| Full name: NME/NM23 family member 5 | Alias Symbol: nm23-H5|RSPH23 | ||
| Type: protein-coding gene | Cytoband: 5q31.2 | ||
| Entrez ID: 8382 | HGNC ID: HGNC:7853 | Ensembl Gene: ENSG00000112981 | OMIM ID: 603575 |
| Drug and gene relationship at DGIdb | |||
Expression of NME5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NME5 | 8382 | 206197_at | -0.8152 | 0.1332 | |
| GSE20347 | NME5 | 8382 | 206197_at | -0.1502 | 0.1187 | |
| GSE23400 | NME5 | 8382 | 206197_at | -0.1496 | 0.0001 | |
| GSE26886 | NME5 | 8382 | 206197_at | 0.1344 | 0.3515 | |
| GSE29001 | NME5 | 8382 | 206197_at | -0.4769 | 0.0175 | |
| GSE38129 | NME5 | 8382 | 206197_at | -0.5678 | 0.0421 | |
| GSE45670 | NME5 | 8382 | 206197_at | -0.8355 | 0.0000 | |
| GSE53622 | NME5 | 8382 | 42197 | -1.9158 | 0.0000 | |
| GSE53624 | NME5 | 8382 | 42197 | -1.7510 | 0.0000 | |
| GSE63941 | NME5 | 8382 | 206197_at | -3.2796 | 0.0000 | |
| GSE77861 | NME5 | 8382 | 206197_at | -0.1419 | 0.1528 | |
| GSE97050 | NME5 | 8382 | A_23_P156402 | -0.5901 | 0.2004 | |
| SRP064894 | NME5 | 8382 | RNAseq | -1.1614 | 0.0042 | |
| TCGA | NME5 | 8382 | RNAseq | -3.1960 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by NME5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NME5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NME5 | 8382 | 3 | 10 | 17 | |
| GSE20123 | NME5 | 8382 | 4 | 10 | 16 | |
| GSE43470 | NME5 | 8382 | 4 | 5 | 34 | |
| GSE46452 | NME5 | 8382 | 0 | 27 | 32 | |
| GSE47630 | NME5 | 8382 | 0 | 21 | 19 | |
| GSE54993 | NME5 | 8382 | 9 | 1 | 60 | |
| GSE54994 | NME5 | 8382 | 3 | 13 | 37 | |
| GSE60625 | NME5 | 8382 | 0 | 0 | 11 | |
| GSE74703 | NME5 | 8382 | 3 | 4 | 29 | |
| GSE74704 | NME5 | 8382 | 3 | 4 | 13 | |
| TCGA | NME5 | 8382 | 4 | 36 | 56 |
Total number of gains: 33; Total number of losses: 131; Total Number of normals: 324.
Somatic mutations of NME5:
Generating mutation plots.
Highly correlated genes for NME5:
Showing top 20/1332 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NME5 | PNMA2 | 0.887419 | 3 | 0 | 3 |
| NME5 | UBXN10 | 0.873927 | 3 | 0 | 3 |
| NME5 | SORCS1 | 0.86052 | 4 | 0 | 4 |
| NME5 | MSRB3 | 0.817448 | 6 | 0 | 6 |
| NME5 | FIBIN | 0.817134 | 4 | 0 | 4 |
| NME5 | MAGI2-AS3 | 0.816205 | 5 | 0 | 5 |
| NME5 | ANO5 | 0.814622 | 6 | 0 | 6 |
| NME5 | MRVI1 | 0.809645 | 6 | 0 | 6 |
| NME5 | C1QTNF7 | 0.801239 | 6 | 0 | 6 |
| NME5 | BHMT2 | 0.799974 | 9 | 0 | 9 |
| NME5 | FENDRR | 0.797203 | 5 | 0 | 5 |
| NME5 | RASD2 | 0.792618 | 3 | 0 | 3 |
| NME5 | RSPO2 | 0.792434 | 3 | 0 | 3 |
| NME5 | LINC01082 | 0.790496 | 5 | 0 | 5 |
| NME5 | SMIM10 | 0.790342 | 5 | 0 | 5 |
| NME5 | ANGPTL1 | 0.787255 | 6 | 0 | 6 |
| NME5 | MYOCD | 0.779146 | 6 | 0 | 5 |
| NME5 | TRAK1 | 0.778093 | 4 | 0 | 4 |
| NME5 | NFASC | 0.774554 | 6 | 0 | 6 |
| NME5 | RBPMS2 | 0.774238 | 6 | 0 | 5 |
For details and further investigation, click here
