SH3PXD2B

 

Full name: SH3 and PX domains 2B Alias Symbol: FLJ20831
Type: protein-coding gene Cytoband: 5q35.1
Entrez ID: 285590 HGNC ID: HGNC:29242 Ensembl Gene: ENSG00000174705 OMIM ID: 613293
Drug and gene relationship at DGIdb

 

Expression of SH3PXD2B:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SH3PXD2B 285590 231823_s_at 0.7492 0.1230
GSE26886 SH3PXD2B 285590 231823_s_at 0.7568 0.0001
GSE45670 SH3PXD2B 285590 231823_s_at 0.6471 0.0041
GSE53622 SH3PXD2B 285590 92229 1.1287 0.0000
GSE53624 SH3PXD2B 285590 92229 1.2556 0.0000
GSE63941 SH3PXD2B 285590 231823_s_at -1.3004 0.0131
GSE77861 SH3PXD2B 285590 231823_s_at 0.9310 0.0184
GSE97050 SH3PXD2B 285590 A_32_P24585 0.7771 0.0841
SRP007169 SH3PXD2B 285590 RNAseq 2.6654 0.0000
SRP008496 SH3PXD2B 285590 RNAseq 2.7149 0.0000
SRP064894 SH3PXD2B 285590 RNAseq 1.2033 0.0001
SRP133303 SH3PXD2B 285590 RNAseq 1.3709 0.0000
SRP159526 SH3PXD2B 285590 RNAseq 0.5134 0.0601
SRP193095 SH3PXD2B 285590 RNAseq 1.6992 0.0000
SRP219564 SH3PXD2B 285590 RNAseq 0.7459 0.0087
TCGA SH3PXD2B 285590 RNAseq 0.0459 0.4893

Upregulated datasets: 7; Downregulated datasets: 1.  

 

Survival by SH3PXD2B expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of SH3PXD2B:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SH3PXD2B 285590 2 13 15
GSE20123 SH3PXD2B 285590 2 13 15
GSE43470 SH3PXD2B 285590 1 10 32
GSE46452 SH3PXD2B 285590 0 27 32
GSE47630 SH3PXD2B 285590 0 20 20
GSE54993 SH3PXD2B 285590 9 2 59
GSE54994 SH3PXD2B 285590 2 15 36
GSE60625 SH3PXD2B 285590 1 0 10
GSE74703 SH3PXD2B 285590 1 7 28
GSE74704 SH3PXD2B 285590 1 6 13
TCGA SH3PXD2B 285590 8 34 54

Total number of gains: 27; Total number of losses: 147; Total Number of normals: 314.  

 

Somatic mutations of SH3PXD2B:

 

Generating mutation plots.

 

Highly correlated genes for SH3PXD2B:

 

Showing top 20/1620 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SH3PXD2BLRRC8C0.797296303
SH3PXD2BWDR540.771134707
SH3PXD2BFADS10.770066303
SH3PXD2BTMEM184B0.767677707
SH3PXD2BXPR10.76762707
SH3PXD2BRAB340.765752303
SH3PXD2BCOL5A20.760482808
SH3PXD2BGALNT180.756476606
SH3PXD2BCOL5A10.751428808
SH3PXD2BCEBPB0.750765707
SH3PXD2BPSMB20.745671707
SH3PXD2BCRLF10.740605303
SH3PXD2BFCGR3A0.737209303
SH3PXD2BARPC1B0.736518807
SH3PXD2BPYCR20.73567303
SH3PXD2BPLAUR0.735456707
SH3PXD2BGALNT100.7345605
SH3PXD2BSPON20.733473403
SH3PXD2BFMNL20.729846707
SH3PXD2BTEAD40.728757707

For details and further investigation, click here