| Full name: RWD domain containing 4 | Alias Symbol: MGC10198 | ||
| Type: protein-coding gene | Cytoband: 4q35.1 | ||
| Entrez ID: 201965 | HGNC ID: HGNC:23750 | Ensembl Gene: ENSG00000182552 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of RWDD4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RWDD4 | 201965 | 225574_at | -0.1122 | 0.7908 | |
| GSE26886 | RWDD4 | 201965 | 225574_at | -0.6756 | 0.0014 | |
| GSE45670 | RWDD4 | 201965 | 225574_at | -0.0868 | 0.6887 | |
| GSE53622 | RWDD4 | 201965 | 10377 | -0.1877 | 0.0798 | |
| GSE53624 | RWDD4 | 201965 | 10377 | -0.1657 | 0.1012 | |
| GSE63941 | RWDD4 | 201965 | 225574_at | -1.3223 | 0.0071 | |
| GSE77861 | RWDD4 | 201965 | 225574_at | 0.0674 | 0.8232 | |
| GSE97050 | RWDD4 | 201965 | A_32_P76156 | -0.1454 | 0.6553 | |
| SRP007169 | RWDD4 | 201965 | RNAseq | -0.0856 | 0.8574 | |
| SRP008496 | RWDD4 | 201965 | RNAseq | 0.0115 | 0.9644 | |
| SRP064894 | RWDD4 | 201965 | RNAseq | -0.0553 | 0.7365 | |
| SRP133303 | RWDD4 | 201965 | RNAseq | 0.6107 | 0.0034 | |
| SRP159526 | RWDD4 | 201965 | RNAseq | -0.1363 | 0.3923 | |
| SRP193095 | RWDD4 | 201965 | RNAseq | -0.1294 | 0.3321 | |
| SRP219564 | RWDD4 | 201965 | RNAseq | -0.2317 | 0.2806 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by RWDD4 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of RWDD4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RWDD4 | 201965 | 2 | 11 | 17 | |
| GSE20123 | RWDD4 | 201965 | 2 | 11 | 17 | |
| GSE43470 | RWDD4 | 201965 | 1 | 12 | 30 | |
| GSE46452 | RWDD4 | 201965 | 1 | 36 | 22 | |
| GSE47630 | RWDD4 | 201965 | 0 | 22 | 18 | |
| GSE54993 | RWDD4 | 201965 | 10 | 0 | 60 | |
| GSE54994 | RWDD4 | 201965 | 2 | 12 | 39 | |
| GSE60625 | RWDD4 | 201965 | 0 | 0 | 11 | |
| GSE74703 | RWDD4 | 201965 | 1 | 9 | 26 | |
| GSE74704 | RWDD4 | 201965 | 1 | 5 | 14 | |
| TCGA | RWDD4 | 201965 | 11 | 32 | 53 |
Total number of gains: 31; Total number of losses: 150; Total Number of normals: 307.
Somatic mutations of RWDD4:
Generating mutation plots.
Highly correlated genes for RWDD4:
Showing top 20/472 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RWDD4 | PIGA | 0.81184 | 3 | 0 | 3 |
| RWDD4 | LCOR | 0.781536 | 3 | 0 | 3 |
| RWDD4 | PPID | 0.766532 | 3 | 0 | 3 |
| RWDD4 | COIL | 0.764276 | 3 | 0 | 3 |
| RWDD4 | CHUK | 0.747457 | 3 | 0 | 3 |
| RWDD4 | PRDX3 | 0.736075 | 3 | 0 | 3 |
| RWDD4 | RSL24D1 | 0.735597 | 3 | 0 | 3 |
| RWDD4 | POLI | 0.733569 | 4 | 0 | 3 |
| RWDD4 | DCTD | 0.732105 | 6 | 0 | 5 |
| RWDD4 | FBXO3 | 0.731745 | 3 | 0 | 3 |
| RWDD4 | PUS7L | 0.731298 | 3 | 0 | 3 |
| RWDD4 | NCKAP1 | 0.726295 | 3 | 0 | 3 |
| RWDD4 | KPNA3 | 0.726203 | 4 | 0 | 4 |
| RWDD4 | ZNF227 | 0.724306 | 4 | 0 | 4 |
| RWDD4 | IFT74 | 0.721175 | 4 | 0 | 4 |
| RWDD4 | SUMO3 | 0.719849 | 3 | 0 | 3 |
| RWDD4 | NAA20 | 0.719545 | 3 | 0 | 3 |
| RWDD4 | AIDA | 0.715681 | 3 | 0 | 3 |
| RWDD4 | IBTK | 0.713563 | 3 | 0 | 3 |
| RWDD4 | TMEM218 | 0.710211 | 4 | 0 | 3 |
For details and further investigation, click here
