| Full name: neurexin 3 | Alias Symbol: KIAA0743 | ||
| Type: protein-coding gene | Cytoband: 14q24.3-q31.1 | ||
| Entrez ID: 9369 | HGNC ID: HGNC:8010 | Ensembl Gene: ENSG00000021645 | OMIM ID: 600567 |
| Drug and gene relationship at DGIdb | |||
Expression of NRXN3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NRXN3 | 9369 | 229649_at | -1.5063 | 0.4098 | |
| GSE20347 | NRXN3 | 9369 | 215021_s_at | 0.0355 | 0.7248 | |
| GSE23400 | NRXN3 | 9369 | 215020_at | -0.2447 | 0.0093 | |
| GSE26886 | NRXN3 | 9369 | 215021_s_at | 0.2178 | 0.2434 | |
| GSE29001 | NRXN3 | 9369 | 205795_at | -0.1542 | 0.7962 | |
| GSE38129 | NRXN3 | 9369 | 205795_at | -0.6173 | 0.3232 | |
| GSE45670 | NRXN3 | 9369 | 229649_at | -1.8450 | 0.0011 | |
| GSE53622 | NRXN3 | 9369 | 37804 | -0.7066 | 0.0018 | |
| GSE53624 | NRXN3 | 9369 | 37804 | -0.1460 | 0.2795 | |
| GSE63941 | NRXN3 | 9369 | 229649_at | -0.0514 | 0.9790 | |
| GSE77861 | NRXN3 | 9369 | 215020_at | 0.0371 | 0.7907 | |
| GSE97050 | NRXN3 | 9369 | A_33_P3851023 | -1.3284 | 0.1972 | |
| SRP064894 | NRXN3 | 9369 | RNAseq | 1.0194 | 0.0312 | |
| SRP133303 | NRXN3 | 9369 | RNAseq | 0.7330 | 0.2568 | |
| SRP159526 | NRXN3 | 9369 | RNAseq | 0.2057 | 0.7234 | |
| SRP193095 | NRXN3 | 9369 | RNAseq | 0.8912 | 0.0008 | |
| SRP219564 | NRXN3 | 9369 | RNAseq | -0.5641 | 0.6504 | |
| TCGA | NRXN3 | 9369 | RNAseq | -0.4955 | 0.0752 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by NRXN3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NRXN3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NRXN3 | 9369 | 7 | 3 | 20 | |
| GSE20123 | NRXN3 | 9369 | 7 | 3 | 20 | |
| GSE43470 | NRXN3 | 9369 | 8 | 3 | 32 | |
| GSE46452 | NRXN3 | 9369 | 16 | 3 | 40 | |
| GSE47630 | NRXN3 | 9369 | 11 | 8 | 21 | |
| GSE54993 | NRXN3 | 9369 | 3 | 8 | 59 | |
| GSE54994 | NRXN3 | 9369 | 19 | 4 | 30 | |
| GSE60625 | NRXN3 | 9369 | 0 | 2 | 9 | |
| GSE74703 | NRXN3 | 9369 | 7 | 3 | 26 | |
| GSE74704 | NRXN3 | 9369 | 3 | 3 | 14 | |
| TCGA | NRXN3 | 9369 | 31 | 18 | 47 |
Total number of gains: 112; Total number of losses: 58; Total Number of normals: 318.
Somatic mutations of NRXN3:
Generating mutation plots.
Highly correlated genes for NRXN3:
Showing top 20/844 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NRXN3 | SLC35F1 | 0.789144 | 3 | 0 | 3 |
| NRXN3 | NEGR1 | 0.786898 | 4 | 0 | 4 |
| NRXN3 | HSPB7 | 0.756539 | 8 | 0 | 7 |
| NRXN3 | CACNA1C | 0.7494 | 5 | 0 | 5 |
| NRXN3 | PPP1R14A | 0.746924 | 6 | 0 | 5 |
| NRXN3 | RBM24 | 0.741204 | 5 | 0 | 5 |
| NRXN3 | ADARB1 | 0.737339 | 6 | 0 | 5 |
| NRXN3 | ILDR2 | 0.737121 | 3 | 0 | 3 |
| NRXN3 | ENOX1 | 0.73588 | 5 | 0 | 5 |
| NRXN3 | MTUS2 | 0.735681 | 4 | 0 | 4 |
| NRXN3 | ANGPT1 | 0.732504 | 7 | 0 | 7 |
| NRXN3 | ZBTB47 | 0.732035 | 3 | 0 | 3 |
| NRXN3 | CYS1 | 0.732015 | 4 | 0 | 4 |
| NRXN3 | SH3BGR | 0.731922 | 7 | 0 | 6 |
| NRXN3 | RUNX1T1 | 0.730529 | 5 | 0 | 4 |
| NRXN3 | TMEM8B | 0.729883 | 5 | 0 | 5 |
| NRXN3 | MTURN | 0.729055 | 3 | 0 | 3 |
| NRXN3 | RASD2 | 0.722977 | 3 | 0 | 3 |
| NRXN3 | ITGA1 | 0.722859 | 6 | 0 | 5 |
| NRXN3 | DPT | 0.722297 | 6 | 0 | 5 |
For details and further investigation, click here
