| Full name: transmembrane protein 170B | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 6p24.2 | ||
| Entrez ID: 100113407 | HGNC ID: HGNC:34244 | Ensembl Gene: ENSG00000205269 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM170B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM170B | 100113407 | 235798_at | -0.3247 | 0.7514 | |
| GSE26886 | TMEM170B | 100113407 | 235798_at | 0.3310 | 0.0926 | |
| GSE45670 | TMEM170B | 100113407 | 235798_at | -1.2695 | 0.0020 | |
| GSE53622 | TMEM170B | 100113407 | 21627 | -0.7931 | 0.0000 | |
| GSE53624 | TMEM170B | 100113407 | 21627 | -0.7702 | 0.0000 | |
| GSE63941 | TMEM170B | 100113407 | 235798_at | -2.5753 | 0.0000 | |
| GSE77861 | TMEM170B | 100113407 | 235798_at | 0.0239 | 0.7907 | |
| GSE97050 | TMEM170B | 100113407 | A_32_P178966 | -0.4769 | 0.2156 | |
| SRP007169 | TMEM170B | 100113407 | RNAseq | 1.6680 | 0.0185 | |
| SRP008496 | TMEM170B | 100113407 | RNAseq | 1.1153 | 0.0153 | |
| SRP064894 | TMEM170B | 100113407 | RNAseq | 0.0834 | 0.7788 | |
| SRP133303 | TMEM170B | 100113407 | RNAseq | -0.1832 | 0.5804 | |
| SRP159526 | TMEM170B | 100113407 | RNAseq | 1.1115 | 0.0001 | |
| SRP193095 | TMEM170B | 100113407 | RNAseq | 0.2771 | 0.1884 | |
| SRP219564 | TMEM170B | 100113407 | RNAseq | 0.0296 | 0.9472 | |
| TCGA | TMEM170B | 100113407 | RNAseq | -0.6731 | 0.0004 |
Upregulated datasets: 3; Downregulated datasets: 2.
Survival by TMEM170B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM170B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM170B | 100113407 | 4 | 7 | 19 | |
| GSE20123 | TMEM170B | 100113407 | 4 | 7 | 19 | |
| GSE43470 | TMEM170B | 100113407 | 9 | 1 | 33 | |
| GSE46452 | TMEM170B | 100113407 | 1 | 10 | 48 | |
| GSE47630 | TMEM170B | 100113407 | 7 | 8 | 25 | |
| GSE54993 | TMEM170B | 100113407 | 1 | 1 | 68 | |
| GSE54994 | TMEM170B | 100113407 | 10 | 3 | 40 | |
| GSE60625 | TMEM170B | 100113407 | 0 | 1 | 10 | |
| GSE74703 | TMEM170B | 100113407 | 8 | 1 | 27 | |
| GSE74704 | TMEM170B | 100113407 | 2 | 3 | 15 | |
| TCGA | TMEM170B | 100113407 | 16 | 27 | 53 |
Total number of gains: 62; Total number of losses: 69; Total Number of normals: 357.
Somatic mutations of TMEM170B:
Generating mutation plots.
Highly correlated genes for TMEM170B:
Showing top 20/1085 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM170B | AFF3 | 0.821214 | 3 | 0 | 3 |
| TMEM170B | SLAIN1 | 0.807447 | 6 | 0 | 6 |
| TMEM170B | DIXDC1 | 0.792253 | 6 | 0 | 6 |
| TMEM170B | MBD5 | 0.785545 | 3 | 0 | 3 |
| TMEM170B | ZFAND5 | 0.784953 | 3 | 0 | 3 |
| TMEM170B | MAN1C1 | 0.770259 | 7 | 0 | 7 |
| TMEM170B | FAM8A1 | 0.76441 | 4 | 0 | 4 |
| TMEM170B | NR2F1 | 0.763347 | 3 | 0 | 3 |
| TMEM170B | FRY | 0.760804 | 6 | 0 | 6 |
| TMEM170B | FIBIN | 0.76004 | 4 | 0 | 4 |
| TMEM170B | MFAP4 | 0.751845 | 6 | 0 | 6 |
| TMEM170B | BHMT2 | 0.750934 | 6 | 0 | 6 |
| TMEM170B | PLCL1 | 0.748713 | 6 | 0 | 6 |
| TMEM170B | TAB1 | 0.747773 | 3 | 0 | 3 |
| TMEM170B | BEND5 | 0.746894 | 5 | 0 | 5 |
| TMEM170B | GYPC | 0.746392 | 6 | 0 | 6 |
| TMEM170B | FZD4 | 0.742372 | 5 | 0 | 5 |
| TMEM170B | JAM2 | 0.741136 | 6 | 0 | 6 |
| TMEM170B | CBX7 | 0.73919 | 6 | 0 | 6 |
| TMEM170B | FXYD6 | 0.738329 | 6 | 0 | 5 |
For details and further investigation, click here
