C4orf48

 

Full name: chromosome 4 open reading frame 48 Alias Symbol: 
Type: protein-coding gene Cytoband: 4p16.3
Entrez ID: 401115 HGNC ID: HGNC:34437 Ensembl Gene: ENSG00000243449 OMIM ID: 614690
Drug and gene relationship at DGIdb

 

Expression of C4orf48:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 C4orf48 401115 229860_x_at 1.6280 0.0562
GSE26886 C4orf48 401115 229860_x_at 2.4272 0.0000
GSE45670 C4orf48 401115 229860_x_at 1.5907 0.0000
GSE53622 C4orf48 401115 34533 0.8966 0.0000
GSE53624 C4orf48 401115 34533 1.3765 0.0000
GSE63941 C4orf48 401115 229860_x_at -0.8998 0.0835
GSE77861 C4orf48 401115 229860_x_at 1.2154 0.0010
GSE97050 C4orf48 401115 A_32_P90047 0.3191 0.2515
SRP007169 C4orf48 401115 RNAseq 2.6415 0.0111
SRP064894 C4orf48 401115 RNAseq 4.3217 0.0000
SRP133303 C4orf48 401115 RNAseq 1.7140 0.0000
SRP159526 C4orf48 401115 RNAseq 2.4617 0.0000
SRP219564 C4orf48 401115 RNAseq 2.3726 0.0000
TCGA C4orf48 401115 RNAseq 0.2231 0.1700

Upregulated datasets: 9; Downregulated datasets: 0.  


 

Survival by C4orf48 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of C4orf48:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 C4orf48 401115 0 16 14
GSE20123 C4orf48 401115 0 16 14
GSE43470 C4orf48 401115 0 17 26
GSE46452 C4orf48 401115 1 36 22
GSE47630 C4orf48 401115 1 19 20
GSE54993 C4orf48 401115 11 0 59
GSE54994 C4orf48 401115 3 12 38
GSE60625 C4orf48 401115 0 0 11
GSE74703 C4orf48 401115 0 13 23
GSE74704 C4orf48 401115 0 8 12
TCGA C4orf48 401115 9 47 40

Total number of gains: 25; Total number of losses: 184; Total Number of normals: 279.  


 

Somatic mutations of C4orf48:

 

Generating mutation plots.

 

Highly correlated genes for C4orf48:

 

Showing top 20/1433 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
C4orf48MMP10.790847707
C4orf48TTYH30.780418707
C4orf48SLC19A10.757842303
C4orf48MFAP20.754929707
C4orf48COLGALT10.752151606
C4orf48SPP10.749962707
C4orf48IGF2BP20.748054707
C4orf48PDIA50.746088303
C4orf48ZBED10.737643303
C4orf48PTK70.735771707
C4orf48AGRN0.735182707
C4orf48TRIP130.734862707
C4orf48PLAU0.730182707
C4orf48ACLY0.727732807
C4orf48STRADA0.727412303
C4orf48TMEM184B0.727113707
C4orf48TGFBI0.727067707
C4orf48XPR10.726814707
C4orf48MYO100.726649404
C4orf48FMNL20.72611707

For details and further investigation, click here