| Full name: complement C7 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 5p13.1 | ||
| Entrez ID: 730 | HGNC ID: HGNC:1346 | Ensembl Gene: ENSG00000112936 | OMIM ID: 217070 |
| Drug and gene relationship at DGIdb | |||
Expression of C7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C7 | 730 | 202992_at | -3.6219 | 0.0559 | |
| GSE20347 | C7 | 730 | 202992_at | -1.3628 | 0.0006 | |
| GSE23400 | C7 | 730 | 202992_at | -1.1427 | 0.0000 | |
| GSE26886 | C7 | 730 | 202992_at | -0.2637 | 0.5920 | |
| GSE29001 | C7 | 730 | 202992_at | -1.0750 | 0.0110 | |
| GSE38129 | C7 | 730 | 202992_at | -2.3111 | 0.0001 | |
| GSE45670 | C7 | 730 | 202992_at | -5.3790 | 0.0000 | |
| GSE53622 | C7 | 730 | 19736 | -2.5428 | 0.0000 | |
| GSE53624 | C7 | 730 | 19736 | -1.8558 | 0.0000 | |
| GSE63941 | C7 | 730 | 202992_at | -0.0335 | 0.8542 | |
| GSE77861 | C7 | 730 | 202992_at | -0.0608 | 0.6550 | |
| GSE97050 | C7 | 730 | A_23_P213857 | -1.1035 | 0.0631 | |
| SRP064894 | C7 | 730 | RNAseq | -1.3809 | 0.0275 | |
| SRP133303 | C7 | 730 | RNAseq | -3.4016 | 0.0001 | |
| SRP159526 | C7 | 730 | RNAseq | -2.3769 | 0.0003 | |
| SRP219564 | C7 | 730 | RNAseq | -0.4113 | 0.7822 | |
| TCGA | C7 | 730 | RNAseq | -1.9239 | 0.0008 |
Upregulated datasets: 0; Downregulated datasets: 11.
Survival by C7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C7 | 730 | 9 | 0 | 21 | |
| GSE20123 | C7 | 730 | 9 | 0 | 21 | |
| GSE43470 | C7 | 730 | 17 | 0 | 26 | |
| GSE46452 | C7 | 730 | 5 | 22 | 32 | |
| GSE47630 | C7 | 730 | 6 | 12 | 22 | |
| GSE54993 | C7 | 730 | 5 | 4 | 61 | |
| GSE54994 | C7 | 730 | 24 | 2 | 27 | |
| GSE60625 | C7 | 730 | 0 | 0 | 11 | |
| GSE74703 | C7 | 730 | 13 | 0 | 23 | |
| GSE74704 | C7 | 730 | 8 | 0 | 12 | |
| TCGA | C7 | 730 | 54 | 6 | 36 |
Total number of gains: 150; Total number of losses: 46; Total Number of normals: 292.
Somatic mutations of C7:
Generating mutation plots.
Highly correlated genes for C7:
Showing top 20/1535 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C7 | ANGPTL1 | 0.88163 | 6 | 0 | 6 |
| C7 | FBXL3 | 0.865061 | 3 | 0 | 3 |
| C7 | CHRDL1 | 0.861617 | 9 | 0 | 9 |
| C7 | CLEC3B | 0.845774 | 3 | 0 | 3 |
| C7 | CYP21A2 | 0.844113 | 3 | 0 | 3 |
| C7 | LMOD1 | 0.842541 | 11 | 0 | 11 |
| C7 | CYP4V2 | 0.837938 | 3 | 0 | 3 |
| C7 | MACROD2 | 0.832761 | 3 | 0 | 3 |
| C7 | GFRA1 | 0.826637 | 6 | 0 | 6 |
| C7 | CASQ2 | 0.826223 | 11 | 0 | 11 |
| C7 | PPP1R12B | 0.813318 | 10 | 0 | 10 |
| C7 | APOD | 0.811099 | 10 | 0 | 10 |
| C7 | CNN1 | 0.809586 | 9 | 0 | 9 |
| C7 | LINC01082 | 0.799146 | 4 | 0 | 4 |
| C7 | FXYD1 | 0.795138 | 8 | 0 | 8 |
| C7 | MAOB | 0.792969 | 9 | 0 | 9 |
| C7 | OGN | 0.791356 | 11 | 0 | 10 |
| C7 | MEOX2 | 0.790881 | 8 | 0 | 7 |
| C7 | ADAMTS9-AS2 | 0.790824 | 4 | 0 | 4 |
| C7 | BOC | 0.788038 | 5 | 0 | 5 |
For details and further investigation, click here
