| Full name: chromosome 4 open reading frame 48 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 4p16.3 | ||
| Entrez ID: 401115 | HGNC ID: HGNC:34437 | Ensembl Gene: ENSG00000243449 | OMIM ID: 614690 |
| Drug and gene relationship at DGIdb | |||
Expression of C4orf48:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C4orf48 | 401115 | 229860_x_at | 1.6280 | 0.0562 | |
| GSE26886 | C4orf48 | 401115 | 229860_x_at | 2.4272 | 0.0000 | |
| GSE45670 | C4orf48 | 401115 | 229860_x_at | 1.5907 | 0.0000 | |
| GSE53622 | C4orf48 | 401115 | 34533 | 0.8966 | 0.0000 | |
| GSE53624 | C4orf48 | 401115 | 34533 | 1.3765 | 0.0000 | |
| GSE63941 | C4orf48 | 401115 | 229860_x_at | -0.8998 | 0.0835 | |
| GSE77861 | C4orf48 | 401115 | 229860_x_at | 1.2154 | 0.0010 | |
| GSE97050 | C4orf48 | 401115 | A_32_P90047 | 0.3191 | 0.2515 | |
| SRP007169 | C4orf48 | 401115 | RNAseq | 2.6415 | 0.0111 | |
| SRP064894 | C4orf48 | 401115 | RNAseq | 4.3217 | 0.0000 | |
| SRP133303 | C4orf48 | 401115 | RNAseq | 1.7140 | 0.0000 | |
| SRP159526 | C4orf48 | 401115 | RNAseq | 2.4617 | 0.0000 | |
| SRP219564 | C4orf48 | 401115 | RNAseq | 2.3726 | 0.0000 | |
| TCGA | C4orf48 | 401115 | RNAseq | 0.2231 | 0.1700 |
Upregulated datasets: 9; Downregulated datasets: 0.
Survival by C4orf48 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C4orf48:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C4orf48 | 401115 | 0 | 16 | 14 | |
| GSE20123 | C4orf48 | 401115 | 0 | 16 | 14 | |
| GSE43470 | C4orf48 | 401115 | 0 | 17 | 26 | |
| GSE46452 | C4orf48 | 401115 | 1 | 36 | 22 | |
| GSE47630 | C4orf48 | 401115 | 1 | 19 | 20 | |
| GSE54993 | C4orf48 | 401115 | 11 | 0 | 59 | |
| GSE54994 | C4orf48 | 401115 | 3 | 12 | 38 | |
| GSE60625 | C4orf48 | 401115 | 0 | 0 | 11 | |
| GSE74703 | C4orf48 | 401115 | 0 | 13 | 23 | |
| GSE74704 | C4orf48 | 401115 | 0 | 8 | 12 | |
| TCGA | C4orf48 | 401115 | 9 | 47 | 40 |
Total number of gains: 25; Total number of losses: 184; Total Number of normals: 279.
Somatic mutations of C4orf48:
Generating mutation plots.
Highly correlated genes for C4orf48:
Showing top 20/1433 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C4orf48 | MMP1 | 0.790847 | 7 | 0 | 7 |
| C4orf48 | TTYH3 | 0.780418 | 7 | 0 | 7 |
| C4orf48 | SLC19A1 | 0.757842 | 3 | 0 | 3 |
| C4orf48 | MFAP2 | 0.754929 | 7 | 0 | 7 |
| C4orf48 | COLGALT1 | 0.752151 | 6 | 0 | 6 |
| C4orf48 | SPP1 | 0.749962 | 7 | 0 | 7 |
| C4orf48 | IGF2BP2 | 0.748054 | 7 | 0 | 7 |
| C4orf48 | PDIA5 | 0.746088 | 3 | 0 | 3 |
| C4orf48 | ZBED1 | 0.737643 | 3 | 0 | 3 |
| C4orf48 | PTK7 | 0.735771 | 7 | 0 | 7 |
| C4orf48 | AGRN | 0.735182 | 7 | 0 | 7 |
| C4orf48 | TRIP13 | 0.734862 | 7 | 0 | 7 |
| C4orf48 | PLAU | 0.730182 | 7 | 0 | 7 |
| C4orf48 | ACLY | 0.727732 | 8 | 0 | 7 |
| C4orf48 | STRADA | 0.727412 | 3 | 0 | 3 |
| C4orf48 | TMEM184B | 0.727113 | 7 | 0 | 7 |
| C4orf48 | TGFBI | 0.727067 | 7 | 0 | 7 |
| C4orf48 | XPR1 | 0.726814 | 7 | 0 | 7 |
| C4orf48 | MYO10 | 0.726649 | 4 | 0 | 4 |
| C4orf48 | FMNL2 | 0.72611 | 7 | 0 | 7 |
For details and further investigation, click here
