| Full name: transmembrane protein 174 | Alias Symbol: MGC13034|FLJ31268 | ||
| Type: protein-coding gene | Cytoband: 5q13.2 | ||
| Entrez ID: 134288 | HGNC ID: HGNC:28187 | Ensembl Gene: ENSG00000164325 | OMIM ID: 614909 |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM174:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM174 | 134288 | 240114_s_at | 0.0856 | 0.7449 | |
| GSE26886 | TMEM174 | 134288 | 240114_s_at | -0.0463 | 0.8039 | |
| GSE45670 | TMEM174 | 134288 | 240114_s_at | 0.1478 | 0.0852 | |
| GSE53622 | TMEM174 | 134288 | 103619 | -0.1729 | 0.0056 | |
| GSE53624 | TMEM174 | 134288 | 103619 | -0.2105 | 0.0125 | |
| GSE63941 | TMEM174 | 134288 | 240114_s_at | -0.1251 | 0.4633 | |
| GSE77861 | TMEM174 | 134288 | 240114_s_at | 0.0779 | 0.6573 | |
| GSE97050 | TMEM174 | 134288 | A_23_P344594 | -0.2053 | 0.3528 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TMEM174 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM174:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM174 | 134288 | 1 | 13 | 16 | |
| GSE20123 | TMEM174 | 134288 | 1 | 13 | 16 | |
| GSE43470 | TMEM174 | 134288 | 1 | 13 | 29 | |
| GSE46452 | TMEM174 | 134288 | 0 | 28 | 31 | |
| GSE47630 | TMEM174 | 134288 | 1 | 19 | 20 | |
| GSE54993 | TMEM174 | 134288 | 8 | 1 | 61 | |
| GSE54994 | TMEM174 | 134288 | 1 | 19 | 33 | |
| GSE60625 | TMEM174 | 134288 | 0 | 0 | 11 | |
| GSE74703 | TMEM174 | 134288 | 1 | 9 | 26 | |
| GSE74704 | TMEM174 | 134288 | 1 | 6 | 13 | |
| TCGA | TMEM174 | 134288 | 4 | 51 | 41 |
Total number of gains: 19; Total number of losses: 172; Total Number of normals: 297.
Somatic mutations of TMEM174:
Generating mutation plots.
Highly correlated genes for TMEM174:
Showing top 20/129 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM174 | SIM1 | 0.713324 | 4 | 0 | 4 |
| TMEM174 | C8orf58 | 0.705594 | 3 | 0 | 3 |
| TMEM174 | CIB2 | 0.67518 | 3 | 0 | 3 |
| TMEM174 | GPSM1 | 0.673806 | 3 | 0 | 3 |
| TMEM174 | ADAM33 | 0.670037 | 4 | 0 | 3 |
| TMEM174 | LINC00486 | 0.663215 | 4 | 0 | 3 |
| TMEM174 | ASB16 | 0.658808 | 5 | 0 | 4 |
| TMEM174 | NOBOX | 0.65476 | 5 | 0 | 5 |
| TMEM174 | MME | 0.65254 | 4 | 0 | 4 |
| TMEM174 | KCTD19 | 0.650394 | 3 | 0 | 3 |
| TMEM174 | DSCR10 | 0.647889 | 4 | 0 | 4 |
| TMEM174 | LCNL1 | 0.642618 | 4 | 0 | 4 |
| TMEM174 | DUSP8 | 0.641473 | 3 | 0 | 3 |
| TMEM174 | TXNDC2 | 0.635432 | 4 | 0 | 3 |
| TMEM174 | NUTM1 | 0.630416 | 4 | 0 | 4 |
| TMEM174 | KIRREL2 | 0.629789 | 4 | 0 | 3 |
| TMEM174 | ULK2 | 0.629102 | 5 | 0 | 5 |
| TMEM174 | SCRG1 | 0.627249 | 4 | 0 | 3 |
| TMEM174 | ANKRD53 | 0.623447 | 4 | 0 | 3 |
| TMEM174 | HMX1 | 0.623101 | 3 | 0 | 3 |
For details and further investigation, click here
