| Full name: Abelson helper integration site 1 | Alias Symbol: FLJ20069|ORF1|JBTS3 | ||
| Type: protein-coding gene | Cytoband: 6q23.3 | ||
| Entrez ID: 54806 | HGNC ID: HGNC:21575 | Ensembl Gene: ENSG00000135541 | OMIM ID: 608894 |
| Drug and gene relationship at DGIdb | |||
Expression of AHI1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AHI1 | 54806 | 221569_at | -0.0458 | 0.9518 | |
| GSE20347 | AHI1 | 54806 | 221569_at | 0.4152 | 0.0397 | |
| GSE23400 | AHI1 | 54806 | 221569_at | -0.0321 | 0.7104 | |
| GSE26886 | AHI1 | 54806 | 221569_at | 0.9119 | 0.0001 | |
| GSE29001 | AHI1 | 54806 | 221569_at | 0.0937 | 0.7804 | |
| GSE38129 | AHI1 | 54806 | 221569_at | 0.0589 | 0.8021 | |
| GSE45670 | AHI1 | 54806 | 221569_at | -0.4845 | 0.0454 | |
| GSE53622 | AHI1 | 54806 | 2309 | 0.1503 | 0.1598 | |
| GSE53624 | AHI1 | 54806 | 2309 | 0.0992 | 0.1948 | |
| GSE63941 | AHI1 | 54806 | 221569_at | -2.3916 | 0.0006 | |
| GSE77861 | AHI1 | 54806 | 221569_at | 0.2937 | 0.2902 | |
| GSE97050 | AHI1 | 54806 | A_23_P70746 | 0.0430 | 0.8678 | |
| SRP007169 | AHI1 | 54806 | RNAseq | 0.4535 | 0.3531 | |
| SRP008496 | AHI1 | 54806 | RNAseq | 0.7271 | 0.0220 | |
| SRP064894 | AHI1 | 54806 | RNAseq | 0.1944 | 0.4056 | |
| SRP133303 | AHI1 | 54806 | RNAseq | -0.0511 | 0.7431 | |
| SRP159526 | AHI1 | 54806 | RNAseq | 0.0568 | 0.8594 | |
| SRP193095 | AHI1 | 54806 | RNAseq | 0.0860 | 0.6294 | |
| SRP219564 | AHI1 | 54806 | RNAseq | 0.2031 | 0.5721 | |
| TCGA | AHI1 | 54806 | RNAseq | -0.3099 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by AHI1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AHI1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AHI1 | 54806 | 5 | 4 | 21 | |
| GSE20123 | AHI1 | 54806 | 5 | 3 | 22 | |
| GSE43470 | AHI1 | 54806 | 5 | 0 | 38 | |
| GSE46452 | AHI1 | 54806 | 3 | 10 | 46 | |
| GSE47630 | AHI1 | 54806 | 10 | 4 | 26 | |
| GSE54993 | AHI1 | 54806 | 3 | 2 | 65 | |
| GSE54994 | AHI1 | 54806 | 9 | 7 | 37 | |
| GSE60625 | AHI1 | 54806 | 0 | 1 | 10 | |
| GSE74703 | AHI1 | 54806 | 4 | 0 | 32 | |
| GSE74704 | AHI1 | 54806 | 2 | 1 | 17 | |
| TCGA | AHI1 | 54806 | 14 | 17 | 65 |
Total number of gains: 60; Total number of losses: 49; Total Number of normals: 379.
Somatic mutations of AHI1:
Generating mutation plots.
Highly correlated genes for AHI1:
Showing top 20/374 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AHI1 | ZNF660 | 0.744837 | 3 | 0 | 3 |
| AHI1 | TMEM71 | 0.737667 | 3 | 0 | 3 |
| AHI1 | ZNF605 | 0.73031 | 3 | 0 | 3 |
| AHI1 | TNFSF13B | 0.675152 | 3 | 0 | 3 |
| AHI1 | NUMBL | 0.671582 | 4 | 0 | 4 |
| AHI1 | SLC25A33 | 0.651462 | 4 | 0 | 3 |
| AHI1 | GPRASP1 | 0.643755 | 7 | 0 | 6 |
| AHI1 | CEP57L1 | 0.641156 | 4 | 0 | 4 |
| AHI1 | TMEM140 | 0.63626 | 5 | 0 | 4 |
| AHI1 | SERPING1 | 0.635879 | 6 | 0 | 5 |
| AHI1 | BMP5 | 0.63509 | 3 | 0 | 3 |
| AHI1 | EGR2 | 0.626942 | 3 | 0 | 3 |
| AHI1 | SCD5 | 0.619687 | 3 | 0 | 3 |
| AHI1 | NOL9 | 0.618568 | 4 | 0 | 3 |
| AHI1 | ANK2 | 0.618454 | 6 | 0 | 5 |
| AHI1 | PTPDC1 | 0.618404 | 5 | 0 | 3 |
| AHI1 | CDH11 | 0.61562 | 3 | 0 | 3 |
| AHI1 | EXT1 | 0.615481 | 3 | 0 | 3 |
| AHI1 | SAT2 | 0.615336 | 4 | 0 | 3 |
| AHI1 | ZDHHC17 | 0.613723 | 11 | 0 | 9 |
For details and further investigation, click here
