| Full name: cytochrome c oxidase assembly factor COX16 | Alias Symbol: HSPC203 | ||
| Type: protein-coding gene | Cytoband: 14q24.2 | ||
| Entrez ID: 51241 | HGNC ID: HGNC:20213 | Ensembl Gene: ENSG00000133983 | OMIM ID: 618064 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of COX16:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COX16 | 51241 | 223191_at | 0.1656 | 0.7481 | |
| GSE26886 | COX16 | 51241 | 223191_at | -0.1496 | 0.4237 | |
| GSE45670 | COX16 | 51241 | 223191_at | 0.3045 | 0.0050 | |
| GSE63941 | COX16 | 51241 | 223191_at | 0.3630 | 0.2932 | |
| GSE77861 | COX16 | 51241 | 223191_at | -0.1254 | 0.6899 | |
| GSE97050 | COX16 | 51241 | A_23_P53957 | 0.1518 | 0.6416 | |
| SRP007169 | COX16 | 51241 | RNAseq | -0.5312 | 0.0826 | |
| SRP008496 | COX16 | 51241 | RNAseq | -0.5365 | 0.0041 | |
| SRP064894 | COX16 | 51241 | RNAseq | 0.1329 | 0.5619 | |
| SRP133303 | COX16 | 51241 | RNAseq | 0.1780 | 0.2489 | |
| SRP159526 | COX16 | 51241 | RNAseq | -0.1172 | 0.6176 | |
| SRP193095 | COX16 | 51241 | RNAseq | -0.5752 | 0.0002 | |
| SRP219564 | COX16 | 51241 | RNAseq | 0.1124 | 0.7876 | |
| TCGA | COX16 | 51241 | RNAseq | -0.0958 | 0.0790 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by COX16 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of COX16:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COX16 | 51241 | 8 | 3 | 19 | |
| GSE20123 | COX16 | 51241 | 8 | 3 | 19 | |
| GSE43470 | COX16 | 51241 | 8 | 3 | 32 | |
| GSE46452 | COX16 | 51241 | 16 | 3 | 40 | |
| GSE47630 | COX16 | 51241 | 11 | 9 | 20 | |
| GSE54993 | COX16 | 51241 | 3 | 9 | 58 | |
| GSE54994 | COX16 | 51241 | 18 | 5 | 30 | |
| GSE60625 | COX16 | 51241 | 0 | 2 | 9 | |
| GSE74703 | COX16 | 51241 | 7 | 3 | 26 | |
| GSE74704 | COX16 | 51241 | 3 | 3 | 14 | |
| TCGA | COX16 | 51241 | 32 | 16 | 48 |
Total number of gains: 114; Total number of losses: 59; Total Number of normals: 315.
Somatic mutations of COX16:
Generating mutation plots.
Highly correlated genes for COX16:
Showing top 20/203 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COX16 | C8orf76 | 0.825144 | 3 | 0 | 3 |
| COX16 | GLRX3 | 0.772061 | 3 | 0 | 3 |
| COX16 | IPO4 | 0.760077 | 3 | 0 | 3 |
| COX16 | SLIRP | 0.75242 | 5 | 0 | 5 |
| COX16 | AGMAT | 0.752014 | 3 | 0 | 3 |
| COX16 | FDPS | 0.751985 | 4 | 0 | 4 |
| COX16 | NEK4 | 0.750613 | 3 | 0 | 3 |
| COX16 | SLC39A9 | 0.739055 | 5 | 0 | 5 |
| COX16 | XXYLT1 | 0.729251 | 3 | 0 | 3 |
| COX16 | COCH | 0.725052 | 3 | 0 | 3 |
| COX16 | MRPL36 | 0.723877 | 3 | 0 | 3 |
| COX16 | NSUN3 | 0.721749 | 3 | 0 | 3 |
| COX16 | BTF3L4 | 0.721128 | 4 | 0 | 3 |
| COX16 | DDX55 | 0.719945 | 3 | 0 | 3 |
| COX16 | RPL36AL | 0.7192 | 5 | 0 | 4 |
| COX16 | TMEM167A | 0.718221 | 4 | 0 | 4 |
| COX16 | ATG2B | 0.718123 | 3 | 0 | 3 |
| COX16 | NIT2 | 0.715832 | 3 | 0 | 3 |
| COX16 | TMED10 | 0.715339 | 4 | 0 | 3 |
| COX16 | RBM17 | 0.715007 | 3 | 0 | 3 |
For details and further investigation, click here
