| Full name: myelin protein zero like 1 | Alias Symbol: PZR|FLJ21047 | ||
| Type: protein-coding gene | Cytoband: 1q24.2 | ||
| Entrez ID: 9019 | HGNC ID: HGNC:7226 | Ensembl Gene: ENSG00000197965 | OMIM ID: 604376 |
| Drug and gene relationship at DGIdb | |||
Expression of MPZL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MPZL1 | 9019 | 201874_at | 0.3211 | 0.2310 | |
| GSE20347 | MPZL1 | 9019 | 201874_at | 0.1685 | 0.3599 | |
| GSE23400 | MPZL1 | 9019 | 201874_at | 0.3396 | 0.0000 | |
| GSE26886 | MPZL1 | 9019 | 201874_at | 0.1111 | 0.6088 | |
| GSE29001 | MPZL1 | 9019 | 210210_at | 0.3740 | 0.1157 | |
| GSE38129 | MPZL1 | 9019 | 201874_at | 0.2097 | 0.0980 | |
| GSE45670 | MPZL1 | 9019 | 201874_at | 0.2821 | 0.1399 | |
| GSE53622 | MPZL1 | 9019 | 20996 | 0.4382 | 0.0000 | |
| GSE53624 | MPZL1 | 9019 | 76079 | 0.5164 | 0.0000 | |
| GSE63941 | MPZL1 | 9019 | 201874_at | -0.5565 | 0.0862 | |
| GSE77861 | MPZL1 | 9019 | 201874_at | 0.2620 | 0.3065 | |
| GSE97050 | MPZL1 | 9019 | A_33_P3215953 | 0.3636 | 0.2223 | |
| SRP007169 | MPZL1 | 9019 | RNAseq | 0.1171 | 0.7078 | |
| SRP008496 | MPZL1 | 9019 | RNAseq | 0.6062 | 0.0250 | |
| SRP064894 | MPZL1 | 9019 | RNAseq | 0.5006 | 0.0008 | |
| SRP133303 | MPZL1 | 9019 | RNAseq | 0.5204 | 0.0038 | |
| SRP159526 | MPZL1 | 9019 | RNAseq | 0.3453 | 0.1607 | |
| SRP193095 | MPZL1 | 9019 | RNAseq | 0.3590 | 0.0012 | |
| SRP219564 | MPZL1 | 9019 | RNAseq | 0.5538 | 0.0650 | |
| TCGA | MPZL1 | 9019 | RNAseq | 0.0437 | 0.2927 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MPZL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MPZL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MPZL1 | 9019 | 11 | 1 | 18 | |
| GSE20123 | MPZL1 | 9019 | 11 | 1 | 18 | |
| GSE43470 | MPZL1 | 9019 | 7 | 2 | 34 | |
| GSE46452 | MPZL1 | 9019 | 3 | 1 | 55 | |
| GSE47630 | MPZL1 | 9019 | 14 | 0 | 26 | |
| GSE54993 | MPZL1 | 9019 | 0 | 6 | 64 | |
| GSE54994 | MPZL1 | 9019 | 16 | 0 | 37 | |
| GSE60625 | MPZL1 | 9019 | 0 | 0 | 11 | |
| GSE74703 | MPZL1 | 9019 | 7 | 2 | 27 | |
| GSE74704 | MPZL1 | 9019 | 5 | 0 | 15 | |
| TCGA | MPZL1 | 9019 | 44 | 3 | 49 |
Total number of gains: 118; Total number of losses: 16; Total Number of normals: 354.
Somatic mutations of MPZL1:
Generating mutation plots.
Highly correlated genes for MPZL1:
Showing top 20/776 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MPZL1 | ADAMTSL2 | 0.738271 | 3 | 0 | 3 |
| MPZL1 | CEP170 | 0.719841 | 3 | 0 | 3 |
| MPZL1 | AFAP1L2 | 0.7092 | 3 | 0 | 3 |
| MPZL1 | RAB34 | 0.707187 | 3 | 0 | 3 |
| MPZL1 | SS18L1 | 0.704274 | 3 | 0 | 3 |
| MPZL1 | SPON2 | 0.701641 | 3 | 0 | 3 |
| MPZL1 | NEIL2 | 0.691062 | 3 | 0 | 3 |
| MPZL1 | ETS1 | 0.684544 | 3 | 0 | 3 |
| MPZL1 | LRRC8C | 0.682169 | 3 | 0 | 3 |
| MPZL1 | PIM2 | 0.679172 | 3 | 0 | 3 |
| MPZL1 | CNIH4 | 0.67476 | 7 | 0 | 7 |
| MPZL1 | SLC39A13 | 0.674163 | 5 | 0 | 5 |
| MPZL1 | FADS1 | 0.668636 | 3 | 0 | 3 |
| MPZL1 | SAAL1 | 0.668394 | 4 | 0 | 3 |
| MPZL1 | FAR2 | 0.665563 | 3 | 0 | 3 |
| MPZL1 | XPR1 | 0.665158 | 6 | 0 | 5 |
| MPZL1 | CUX1 | 0.664922 | 4 | 0 | 4 |
| MPZL1 | ZNF275 | 0.664002 | 3 | 0 | 3 |
| MPZL1 | PDIA5 | 0.661585 | 3 | 0 | 3 |
| MPZL1 | LAPTM4B | 0.658362 | 6 | 0 | 5 |
For details and further investigation, click here
