| Full name: ADAMTS like 3 | Alias Symbol: KIAA1233|punctin-2 | ||
| Type: protein-coding gene | Cytoband: 15q25.2 | ||
| Entrez ID: 57188 | HGNC ID: HGNC:14633 | Ensembl Gene: ENSG00000156218 | OMIM ID: 609199 |
| Drug and gene relationship at DGIdb | |||
Expression of ADAMTSL3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ADAMTSL3 | 57188 | 213974_at | -1.5258 | 0.3872 | |
| GSE20347 | ADAMTSL3 | 57188 | 213974_at | -0.1356 | 0.2568 | |
| GSE23400 | ADAMTSL3 | 57188 | 213974_at | -0.5791 | 0.0000 | |
| GSE26886 | ADAMTSL3 | 57188 | 1559748_at | 0.0663 | 0.6099 | |
| GSE29001 | ADAMTSL3 | 57188 | 213974_at | -0.3221 | 0.2436 | |
| GSE38129 | ADAMTSL3 | 57188 | 213974_at | -1.0264 | 0.0112 | |
| GSE45670 | ADAMTSL3 | 57188 | 1559748_at | 0.0064 | 0.9514 | |
| GSE53622 | ADAMTSL3 | 57188 | 138034 | -1.2740 | 0.0000 | |
| GSE53624 | ADAMTSL3 | 57188 | 138034 | -1.2107 | 0.0000 | |
| GSE63941 | ADAMTSL3 | 57188 | 1559748_at | 0.2606 | 0.4550 | |
| GSE77861 | ADAMTSL3 | 57188 | 1559748_at | -0.0321 | 0.6812 | |
| GSE97050 | ADAMTSL3 | 57188 | A_23_P308974 | -0.6621 | 0.3138 | |
| SRP064894 | ADAMTSL3 | 57188 | RNAseq | -1.1160 | 0.0247 | |
| SRP133303 | ADAMTSL3 | 57188 | RNAseq | -0.6224 | 0.4232 | |
| SRP159526 | ADAMTSL3 | 57188 | RNAseq | -0.4944 | 0.2786 | |
| SRP219564 | ADAMTSL3 | 57188 | RNAseq | -0.3452 | 0.7578 | |
| TCGA | ADAMTSL3 | 57188 | RNAseq | -1.2903 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by ADAMTSL3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ADAMTSL3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ADAMTSL3 | 57188 | 8 | 0 | 22 | |
| GSE20123 | ADAMTSL3 | 57188 | 8 | 0 | 22 | |
| GSE43470 | ADAMTSL3 | 57188 | 4 | 4 | 35 | |
| GSE46452 | ADAMTSL3 | 57188 | 3 | 7 | 49 | |
| GSE47630 | ADAMTSL3 | 57188 | 8 | 10 | 22 | |
| GSE54993 | ADAMTSL3 | 57188 | 5 | 6 | 59 | |
| GSE54994 | ADAMTSL3 | 57188 | 6 | 6 | 41 | |
| GSE60625 | ADAMTSL3 | 57188 | 4 | 0 | 7 | |
| GSE74703 | ADAMTSL3 | 57188 | 4 | 2 | 30 | |
| GSE74704 | ADAMTSL3 | 57188 | 4 | 0 | 16 | |
| TCGA | ADAMTSL3 | 57188 | 17 | 14 | 65 |
Total number of gains: 71; Total number of losses: 49; Total Number of normals: 368.
Somatic mutations of ADAMTSL3:
Generating mutation plots.
Highly correlated genes for ADAMTSL3:
Showing top 20/501 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ADAMTSL3 | ITGB1BP2 | 0.837969 | 5 | 0 | 5 |
| ADAMTSL3 | ARHGAP6 | 0.809018 | 7 | 0 | 7 |
| ADAMTSL3 | PPP1R12B | 0.796701 | 7 | 0 | 7 |
| ADAMTSL3 | CHRDL1 | 0.795821 | 6 | 0 | 6 |
| ADAMTSL3 | SORCS1 | 0.792704 | 3 | 0 | 3 |
| ADAMTSL3 | ANGPTL1 | 0.788841 | 3 | 0 | 3 |
| ADAMTSL3 | MYOM1 | 0.785946 | 8 | 0 | 8 |
| ADAMTSL3 | ADAMTSL1 | 0.781444 | 4 | 0 | 4 |
| ADAMTSL3 | MAMDC2 | 0.780249 | 3 | 0 | 3 |
| ADAMTSL3 | MEOX2 | 0.775197 | 6 | 0 | 6 |
| ADAMTSL3 | OGN | 0.774979 | 7 | 0 | 6 |
| ADAMTSL3 | PDZRN4 | 0.771907 | 8 | 0 | 8 |
| ADAMTSL3 | DISP1 | 0.768741 | 4 | 0 | 4 |
| ADAMTSL3 | CYP2U1 | 0.768078 | 3 | 0 | 3 |
| ADAMTSL3 | PLP1 | 0.765407 | 7 | 0 | 6 |
| ADAMTSL3 | LMOD1 | 0.763952 | 7 | 0 | 7 |
| ADAMTSL3 | INPP5A | 0.763948 | 5 | 0 | 4 |
| ADAMTSL3 | C7 | 0.762827 | 7 | 0 | 7 |
| ADAMTSL3 | FGL2 | 0.756063 | 7 | 0 | 6 |
| ADAMTSL3 | SYNM | 0.750679 | 7 | 0 | 7 |
For details and further investigation, click here
