| Full name: TNF superfamily member 13b | Alias Symbol: BAFF|THANK|BLYS|TALL-1|TALL1|CD257 | ||
| Type: protein-coding gene | Cytoband: 13q33.3 | ||
| Entrez ID: 10673 | HGNC ID: HGNC:11929 | Ensembl Gene: ENSG00000102524 | OMIM ID: 603969 |
| Drug and gene relationship at DGIdb | |||
TNFSF13B involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04064 | NF-kappa B signaling pathway |
Expression of TNFSF13B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TNFSF13B | 10673 | 223502_s_at | 0.3108 | 0.8569 | |
| GSE26886 | TNFSF13B | 10673 | 223502_s_at | 0.8703 | 0.1037 | |
| GSE45670 | TNFSF13B | 10673 | 223502_s_at | -0.5087 | 0.2891 | |
| GSE53622 | TNFSF13B | 10673 | 66193 | 0.0047 | 0.9711 | |
| GSE53624 | TNFSF13B | 10673 | 66193 | -0.0685 | 0.4478 | |
| GSE63941 | TNFSF13B | 10673 | 223502_s_at | -4.4792 | 0.0000 | |
| GSE77861 | TNFSF13B | 10673 | 223502_s_at | 0.2865 | 0.1503 | |
| GSE97050 | TNFSF13B | 10673 | A_23_P14174 | 0.5044 | 0.3997 | |
| SRP007169 | TNFSF13B | 10673 | RNAseq | 2.1171 | 0.0043 | |
| SRP064894 | TNFSF13B | 10673 | RNAseq | 0.8619 | 0.0112 | |
| SRP133303 | TNFSF13B | 10673 | RNAseq | 0.1579 | 0.5987 | |
| SRP159526 | TNFSF13B | 10673 | RNAseq | 0.3971 | 0.5448 | |
| SRP193095 | TNFSF13B | 10673 | RNAseq | 0.7042 | 0.0042 | |
| SRP219564 | TNFSF13B | 10673 | RNAseq | 1.2493 | 0.0199 | |
| TCGA | TNFSF13B | 10673 | RNAseq | 0.3915 | 0.0882 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by TNFSF13B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TNFSF13B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TNFSF13B | 10673 | 6 | 11 | 13 | |
| GSE20123 | TNFSF13B | 10673 | 6 | 10 | 14 | |
| GSE43470 | TNFSF13B | 10673 | 4 | 12 | 27 | |
| GSE46452 | TNFSF13B | 10673 | 1 | 31 | 27 | |
| GSE47630 | TNFSF13B | 10673 | 3 | 26 | 11 | |
| GSE54993 | TNFSF13B | 10673 | 11 | 4 | 55 | |
| GSE54994 | TNFSF13B | 10673 | 8 | 8 | 37 | |
| GSE60625 | TNFSF13B | 10673 | 0 | 3 | 8 | |
| GSE74703 | TNFSF13B | 10673 | 3 | 9 | 24 | |
| GSE74704 | TNFSF13B | 10673 | 4 | 10 | 6 | |
| TCGA | TNFSF13B | 10673 | 19 | 33 | 44 |
Total number of gains: 65; Total number of losses: 157; Total Number of normals: 266.
Somatic mutations of TNFSF13B:
Generating mutation plots.
Highly correlated genes for TNFSF13B:
Showing top 20/260 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TNFSF13B | SLA2 | 0.793861 | 3 | 0 | 3 |
| TNFSF13B | APBB1IP | 0.761677 | 6 | 0 | 6 |
| TNFSF13B | P4HA3 | 0.758837 | 3 | 0 | 3 |
| TNFSF13B | TPST1 | 0.71982 | 3 | 0 | 3 |
| TNFSF13B | RNASE6 | 0.713777 | 5 | 0 | 5 |
| TNFSF13B | DOCK2 | 0.712055 | 8 | 0 | 8 |
| TNFSF13B | RASSF1 | 0.71107 | 3 | 0 | 3 |
| TNFSF13B | TMEM200A | 0.710071 | 4 | 0 | 4 |
| TNFSF13B | C1QB | 0.703776 | 7 | 0 | 6 |
| TNFSF13B | EVI2A | 0.70259 | 6 | 0 | 5 |
| TNFSF13B | FMNL1 | 0.701986 | 4 | 0 | 4 |
| TNFSF13B | CD48 | 0.699395 | 6 | 0 | 6 |
| TNFSF13B | TNFRSF1B | 0.698689 | 7 | 0 | 7 |
| TNFSF13B | SFMBT2 | 0.694808 | 4 | 0 | 3 |
| TNFSF13B | IGFLR1 | 0.694649 | 6 | 0 | 5 |
| TNFSF13B | C1QA | 0.694144 | 7 | 0 | 7 |
| TNFSF13B | AKNA | 0.693389 | 6 | 0 | 5 |
| TNFSF13B | FCGR2A | 0.691686 | 6 | 0 | 6 |
| TNFSF13B | ITGB2 | 0.689408 | 6 | 0 | 6 |
| TNFSF13B | CXCL6 | 0.681671 | 3 | 0 | 3 |
For details and further investigation, click here
