AGBL3

 

Full name: ATP/GTP binding protein like 3 Alias Symbol: MGC32955|CCP3
Type: protein-coding gene Cytoband: 7q33
Entrez ID: 340351 HGNC ID: HGNC:27981 Ensembl Gene: ENSG00000146856 OMIM ID: 617346
Drug and gene relationship at DGIdb

 

Expression of AGBL3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 AGBL3 340351 232395_x_at -0.1229 0.8489
GSE20347 AGBL3 340351 220649_at -0.0438 0.3279
GSE23400 AGBL3 340351 220649_at -0.0291 0.0395
GSE26886 AGBL3 340351 232395_x_at 0.3990 0.1190
GSE29001 AGBL3 340351 220649_at -0.0788 0.3392
GSE38129 AGBL3 340351 220649_at -0.0848 0.0603
GSE45670 AGBL3 340351 232395_x_at -0.6035 0.0193
GSE53622 AGBL3 340351 68775 -0.4047 0.0000
GSE53624 AGBL3 340351 68775 -0.1023 0.2378
GSE63941 AGBL3 340351 232395_x_at 0.3432 0.4315
GSE77861 AGBL3 340351 1554820_at 0.0387 0.7192
GSE97050 AGBL3 340351 A_32_P82623 -0.3765 0.3835
SRP064894 AGBL3 340351 RNAseq -0.1684 0.5679
SRP133303 AGBL3 340351 RNAseq -0.4704 0.0160
SRP159526 AGBL3 340351 RNAseq -0.1075 0.7721
SRP193095 AGBL3 340351 RNAseq -0.2877 0.0830
SRP219564 AGBL3 340351 RNAseq -0.2306 0.5220
TCGA AGBL3 340351 RNAseq -0.7602 0.0546

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by AGBL3 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of AGBL3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 AGBL3 340351 5 2 23
GSE20123 AGBL3 340351 5 2 23
GSE43470 AGBL3 340351 2 3 38
GSE46452 AGBL3 340351 7 2 50
GSE47630 AGBL3 340351 7 4 29
GSE54993 AGBL3 340351 3 5 62
GSE54994 AGBL3 340351 6 8 39
GSE60625 AGBL3 340351 0 0 11
GSE74703 AGBL3 340351 2 3 31
GSE74704 AGBL3 340351 2 2 16
TCGA AGBL3 340351 28 23 45

Total number of gains: 67; Total number of losses: 54; Total Number of normals: 367.  


 

Somatic mutations of AGBL3:

 

Generating mutation plots.

 

Highly correlated genes for AGBL3:

 

Showing top 20/184 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
AGBL3CCDC1360.734895303
AGBL3OTOGL0.68482303
AGBL3RWDD40.682078303
AGBL3KLHL230.678052403
AGBL3LONRF20.675069303
AGBL3S100B0.656151404
AGBL3STARD90.655123303
AGBL3ZBTB200.64438303
AGBL3PRKAG20.633629403
AGBL3SGCG0.630664403
AGBL3CORO2B0.629293705
AGBL3RPS160.626468403
AGBL3SNRPN0.625818303
AGBL3TRAF50.624321403
AGBL3ZNF230.624147303
AGBL3TMEM170B0.622995605
AGBL3NRXN30.619408504
AGBL3PBX10.618174403
AGBL3PRKAR2B0.617254504
AGBL3TMEM8B0.614264403

For details and further investigation, click here