| Full name: synemin | Alias Symbol: KIAA0353|SYN | ||
| Type: protein-coding gene | Cytoband: 15q26.3 | ||
| Entrez ID: 23336 | HGNC ID: HGNC:24466 | Ensembl Gene: ENSG00000182253 | OMIM ID: 606087 |
| Drug and gene relationship at DGIdb | |||
Expression of SYNM:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SYNM | 23336 | 212730_at | -2.2793 | 0.1304 | |
| GSE20347 | SYNM | 23336 | 212730_at | -0.8350 | 0.1401 | |
| GSE23400 | SYNM | 23336 | 212730_at | -1.1822 | 0.0001 | |
| GSE26886 | SYNM | 23336 | 212730_at | 0.8449 | 0.1772 | |
| GSE29001 | SYNM | 23336 | 212730_at | -0.6119 | 0.4236 | |
| GSE38129 | SYNM | 23336 | 212730_at | -1.4581 | 0.0150 | |
| GSE45670 | SYNM | 23336 | 212730_at | -3.6378 | 0.0000 | |
| GSE53622 | SYNM | 23336 | 11269 | -2.5261 | 0.0000 | |
| GSE53624 | SYNM | 23336 | 11269 | -2.3985 | 0.0000 | |
| GSE63941 | SYNM | 23336 | 212730_at | 0.2424 | 0.8545 | |
| GSE77861 | SYNM | 23336 | 212730_at | 0.9152 | 0.0244 | |
| GSE97050 | SYNM | 23336 | A_24_P104407 | -2.7703 | 0.0835 | |
| SRP007169 | SYNM | 23336 | RNAseq | 1.9338 | 0.0162 | |
| SRP064894 | SYNM | 23336 | RNAseq | -0.6257 | 0.2355 | |
| SRP133303 | SYNM | 23336 | RNAseq | -2.6729 | 0.0000 | |
| SRP159526 | SYNM | 23336 | RNAseq | -0.9287 | 0.1475 | |
| SRP193095 | SYNM | 23336 | RNAseq | -0.1036 | 0.7448 | |
| SRP219564 | SYNM | 23336 | RNAseq | -0.8170 | 0.5229 | |
| TCGA | SYNM | 23336 | RNAseq | -0.6339 | 0.0007 |
Upregulated datasets: 1; Downregulated datasets: 6.
Survival by SYNM expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SYNM:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SYNM | 23336 | 7 | 1 | 22 | |
| GSE20123 | SYNM | 23336 | 7 | 1 | 22 | |
| GSE43470 | SYNM | 23336 | 8 | 3 | 32 | |
| GSE46452 | SYNM | 23336 | 3 | 7 | 49 | |
| GSE47630 | SYNM | 23336 | 9 | 10 | 21 | |
| GSE54993 | SYNM | 23336 | 4 | 7 | 59 | |
| GSE54994 | SYNM | 23336 | 9 | 7 | 37 | |
| GSE60625 | SYNM | 23336 | 4 | 0 | 7 | |
| GSE74703 | SYNM | 23336 | 6 | 3 | 27 | |
| GSE74704 | SYNM | 23336 | 3 | 2 | 15 | |
| TCGA | SYNM | 23336 | 19 | 12 | 65 |
Total number of gains: 79; Total number of losses: 53; Total Number of normals: 356.
Somatic mutations of SYNM:
Generating mutation plots.
Highly correlated genes for SYNM:
Showing top 20/931 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SYNM | LMOD1 | 0.879095 | 11 | 0 | 11 |
| SYNM | CNN1 | 0.850496 | 10 | 0 | 10 |
| SYNM | PPP1R12B | 0.841771 | 11 | 0 | 11 |
| SYNM | MYOCD | 0.838777 | 6 | 0 | 5 |
| SYNM | ACTG2 | 0.838445 | 12 | 0 | 12 |
| SYNM | NEGR1 | 0.837851 | 5 | 0 | 5 |
| SYNM | PLN | 0.833996 | 12 | 0 | 12 |
| SYNM | CYP21A2 | 0.824466 | 3 | 0 | 3 |
| SYNM | CHRDL1 | 0.821146 | 9 | 0 | 9 |
| SYNM | ACTBL2 | 0.81883 | 3 | 0 | 3 |
| SYNM | PCP4 | 0.817735 | 11 | 0 | 11 |
| SYNM | MYH11 | 0.815174 | 12 | 0 | 12 |
| SYNM | PYGM | 0.811364 | 9 | 0 | 9 |
| SYNM | FLNC | 0.810335 | 11 | 0 | 10 |
| SYNM | CASQ2 | 0.809333 | 11 | 0 | 10 |
| SYNM | PRUNE2 | 0.8091 | 12 | 0 | 11 |
| SYNM | ASB5 | 0.808464 | 6 | 0 | 5 |
| SYNM | PDZRN4 | 0.807843 | 9 | 0 | 9 |
| SYNM | CLEC3B | 0.806854 | 3 | 0 | 3 |
| SYNM | DES | 0.806782 | 12 | 0 | 11 |
For details and further investigation, click here
