| Full name: ADAM metallopeptidase with thrombospondin type 1 motif 19 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 5q23.3 | ||
| Entrez ID: 171019 | HGNC ID: HGNC:17111 | Ensembl Gene: ENSG00000145808 | OMIM ID: 607513 |
| Drug and gene relationship at DGIdb | |||
Expression of ADAMTS19:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ADAMTS19 | 171019 | 1553179_at | -0.4740 | 0.6191 | |
| GSE26886 | ADAMTS19 | 171019 | 1553179_at | 0.0677 | 0.5446 | |
| GSE45670 | ADAMTS19 | 171019 | 1553179_at | -0.0446 | 0.7114 | |
| GSE53622 | ADAMTS19 | 171019 | 23327 | -0.1746 | 0.2477 | |
| GSE53624 | ADAMTS19 | 171019 | 23327 | -0.4097 | 0.0004 | |
| GSE63941 | ADAMTS19 | 171019 | 1553179_at | -1.6891 | 0.0000 | |
| GSE77861 | ADAMTS19 | 171019 | 1553179_at | -0.1470 | 0.1267 | |
| GSE97050 | ADAMTS19 | 171019 | A_33_P3317392 | -0.4625 | 0.2743 | |
| SRP133303 | ADAMTS19 | 171019 | RNAseq | -0.4092 | 0.6984 | |
| TCGA | ADAMTS19 | 171019 | RNAseq | -0.8572 | 0.4164 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ADAMTS19 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ADAMTS19:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ADAMTS19 | 171019 | 1 | 12 | 17 | |
| GSE20123 | ADAMTS19 | 171019 | 1 | 12 | 17 | |
| GSE43470 | ADAMTS19 | 171019 | 3 | 8 | 32 | |
| GSE46452 | ADAMTS19 | 171019 | 0 | 27 | 32 | |
| GSE47630 | ADAMTS19 | 171019 | 0 | 21 | 19 | |
| GSE54993 | ADAMTS19 | 171019 | 9 | 1 | 60 | |
| GSE54994 | ADAMTS19 | 171019 | 2 | 14 | 37 | |
| GSE60625 | ADAMTS19 | 171019 | 0 | 0 | 11 | |
| GSE74703 | ADAMTS19 | 171019 | 2 | 6 | 28 | |
| GSE74704 | ADAMTS19 | 171019 | 1 | 6 | 13 | |
| TCGA | ADAMTS19 | 171019 | 2 | 41 | 53 |
Total number of gains: 21; Total number of losses: 148; Total Number of normals: 319.
Somatic mutations of ADAMTS19:
Generating mutation plots.
Highly correlated genes for ADAMTS19:
Showing top 20/175 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ADAMTS19 | NPR2 | 0.800375 | 3 | 0 | 3 |
| ADAMTS19 | ZNF781 | 0.793758 | 3 | 0 | 3 |
| ADAMTS19 | NME5 | 0.726295 | 3 | 0 | 3 |
| ADAMTS19 | DENND2A | 0.723351 | 4 | 0 | 3 |
| ADAMTS19 | ABLIM3 | 0.718762 | 3 | 0 | 3 |
| ADAMTS19 | AFF3 | 0.715977 | 3 | 0 | 3 |
| ADAMTS19 | WNT5B | 0.714791 | 3 | 0 | 3 |
| ADAMTS19 | IL17B | 0.71422 | 3 | 0 | 3 |
| ADAMTS19 | GRIK3 | 0.702855 | 3 | 0 | 3 |
| ADAMTS19 | NPTX1 | 0.701253 | 3 | 0 | 3 |
| ADAMTS19 | NLGN1 | 0.699172 | 3 | 0 | 3 |
| ADAMTS19 | ZNF582 | 0.694346 | 3 | 0 | 3 |
| ADAMTS19 | TCEAL7 | 0.693392 | 4 | 0 | 4 |
| ADAMTS19 | SMIM10 | 0.687641 | 3 | 0 | 3 |
| ADAMTS19 | CACNA1C | 0.684113 | 3 | 0 | 3 |
| ADAMTS19 | CTIF | 0.683734 | 4 | 0 | 4 |
| ADAMTS19 | GNG8 | 0.68089 | 3 | 0 | 3 |
| ADAMTS19 | JAZF1-AS1 | 0.680146 | 4 | 0 | 3 |
| ADAMTS19 | GDNF | 0.678194 | 5 | 0 | 3 |
| ADAMTS19 | LAMA4 | 0.672336 | 3 | 0 | 3 |
For details and further investigation, click here
