| Full name: centrosomal protein 57 like 1 | Alias Symbol: bA487F23.2|MGC21731 | ||
| Type: protein-coding gene | Cytoband: 6q21 | ||
| Entrez ID: 285753 | HGNC ID: HGNC:21561 | Ensembl Gene: ENSG00000183137 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CEP57L1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CEP57L1 | 285753 | 243118_at | -0.1968 | 0.5975 | |
| GSE26886 | CEP57L1 | 285753 | 243118_at | 0.5241 | 0.0158 | |
| GSE45670 | CEP57L1 | 285753 | 1554019_s_at | 0.3740 | 0.0165 | |
| GSE53622 | CEP57L1 | 285753 | 144788 | 0.5349 | 0.0000 | |
| GSE53624 | CEP57L1 | 285753 | 144788 | 0.6423 | 0.0000 | |
| GSE63941 | CEP57L1 | 285753 | 243118_at | -0.8938 | 0.0048 | |
| GSE77861 | CEP57L1 | 285753 | 1560418_at | -0.0738 | 0.5666 | |
| GSE97050 | CEP57L1 | 285753 | A_23_P59358 | 0.0955 | 0.7673 | |
| SRP007169 | CEP57L1 | 285753 | RNAseq | 0.3132 | 0.5542 | |
| SRP008496 | CEP57L1 | 285753 | RNAseq | 0.0978 | 0.7663 | |
| SRP064894 | CEP57L1 | 285753 | RNAseq | 0.4265 | 0.0165 | |
| SRP133303 | CEP57L1 | 285753 | RNAseq | 0.2653 | 0.0298 | |
| SRP159526 | CEP57L1 | 285753 | RNAseq | 0.2165 | 0.3704 | |
| SRP193095 | CEP57L1 | 285753 | RNAseq | 0.1769 | 0.0310 | |
| SRP219564 | CEP57L1 | 285753 | RNAseq | 0.2158 | 0.6666 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CEP57L1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of CEP57L1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CEP57L1 | 285753 | 3 | 3 | 24 | |
| GSE20123 | CEP57L1 | 285753 | 3 | 2 | 25 | |
| GSE43470 | CEP57L1 | 285753 | 3 | 1 | 39 | |
| GSE46452 | CEP57L1 | 285753 | 2 | 11 | 46 | |
| GSE47630 | CEP57L1 | 285753 | 9 | 4 | 27 | |
| GSE54993 | CEP57L1 | 285753 | 3 | 2 | 65 | |
| GSE54994 | CEP57L1 | 285753 | 8 | 8 | 37 | |
| GSE60625 | CEP57L1 | 285753 | 0 | 2 | 9 | |
| GSE74703 | CEP57L1 | 285753 | 2 | 1 | 33 | |
| GSE74704 | CEP57L1 | 285753 | 1 | 0 | 19 | |
| TCGA | CEP57L1 | 285753 | 6 | 24 | 66 |
Total number of gains: 40; Total number of losses: 58; Total Number of normals: 390.
Somatic mutations of CEP57L1:
Generating mutation plots.
Highly correlated genes for CEP57L1:
Showing top 20/262 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CEP57L1 | AAMDC | 0.718809 | 3 | 0 | 3 |
| CEP57L1 | PGR | 0.688502 | 3 | 0 | 3 |
| CEP57L1 | SYNC | 0.676466 | 3 | 0 | 3 |
| CEP57L1 | SH3GL2 | 0.675308 | 4 | 0 | 3 |
| CEP57L1 | HECTD2 | 0.660855 | 3 | 0 | 3 |
| CEP57L1 | ORC3 | 0.641547 | 5 | 0 | 5 |
| CEP57L1 | AHI1 | 0.641156 | 4 | 0 | 4 |
| CEP57L1 | PTGER2 | 0.639713 | 3 | 0 | 3 |
| CEP57L1 | SPATA7 | 0.639443 | 4 | 0 | 3 |
| CEP57L1 | CYP20A1 | 0.639052 | 3 | 0 | 3 |
| CEP57L1 | SERINC1 | 0.639023 | 3 | 0 | 3 |
| CEP57L1 | FGF14-AS2 | 0.636151 | 3 | 0 | 3 |
| CEP57L1 | HAUS7 | 0.635793 | 3 | 0 | 3 |
| CEP57L1 | TBP | 0.63426 | 4 | 0 | 4 |
| CEP57L1 | AGTR1 | 0.632644 | 3 | 0 | 3 |
| CEP57L1 | PLEKHG2 | 0.630314 | 3 | 0 | 3 |
| CEP57L1 | VKORC1 | 0.627914 | 4 | 0 | 3 |
| CEP57L1 | RAB34 | 0.624635 | 3 | 0 | 3 |
| CEP57L1 | LPL | 0.622631 | 5 | 0 | 4 |
| CEP57L1 | TBX15 | 0.618005 | 5 | 0 | 5 |
For details and further investigation, click here
