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Multi-Omics Database of ESCC

 

TNFSF13B

 

Full name: TNF superfamily member 13b Alias Symbol: BAFF|THANK|BLYS|TALL-1|TALL1|CD257
Type: protein-coding gene Cytoband: 13q33.3
Entrez ID: 10673 HGNC ID: HGNC:11929 Ensembl Gene: ENSG00000102524 OMIM ID: 603969
Drug and gene relationship at DGIdb

 

TNFSF13B involved pathways:

KEGG pathway Description View
hsa04064NF-kappa B signaling pathway

 

Expression of TNFSF13B:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TNFSF13B 10673 223502_s_at 0.3108 0.8569
GSE26886 TNFSF13B 10673 223502_s_at 0.8703 0.1037
GSE45670 TNFSF13B 10673 223502_s_at -0.5087 0.2891
GSE53622 TNFSF13B 10673 66193 0.0047 0.9711
GSE53624 TNFSF13B 10673 66193 -0.0685 0.4478
GSE63941 TNFSF13B 10673 223502_s_at -4.4792 0.0000
GSE77861 TNFSF13B 10673 223502_s_at 0.2865 0.1503
GSE97050 TNFSF13B 10673 A_23_P14174 0.5044 0.3997
SRP007169 TNFSF13B 10673 RNAseq 2.1171 0.0043
SRP064894 TNFSF13B 10673 RNAseq 0.8619 0.0112
SRP133303 TNFSF13B 10673 RNAseq 0.1579 0.5987
SRP159526 TNFSF13B 10673 RNAseq 0.3971 0.5448
SRP193095 TNFSF13B 10673 RNAseq 0.7042 0.0042
SRP219564 TNFSF13B 10673 RNAseq 1.2493 0.0199
TCGA TNFSF13B 10673 RNAseq 0.3915 0.0882

Upregulated datasets: 2; Downregulated datasets: 1.  

 

Survival by TNFSF13B expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of TNFSF13B:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TNFSF13B 10673 6 11 13
GSE20123 TNFSF13B 10673 6 10 14
GSE43470 TNFSF13B 10673 4 12 27
GSE46452 TNFSF13B 10673 1 31 27
GSE47630 TNFSF13B 10673 3 26 11
GSE54993 TNFSF13B 10673 11 4 55
GSE54994 TNFSF13B 10673 8 8 37
GSE60625 TNFSF13B 10673 0 3 8
GSE74703 TNFSF13B 10673 3 9 24
GSE74704 TNFSF13B 10673 4 10 6
TCGA TNFSF13B 10673 19 33 44

Total number of gains: 65; Total number of losses: 157; Total Number of normals: 266.  

 

Somatic mutations of TNFSF13B:

 

Generating mutation plots.

 

Highly correlated genes for TNFSF13B:

 

Showing top 20/260 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TNFSF13BSLA20.793861303
TNFSF13BAPBB1IP0.761677606
TNFSF13BP4HA30.758837303
TNFSF13BTPST10.71982303
TNFSF13BRNASE60.713777505
TNFSF13BDOCK20.712055808
TNFSF13BRASSF10.71107303
TNFSF13BTMEM200A0.710071404
TNFSF13BC1QB0.703776706
TNFSF13BEVI2A0.70259605
TNFSF13BFMNL10.701986404
TNFSF13BCD480.699395606
TNFSF13BTNFRSF1B0.698689707
TNFSF13BSFMBT20.694808403
TNFSF13BIGFLR10.694649605
TNFSF13BC1QA0.694144707
TNFSF13BAKNA0.693389605
TNFSF13BFCGR2A0.691686606
TNFSF13BITGB20.689408606
TNFSF13BCXCL60.681671303

For details and further investigation, click here