | 84226 | RNAseq | -0.7219 | 0.0138 | |
| SRP133303 | C2orf16 | 84226 | RNAseq | -0.2876 | 0.2702 | |
| SRP159526 | C2orf16 | 84226 | RNAseq | 0.5409 | 0.3109 | |
| SRP193095 | C2orf16 | 84226 | RNAseq | -0.4107 | 0.0380 | |
| TCGA | C2orf16 | 84226 | RNAseq | -0.1047 | 0.5014 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by C2orf16 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C2orf16:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C2orf16 | 84226 | 11 | 2 | 17 | |
| GSE20123 | C2orf16 | 84226 | 11 | 2 | 17 | |
| GSE43470 | C2orf16 | 84226 | 3 | 1 | 39 | |
| GSE46452 | C2orf16 | 84226 | 2 | 4 | 53 | |
| GSE47630 | C2orf16 | 84226 | 8 | 0 | 32 | |
| GSE54993 | C2orf16 | 84226 | 0 | 6 | 64 | |
| GSE54994 | C2orf16 | 84226 | 10 | 0 | 43 | |
| GSE60625 | C2orf16 | 84226 | 0 | 3 | 8 | |
| GSE74703 | C2orf16 | 84226 | 3 | 0 | 33 | |
| GSE74704 | C2orf16 | 84226 | 9 | 1 | 10 | |
| TCGA | C2orf16 | 84226 | 36 | 2 | 58 |
Total number of gains: 93; Total number of losses: 21; Total Number of normals: 374.
Somatic mutations of C2orf16:
Generating mutation plots.
Highly correlated genes for C2orf16:
Showing top 20/778 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C2orf16 | ALG9 | 0.862308 | 3 | 0 | 3 |
| C2orf16 | GNG5 | 0.813956 | 3 | 0 | 3 |
| C2orf16 | APEH | 0.791819 | 3 | 0 | 3 |
| C2orf16 | XKR6 | 0.763275 | 3 | 0 | 3 |
| C2orf16 | ADRB3 | 0.748574 | 3 | 0 | 3 |
| C2orf16 | MYCN | 0.735963 | 3 | 0 | 3 |
| C2orf16 | CLTA | 0.733313 | 3 | 0 | 3 |
| C2orf16 | ACTR3C | 0.730493 | 3 | 0 | 3 |
| C2orf16 | KCNJ5 | 0.727356 | 5 | 0 | 4 |
| C2orf16 | CACNG6 | 0.726873 | 5 | 0 | 5 |
| C2orf16 | SREBF2 | 0.726386 | 3 | 0 | 3 |
| C2orf16 | LRP11 | 0.721424 | 3 | 0 | 3 |
| C2orf16 | SLAMF7 | 0.715746 | 3 | 0 | 3 |
| C2orf16 | DENND4C | 0.712777 | 3 | 0 | 3 |
| C2orf16 | FBXO10 | 0.712224 | 4 | 0 | 3 |
| C2orf16 | SMR3B | 0.711936 | 4 | 0 | 4 |
| C2orf16 | CCDC154 | 0.711027 | 5 | 0 | 5 |
| C2orf16 | ELL3 | 0.710678 | 4 | 0 | 4 |
| C2orf16 | LINC01210 | 0.7106 | 4 | 0 | 3 |
| C2orf16 | VPS37B | 0.709947 | 5 | 0 | 5 |
For details and further investigation, click here
