| Full name: leiomodin 1 | Alias Symbol: 64kD|D1|1D | ||
| Type: protein-coding gene | Cytoband: 1q32.1 | ||
| Entrez ID: 25802 | HGNC ID: HGNC:6647 | Ensembl Gene: ENSG00000163431 | OMIM ID: 602715 |
| Drug and gene relationship at DGIdb | |||
Expression of LMOD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LMOD1 | 25802 | 203766_s_at | -2.3908 | 0.1577 | |
| GSE20347 | LMOD1 | 25802 | 203766_s_at | -0.9486 | 0.0224 | |
| GSE23400 | LMOD1 | 25802 | 203766_s_at | -1.3406 | 0.0000 | |
| GSE26886 | LMOD1 | 25802 | 203766_s_at | 0.4625 | 0.3344 | |
| GSE29001 | LMOD1 | 25802 | 203766_s_at | -1.0824 | 0.0043 | |
| GSE38129 | LMOD1 | 25802 | 203766_s_at | -1.6039 | 0.0034 | |
| GSE45670 | LMOD1 | 25802 | 203766_s_at | -3.2423 | 0.0000 | |
| GSE53622 | LMOD1 | 25802 | 17581 | -2.6615 | 0.0000 | |
| GSE53624 | LMOD1 | 25802 | 17581 | -2.5086 | 0.0000 | |
| GSE63941 | LMOD1 | 25802 | 203766_s_at | -2.5453 | 0.0000 | |
| GSE77861 | LMOD1 | 25802 | 203766_s_at | -0.0787 | 0.7697 | |
| GSE97050 | LMOD1 | 25802 | A_33_P3368879 | -1.9878 | 0.0620 | |
| SRP007169 | LMOD1 | 25802 | RNAseq | 2.1460 | 0.0023 | |
| SRP064894 | LMOD1 | 25802 | RNAseq | -0.4792 | 0.3432 | |
| SRP133303 | LMOD1 | 25802 | RNAseq | -2.8750 | 0.0000 | |
| SRP159526 | LMOD1 | 25802 | RNAseq | -1.7109 | 0.0307 | |
| SRP193095 | LMOD1 | 25802 | RNAseq | -0.4929 | 0.3579 | |
| SRP219564 | LMOD1 | 25802 | RNAseq | -0.9072 | 0.4621 | |
| TCGA | LMOD1 | 25802 | RNAseq | -0.9091 | 0.0001 |
Upregulated datasets: 1; Downregulated datasets: 9.
Survival by LMOD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LMOD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LMOD1 | 25802 | 11 | 0 | 19 | |
| GSE20123 | LMOD1 | 25802 | 11 | 0 | 19 | |
| GSE43470 | LMOD1 | 25802 | 6 | 0 | 37 | |
| GSE46452 | LMOD1 | 25802 | 3 | 1 | 55 | |
| GSE47630 | LMOD1 | 25802 | 14 | 0 | 26 | |
| GSE54993 | LMOD1 | 25802 | 0 | 6 | 64 | |
| GSE54994 | LMOD1 | 25802 | 15 | 0 | 38 | |
| GSE60625 | LMOD1 | 25802 | 0 | 0 | 11 | |
| GSE74703 | LMOD1 | 25802 | 6 | 0 | 30 | |
| GSE74704 | LMOD1 | 25802 | 5 | 0 | 15 | |
| TCGA | LMOD1 | 25802 | 43 | 5 | 48 |
Total number of gains: 114; Total number of losses: 12; Total Number of normals: 362.
Somatic mutations of LMOD1:
Generating mutation plots.
Highly correlated genes for LMOD1:
Showing top 20/1407 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LMOD1 | CNN1 | 0.907016 | 11 | 0 | 11 |
| LMOD1 | MYOCD | 0.897198 | 7 | 0 | 7 |
| LMOD1 | AFF3 | 0.880619 | 3 | 0 | 3 |
| LMOD1 | SYNM | 0.879095 | 11 | 0 | 11 |
| LMOD1 | PRUNE2 | 0.877186 | 13 | 0 | 13 |
| LMOD1 | ACTG2 | 0.873983 | 13 | 0 | 13 |
| LMOD1 | MRVI1 | 0.864937 | 8 | 0 | 8 |
| LMOD1 | MYH11 | 0.863733 | 12 | 0 | 12 |
| LMOD1 | PPP1R12B | 0.861628 | 12 | 0 | 11 |
| LMOD1 | PLN | 0.861106 | 13 | 0 | 13 |
| LMOD1 | DES | 0.858333 | 13 | 0 | 12 |
| LMOD1 | ANGPTL1 | 0.857325 | 7 | 0 | 7 |
| LMOD1 | DAAM2 | 0.851063 | 10 | 0 | 9 |
| LMOD1 | C7 | 0.842541 | 11 | 0 | 11 |
| LMOD1 | NEXN | 0.839251 | 9 | 0 | 9 |
| LMOD1 | PCP4 | 0.833428 | 11 | 0 | 11 |
| LMOD1 | ACTBL2 | 0.832894 | 3 | 0 | 3 |
| LMOD1 | LINC01082 | 0.831607 | 5 | 0 | 5 |
| LMOD1 | SORBS1 | 0.831041 | 7 | 0 | 6 |
| LMOD1 | PDZRN4 | 0.829625 | 10 | 0 | 10 |
For details and further investigation, click here
