| Full name: G protein subunit gamma 8 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19q13.32 | ||
| Entrez ID: 94235 | HGNC ID: HGNC:19664 | Ensembl Gene: | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
GNG8 involved pathways:
Expression of GNG8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GNG8 | 94235 | 234284_at | -0.1151 | 0.5954 | |
| GSE26886 | GNG8 | 94235 | 234284_at | 0.3522 | 0.0621 | |
| GSE45670 | GNG8 | 94235 | 234284_at | -0.1433 | 0.1339 | |
| GSE53622 | GNG8 | 94235 | 11458 | 0.3003 | 0.0243 | |
| GSE53624 | GNG8 | 94235 | 11458 | 0.1291 | 0.1075 | |
| GSE63941 | GNG8 | 94235 | 234284_at | -0.1198 | 0.4667 | |
| GSE77861 | GNG8 | 94235 | 234284_at | -0.2452 | 0.1150 | |
| GSE97050 | GNG8 | 94235 | A_24_P79070 | -0.0970 | 0.7103 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GNG8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GNG8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GNG8 | 94235 | 4 | 4 | 22 | |
| GSE20123 | GNG8 | 94235 | 4 | 3 | 23 | |
| GSE43470 | GNG8 | 94235 | 3 | 11 | 29 | |
| GSE46452 | GNG8 | 94235 | 45 | 1 | 13 | |
| GSE47630 | GNG8 | 94235 | 8 | 7 | 25 | |
| GSE54993 | GNG8 | 94235 | 17 | 4 | 49 | |
| GSE54994 | GNG8 | 94235 | 5 | 13 | 35 | |
| GSE60625 | GNG8 | 94235 | 9 | 0 | 2 | |
| GSE74703 | GNG8 | 94235 | 3 | 7 | 26 | |
| GSE74704 | GNG8 | 94235 | 4 | 1 | 15 | |
| TCGA | GNG8 | 94235 | 14 | 16 | 66 |
Total number of gains: 116; Total number of losses: 67; Total Number of normals: 305.
Somatic mutations of GNG8:
Generating mutation plots.
Highly correlated genes for GNG8:
Showing top 20/185 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GNG8 | SIM1 | 0.731854 | 3 | 0 | 3 |
| GNG8 | KRTAP10-12 | 0.728438 | 3 | 0 | 3 |
| GNG8 | FAM186A | 0.725005 | 3 | 0 | 3 |
| GNG8 | TMEM179 | 0.697179 | 3 | 0 | 3 |
| GNG8 | RGS9 | 0.695258 | 3 | 0 | 3 |
| GNG8 | SLC26A1 | 0.692139 | 4 | 0 | 4 |
| GNG8 | KRTAP5-7 | 0.690862 | 3 | 0 | 3 |
| GNG8 | FAM222A-AS1 | 0.690071 | 4 | 0 | 4 |
| GNG8 | TRIML2 | 0.689828 | 3 | 0 | 3 |
| GNG8 | LIPE-AS1 | 0.688299 | 3 | 0 | 3 |
| GNG8 | PROCA1 | 0.6866 | 4 | 0 | 3 |
| GNG8 | EFCAB13 | 0.684244 | 3 | 0 | 3 |
| GNG8 | ADAMTS19 | 0.68089 | 3 | 0 | 3 |
| GNG8 | LHCGR | 0.679791 | 3 | 0 | 3 |
| GNG8 | ZNF667 | 0.677312 | 4 | 0 | 4 |
| GNG8 | GIPC3 | 0.676325 | 3 | 0 | 3 |
| GNG8 | SLC22A31 | 0.675649 | 4 | 0 | 3 |
| GNG8 | FAM131C | 0.673995 | 4 | 0 | 4 |
| GNG8 | CALY | 0.669087 | 5 | 0 | 5 |
| GNG8 | SSC5D | 0.666786 | 3 | 0 | 3 |
For details and further investigation, click here
