CDH11

 

Full name: cadherin 11 Alias Symbol: OB|CAD11
Type: protein-coding gene Cytoband: 16q21
Entrez ID: 1009 HGNC ID: HGNC:1750 Ensembl Gene: ENSG00000140937 OMIM ID: 600023
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of CDH11:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CDH11 1009 207173_x_at 1.0607 0.1742
GSE20347 CDH11 1009 207173_x_at 2.7231 0.0000
GSE23400 CDH11 1009 207173_x_at 2.5749 0.0000
GSE26886 CDH11 1009 207173_x_at 3.3278 0.0000
GSE29001 CDH11 1009 207173_x_at 1.8373 0.0009
GSE38129 CDH11 1009 207173_x_at 2.7332 0.0000
GSE45670 CDH11 1009 207173_x_at 0.6388 0.4779
GSE53622 CDH11 1009 10358 2.4815 0.0000
GSE53624 CDH11 1009 10358 2.5987 0.0000
GSE63941 CDH11 1009 207172_s_at -4.0796 0.0000
GSE77861 CDH11 1009 207172_s_at 0.7822 0.0386
GSE97050 CDH11 1009 A_23_P152305 1.2574 0.1057
SRP007169 CDH11 1009 RNAseq 4.7277 0.0000
SRP008496 CDH11 1009 RNAseq 5.7692 0.0000
SRP064894 CDH11 1009 RNAseq 2.7578 0.0000
SRP133303 CDH11 1009 RNAseq 2.4511 0.0000
SRP159526 CDH11 1009 RNAseq 2.9166 0.0000
SRP193095 CDH11 1009 RNAseq 3.1141 0.0000
SRP219564 CDH11 1009 RNAseq 2.0381 0.0032
TCGA CDH11 1009 RNAseq 0.3338 0.0181

Upregulated datasets: 14; Downregulated datasets: 1.  

 

Survival by CDH11 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of CDH11:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CDH11 1009 5 0 25
GSE20123 CDH11 1009 5 0 25
GSE43470 CDH11 1009 2 9 32
GSE46452 CDH11 1009 38 1 20
GSE47630 CDH11 1009 10 8 22
GSE54993 CDH11 1009 2 4 64
GSE54994 CDH11 1009 7 10 36
GSE60625 CDH11 1009 4 0 7
GSE74703 CDH11 1009 2 6 28
GSE74704 CDH11 1009 4 0 16
TCGA CDH11 1009 28 11 57

Total number of gains: 107; Total number of losses: 49; Total Number of normals: 332.  

 

Somatic mutations of CDH11:

 

Generating mutation plots.

 

Highly correlated genes for CDH11:

 

Showing top 20/1469 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CDH11VCAN0.88201513013
CDH11COL6A30.84415213013
CDH11SULF10.8294113013
CDH11COL5A20.82839313013
CDH11COL3A10.82037913013
CDH11POSTN0.81343113012
CDH11SPARC0.81013113013
CDH11COL5A10.80750213012
CDH11COL1A20.80597913012
CDH11CTHRC10.800899909
CDH11THY10.79771913013
CDH11FAP0.79721311011
CDH11FNDC10.796521808
CDH11CTSK0.79598613012
CDH11LOXL20.79567812012
CDH11TRAM20.79348813013
CDH11MFAP20.78774912011
CDH11PXDN0.78667713012
CDH11FCGR3A0.783325303
CDH11PYCR20.782514303

For details and further investigation, click here