| Full name: actin binding LIM protein family member 3 | Alias Symbol: KIAA0843 | ||
| Type: protein-coding gene | Cytoband: 5q32 | ||
| Entrez ID: 22885 | HGNC ID: HGNC:29132 | Ensembl Gene: ENSG00000173210 | OMIM ID: 611305 |
| Drug and gene relationship at DGIdb | |||
ABLIM3 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04360 | Axon guidance |
Expression of ABLIM3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ABLIM3 | 22885 | 205730_s_at | -1.8183 | 0.0058 | |
| GSE20347 | ABLIM3 | 22885 | 205730_s_at | -2.0439 | 0.0000 | |
| GSE23400 | ABLIM3 | 22885 | 205730_s_at | -1.5957 | 0.0000 | |
| GSE26886 | ABLIM3 | 22885 | 205730_s_at | -2.7356 | 0.0000 | |
| GSE29001 | ABLIM3 | 22885 | 205730_s_at | -2.7638 | 0.0000 | |
| GSE38129 | ABLIM3 | 22885 | 205730_s_at | -2.1178 | 0.0000 | |
| GSE45670 | ABLIM3 | 22885 | 205730_s_at | -1.4239 | 0.0014 | |
| GSE53622 | ABLIM3 | 22885 | 90130 | -2.7065 | 0.0000 | |
| GSE53624 | ABLIM3 | 22885 | 65109 | -2.5958 | 0.0000 | |
| GSE63941 | ABLIM3 | 22885 | 205730_s_at | -2.5030 | 0.0043 | |
| GSE77861 | ABLIM3 | 22885 | 205730_s_at | -1.1679 | 0.0174 | |
| GSE97050 | ABLIM3 | 22885 | A_23_P256205 | -0.9265 | 0.1378 | |
| SRP007169 | ABLIM3 | 22885 | RNAseq | -5.5836 | 0.0000 | |
| SRP008496 | ABLIM3 | 22885 | RNAseq | -5.0971 | 0.0000 | |
| SRP064894 | ABLIM3 | 22885 | RNAseq | -2.7077 | 0.0000 | |
| SRP133303 | ABLIM3 | 22885 | RNAseq | -2.3746 | 0.0000 | |
| SRP159526 | ABLIM3 | 22885 | RNAseq | -3.3825 | 0.0000 | |
| SRP193095 | ABLIM3 | 22885 | RNAseq | -3.1622 | 0.0000 | |
| SRP219564 | ABLIM3 | 22885 | RNAseq | -1.8383 | 0.0024 | |
| TCGA | ABLIM3 | 22885 | RNAseq | -0.4648 | 0.0064 |
Upregulated datasets: 0; Downregulated datasets: 18.
Survival by ABLIM3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ABLIM3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ABLIM3 | 22885 | 1 | 12 | 17 | |
| GSE20123 | ABLIM3 | 22885 | 1 | 12 | 17 | |
| GSE43470 | ABLIM3 | 22885 | 2 | 10 | 31 | |
| GSE46452 | ABLIM3 | 22885 | 0 | 27 | 32 | |
| GSE47630 | ABLIM3 | 22885 | 0 | 20 | 20 | |
| GSE54993 | ABLIM3 | 22885 | 9 | 1 | 60 | |
| GSE54994 | ABLIM3 | 22885 | 2 | 15 | 36 | |
| GSE60625 | ABLIM3 | 22885 | 0 | 0 | 11 | |
| GSE74703 | ABLIM3 | 22885 | 2 | 7 | 27 | |
| GSE74704 | ABLIM3 | 22885 | 1 | 7 | 12 | |
| TCGA | ABLIM3 | 22885 | 5 | 38 | 53 |
Total number of gains: 23; Total number of losses: 149; Total Number of normals: 316.
Somatic mutations of ABLIM3:
Generating mutation plots.
Highly correlated genes for ABLIM3:
Showing top 20/750 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ABLIM3 | KRT78 | 0.881275 | 6 | 0 | 6 |
| ABLIM3 | SPNS2 | 0.875355 | 4 | 0 | 4 |
| ABLIM3 | SH3BGRL2 | 0.871691 | 6 | 0 | 6 |
| ABLIM3 | CRISP3 | 0.868089 | 10 | 0 | 10 |
| ABLIM3 | FAM163B | 0.867417 | 3 | 0 | 3 |
| ABLIM3 | UBL3 | 0.859195 | 10 | 0 | 10 |
| ABLIM3 | GYS2 | 0.854226 | 10 | 0 | 10 |
| ABLIM3 | ENDOU | 0.84757 | 10 | 0 | 10 |
| ABLIM3 | PPP1R3C | 0.844049 | 11 | 0 | 11 |
| ABLIM3 | GDPD3 | 0.843745 | 10 | 0 | 10 |
| ABLIM3 | ARHGAP10 | 0.843483 | 11 | 0 | 11 |
| ABLIM3 | ATG9B | 0.841793 | 6 | 0 | 6 |
| ABLIM3 | FAM3D | 0.8406 | 6 | 0 | 6 |
| ABLIM3 | EPS8L1 | 0.839438 | 10 | 0 | 10 |
| ABLIM3 | CYSRT1 | 0.834557 | 6 | 0 | 6 |
| ABLIM3 | SFTA2 | 0.833082 | 4 | 0 | 4 |
| ABLIM3 | SPINK7 | 0.83294 | 7 | 0 | 7 |
| ABLIM3 | PSCA | 0.832533 | 8 | 0 | 8 |
| ABLIM3 | RAET1E | 0.830565 | 7 | 0 | 7 |
| ABLIM3 | KRTAP20-1 | 0.829281 | 3 | 0 | 3 |
For details and further investigation, click here
