| Full name: mesenchyme homeobox 2 | Alias Symbol: MOX2 | ||
| Type: protein-coding gene | Cytoband: 7p21.2 | ||
| Entrez ID: 4223 | HGNC ID: HGNC:7014 | Ensembl Gene: ENSG00000106511 | OMIM ID: 600535 |
| Drug and gene relationship at DGIdb | |||
Expression of MEOX2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MEOX2 | 4223 | 206201_s_at | -0.9709 | 0.2807 | |
| GSE20347 | MEOX2 | 4223 | 206201_s_at | -0.3519 | 0.0231 | |
| GSE23400 | MEOX2 | 4223 | 206201_s_at | -0.1045 | 0.0339 | |
| GSE26886 | MEOX2 | 4223 | 206202_at | 0.0128 | 0.8985 | |
| GSE29001 | MEOX2 | 4223 | 206202_at | 0.0634 | 0.5847 | |
| GSE38129 | MEOX2 | 4223 | 206201_s_at | -0.9005 | 0.0157 | |
| GSE45670 | MEOX2 | 4223 | 206201_s_at | -2.5107 | 0.0000 | |
| GSE53622 | MEOX2 | 4223 | 32125 | -1.8522 | 0.0000 | |
| GSE53624 | MEOX2 | 4223 | 32125 | -1.4030 | 0.0000 | |
| GSE63941 | MEOX2 | 4223 | 206202_at | -0.0403 | 0.7264 | |
| GSE77861 | MEOX2 | 4223 | 206202_at | 0.0075 | 0.9243 | |
| GSE97050 | MEOX2 | 4223 | A_24_P106624 | -0.7486 | 0.1339 | |
| SRP064894 | MEOX2 | 4223 | RNAseq | 0.0804 | 0.8479 | |
| SRP133303 | MEOX2 | 4223 | RNAseq | -1.9286 | 0.0000 | |
| SRP159526 | MEOX2 | 4223 | RNAseq | 0.7011 | 0.2436 | |
| SRP219564 | MEOX2 | 4223 | RNAseq | 0.5405 | 0.5929 | |
| TCGA | MEOX2 | 4223 | RNAseq | -0.5017 | 0.1963 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by MEOX2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MEOX2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MEOX2 | 4223 | 14 | 2 | 14 | |
| GSE20123 | MEOX2 | 4223 | 14 | 2 | 14 | |
| GSE43470 | MEOX2 | 4223 | 5 | 0 | 38 | |
| GSE46452 | MEOX2 | 4223 | 11 | 1 | 47 | |
| GSE47630 | MEOX2 | 4223 | 9 | 1 | 30 | |
| GSE54993 | MEOX2 | 4223 | 0 | 6 | 64 | |
| GSE54994 | MEOX2 | 4223 | 21 | 1 | 31 | |
| GSE60625 | MEOX2 | 4223 | 0 | 0 | 11 | |
| GSE74703 | MEOX2 | 4223 | 5 | 0 | 31 | |
| GSE74704 | MEOX2 | 4223 | 8 | 2 | 10 | |
| TCGA | MEOX2 | 4223 | 56 | 5 | 35 |
Total number of gains: 143; Total number of losses: 20; Total Number of normals: 325.
Somatic mutations of MEOX2:
Generating mutation plots.
Highly correlated genes for MEOX2:
Showing top 20/1109 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MEOX2 | FIBIN | 0.862472 | 3 | 0 | 3 |
| MEOX2 | JAM2 | 0.854109 | 8 | 0 | 8 |
| MEOX2 | C1QTNF7 | 0.84345 | 5 | 0 | 5 |
| MEOX2 | OGN | 0.836156 | 9 | 0 | 8 |
| MEOX2 | PLN | 0.835537 | 8 | 0 | 8 |
| MEOX2 | AOC3 | 0.830423 | 8 | 0 | 8 |
| MEOX2 | SLIT2 | 0.828274 | 8 | 0 | 8 |
| MEOX2 | MRGPRF | 0.828076 | 5 | 0 | 5 |
| MEOX2 | SLIT3 | 0.82699 | 5 | 0 | 5 |
| MEOX2 | PDE1A | 0.82464 | 8 | 0 | 7 |
| MEOX2 | BHMT2 | 0.808765 | 8 | 0 | 8 |
| MEOX2 | EBF1 | 0.808091 | 5 | 0 | 5 |
| MEOX2 | RSPO3 | 0.79748 | 5 | 0 | 5 |
| MEOX2 | FGL2 | 0.797271 | 8 | 0 | 8 |
| MEOX2 | C3orf70 | 0.796546 | 5 | 0 | 5 |
| MEOX2 | TNFSF12 | 0.795052 | 3 | 0 | 3 |
| MEOX2 | CNN1 | 0.794963 | 6 | 0 | 6 |
| MEOX2 | JAM3 | 0.794411 | 8 | 0 | 8 |
| MEOX2 | C7 | 0.790881 | 8 | 0 | 7 |
| MEOX2 | CASQ2 | 0.790026 | 9 | 0 | 9 |
For details and further investigation, click here
