| Full name: interleukin 17B | Alias Symbol: IL-17B|ZCYTO7|IL-20|MGC138900|MGC138901|NIRF | ||
| Type: protein-coding gene | Cytoband: 5q32 | ||
| Entrez ID: 27190 | HGNC ID: HGNC:5982 | Ensembl Gene: ENSG00000127743 | OMIM ID: 604627 |
| Drug and gene relationship at DGIdb | |||
Expression of IL17B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IL17B | 27190 | 220273_at | -0.3752 | 0.2533 | |
| GSE20347 | IL17B | 27190 | 220273_at | -0.0250 | 0.7609 | |
| GSE23400 | IL17B | 27190 | 220273_at | -0.1114 | 0.0010 | |
| GSE26886 | IL17B | 27190 | 220273_at | 0.3761 | 0.0197 | |
| GSE29001 | IL17B | 27190 | 220273_at | 0.0569 | 0.5713 | |
| GSE38129 | IL17B | 27190 | 220273_at | -0.2076 | 0.0116 | |
| GSE45670 | IL17B | 27190 | 220273_at | -0.2142 | 0.0526 | |
| GSE53622 | IL17B | 27190 | 4162 | -0.8306 | 0.0000 | |
| GSE53624 | IL17B | 27190 | 4162 | -0.9389 | 0.0000 | |
| GSE63941 | IL17B | 27190 | 220273_at | 0.0161 | 0.9575 | |
| GSE77861 | IL17B | 27190 | 220273_at | -0.0235 | 0.9219 | |
| GSE97050 | IL17B | 27190 | A_23_P167479 | -0.3800 | 0.4659 | |
| SRP159526 | IL17B | 27190 | RNAseq | -1.4632 | 0.0450 | |
| SRP219564 | IL17B | 27190 | RNAseq | -0.3828 | 0.7071 | |
| TCGA | IL17B | 27190 | RNAseq | -1.0536 | 0.0363 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by IL17B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IL17B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IL17B | 27190 | 1 | 12 | 17 | |
| GSE20123 | IL17B | 27190 | 1 | 12 | 17 | |
| GSE43470 | IL17B | 27190 | 2 | 10 | 31 | |
| GSE46452 | IL17B | 27190 | 0 | 27 | 32 | |
| GSE47630 | IL17B | 27190 | 0 | 20 | 20 | |
| GSE54993 | IL17B | 27190 | 9 | 1 | 60 | |
| GSE54994 | IL17B | 27190 | 2 | 15 | 36 | |
| GSE60625 | IL17B | 27190 | 0 | 0 | 11 | |
| GSE74703 | IL17B | 27190 | 2 | 7 | 27 | |
| GSE74704 | IL17B | 27190 | 1 | 7 | 12 | |
| TCGA | IL17B | 27190 | 6 | 38 | 52 |
Total number of gains: 24; Total number of losses: 149; Total Number of normals: 315.
Somatic mutations of IL17B:
Generating mutation plots.
Highly correlated genes for IL17B:
Showing top 20/384 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IL17B | HMCN2 | 0.812793 | 3 | 0 | 3 |
| IL17B | GIPC3 | 0.782884 | 3 | 0 | 3 |
| IL17B | SMIM10 | 0.748375 | 3 | 0 | 3 |
| IL17B | PGR | 0.746451 | 3 | 0 | 3 |
| IL17B | ZNF385D | 0.745868 | 4 | 0 | 4 |
| IL17B | JSRP1 | 0.735559 | 3 | 0 | 3 |
| IL17B | PTCHD1 | 0.730578 | 3 | 0 | 3 |
| IL17B | C19orf81 | 0.725569 | 3 | 0 | 3 |
| IL17B | ADAMTS19 | 0.71422 | 3 | 0 | 3 |
| IL17B | FBXO44 | 0.712521 | 3 | 0 | 3 |
| IL17B | LAT | 0.711123 | 4 | 0 | 4 |
| IL17B | RSPO1 | 0.700994 | 4 | 0 | 4 |
| IL17B | TBXA2R | 0.699968 | 5 | 0 | 5 |
| IL17B | MGAT5B | 0.699022 | 3 | 0 | 3 |
| IL17B | UPK3A | 0.697926 | 3 | 0 | 3 |
| IL17B | ANKS1B | 0.693373 | 3 | 0 | 3 |
| IL17B | ARHGAP6 | 0.692491 | 5 | 0 | 4 |
| IL17B | PRRT2 | 0.691702 | 4 | 0 | 3 |
| IL17B | HMGCLL1 | 0.687313 | 4 | 0 | 4 |
| IL17B | PPP1R12C | 0.686394 | 7 | 0 | 7 |
For details and further investigation, click here
