| Full name: lin-37 DREAM MuvB core complex component | Alias Symbol: ZK418.4|F25965|lin-37 | ||
| Type: protein-coding gene | Cytoband: 19q13.12 | ||
| Entrez ID: 55957 | HGNC ID: HGNC:33234 | Ensembl Gene: ENSG00000267796 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of LIN37:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LIN37 | 55957 | 213526_s_at | 0.1948 | 0.7341 | |
| GSE20347 | LIN37 | 55957 | 213526_s_at | -0.1942 | 0.3575 | |
| GSE23400 | LIN37 | 55957 | 213526_s_at | 0.0870 | 0.0843 | |
| GSE26886 | LIN37 | 55957 | 232534_at | 0.2175 | 0.0631 | |
| GSE29001 | LIN37 | 55957 | 213526_s_at | 0.2495 | 0.5710 | |
| GSE38129 | LIN37 | 55957 | 213526_s_at | -0.1446 | 0.4438 | |
| GSE45670 | LIN37 | 55957 | 213526_s_at | 0.2614 | 0.1283 | |
| GSE63941 | LIN37 | 55957 | 213526_s_at | 0.0985 | 0.9116 | |
| GSE77861 | LIN37 | 55957 | 232534_at | 0.0001 | 0.9995 | |
| GSE97050 | LIN37 | 55957 | A_23_P165186 | 0.0365 | 0.8757 | |
| SRP007169 | LIN37 | 55957 | RNAseq | 0.5055 | 0.4244 | |
| SRP064894 | LIN37 | 55957 | RNAseq | 0.7265 | 0.0098 | |
| SRP133303 | LIN37 | 55957 | RNAseq | 0.2273 | 0.3566 | |
| SRP159526 | LIN37 | 55957 | RNAseq | 0.1880 | 0.6100 | |
| SRP193095 | LIN37 | 55957 | RNAseq | 0.1197 | 0.2321 | |
| SRP219564 | LIN37 | 55957 | RNAseq | 0.0224 | 0.9294 | |
| TCGA | LIN37 | 55957 | RNAseq | 0.1669 | 0.0555 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LIN37 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of LIN37:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LIN37 | 55957 | 7 | 4 | 19 | |
| GSE20123 | LIN37 | 55957 | 7 | 3 | 20 | |
| GSE43470 | LIN37 | 55957 | 3 | 7 | 33 | |
| GSE46452 | LIN37 | 55957 | 48 | 1 | 10 | |
| GSE47630 | LIN37 | 55957 | 9 | 5 | 26 | |
| GSE54993 | LIN37 | 55957 | 17 | 3 | 50 | |
| GSE54994 | LIN37 | 55957 | 6 | 9 | 38 | |
| GSE60625 | LIN37 | 55957 | 9 | 0 | 2 | |
| GSE74703 | LIN37 | 55957 | 3 | 4 | 29 | |
| GSE74704 | LIN37 | 55957 | 6 | 1 | 13 | |
| TCGA | LIN37 | 55957 | 22 | 10 | 64 |
Total number of gains: 137; Total number of losses: 47; Total Number of normals: 304.
Somatic mutations of LIN37:
Generating mutation plots.
Highly correlated genes for LIN37:
Showing top 20/256 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LIN37 | NFAM1 | 0.78236 | 3 | 0 | 3 |
| LIN37 | EVI5L | 0.778672 | 3 | 0 | 3 |
| LIN37 | MNT | 0.773608 | 3 | 0 | 3 |
| LIN37 | IL3RA | 0.762792 | 3 | 0 | 3 |
| LIN37 | RNF31 | 0.745544 | 3 | 0 | 3 |
| LIN37 | GDF11 | 0.73797 | 3 | 0 | 3 |
| LIN37 | COL13A1 | 0.737095 | 3 | 0 | 3 |
| LIN37 | PLIN4 | 0.73046 | 3 | 0 | 3 |
| LIN37 | ALKBH6 | 0.729227 | 5 | 0 | 5 |
| LIN37 | SIK1 | 0.723911 | 3 | 0 | 3 |
| LIN37 | EGLN2 | 0.720492 | 3 | 0 | 3 |
| LIN37 | PDE3A | 0.718366 | 3 | 0 | 3 |
| LIN37 | SLC2A4RG | 0.71526 | 4 | 0 | 4 |
| LIN37 | ABCD4 | 0.712665 | 3 | 0 | 3 |
| LIN37 | LIMD2 | 0.70916 | 3 | 0 | 3 |
| LIN37 | SSC5D | 0.703627 | 3 | 0 | 3 |
| LIN37 | CLMP | 0.699007 | 3 | 0 | 3 |
| LIN37 | PROSER3 | 0.698568 | 3 | 0 | 3 |
| LIN37 | CPT1C | 0.698061 | 4 | 0 | 3 |
| LIN37 | ZNF579 | 0.694536 | 4 | 0 | 4 |
For details and further investigation, click here
