| Full name: A-kinase anchoring protein 10 | Alias Symbol: D-AKAP2|PRKA10|MGC9414 | ||
| Type: protein-coding gene | Cytoband: 17p11.2 | ||
| Entrez ID: 11216 | HGNC ID: HGNC:368 | Ensembl Gene: ENSG00000108599 | OMIM ID: 604694 |
| Drug and gene relationship at DGIdb | |||
Expression of AKAP10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AKAP10 | 11216 | 213396_s_at | -0.0813 | 0.7408 | |
| GSE20347 | AKAP10 | 11216 | 213396_s_at | -0.0784 | 0.7838 | |
| GSE23400 | AKAP10 | 11216 | 213396_s_at | 0.1072 | 0.1211 | |
| GSE26886 | AKAP10 | 11216 | 213396_s_at | -0.0321 | 0.8543 | |
| GSE29001 | AKAP10 | 11216 | 213396_s_at | 0.1591 | 0.6403 | |
| GSE38129 | AKAP10 | 11216 | 213396_s_at | -0.0672 | 0.7153 | |
| GSE45670 | AKAP10 | 11216 | 236007_at | 0.2450 | 0.1916 | |
| GSE53622 | AKAP10 | 11216 | 25700 | 0.1727 | 0.0063 | |
| GSE53624 | AKAP10 | 11216 | 25177 | -0.0109 | 0.8615 | |
| GSE63941 | AKAP10 | 11216 | 236007_at | 0.8560 | 0.2757 | |
| GSE77861 | AKAP10 | 11216 | 213396_s_at | 0.3433 | 0.3532 | |
| GSE97050 | AKAP10 | 11216 | A_23_P317105 | 0.2083 | 0.3485 | |
| SRP007169 | AKAP10 | 11216 | RNAseq | 0.1750 | 0.5719 | |
| SRP008496 | AKAP10 | 11216 | RNAseq | 0.0433 | 0.8199 | |
| SRP064894 | AKAP10 | 11216 | RNAseq | 0.3653 | 0.1425 | |
| SRP133303 | AKAP10 | 11216 | RNAseq | 0.2294 | 0.0372 | |
| SRP159526 | AKAP10 | 11216 | RNAseq | -0.0453 | 0.8381 | |
| SRP193095 | AKAP10 | 11216 | RNAseq | 0.0488 | 0.4801 | |
| SRP219564 | AKAP10 | 11216 | RNAseq | -0.0341 | 0.8863 | |
| TCGA | AKAP10 | 11216 | RNAseq | -0.1575 | 0.0027 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by AKAP10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AKAP10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AKAP10 | 11216 | 3 | 3 | 24 | |
| GSE20123 | AKAP10 | 11216 | 3 | 4 | 23 | |
| GSE43470 | AKAP10 | 11216 | 1 | 5 | 37 | |
| GSE46452 | AKAP10 | 11216 | 34 | 1 | 24 | |
| GSE47630 | AKAP10 | 11216 | 7 | 1 | 32 | |
| GSE54993 | AKAP10 | 11216 | 3 | 3 | 64 | |
| GSE54994 | AKAP10 | 11216 | 6 | 6 | 41 | |
| GSE60625 | AKAP10 | 11216 | 4 | 0 | 7 | |
| GSE74703 | AKAP10 | 11216 | 1 | 2 | 33 | |
| GSE74704 | AKAP10 | 11216 | 2 | 1 | 17 | |
| TCGA | AKAP10 | 11216 | 18 | 24 | 54 |
Total number of gains: 82; Total number of losses: 50; Total Number of normals: 356.
Somatic mutations of AKAP10:
Generating mutation plots.
Highly correlated genes for AKAP10:
Showing top 20/68 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AKAP10 | ERVW-1 | 0.844413 | 3 | 0 | 3 |
| AKAP10 | EMB | 0.753914 | 3 | 0 | 3 |
| AKAP10 | NT5E | 0.725172 | 3 | 0 | 3 |
| AKAP10 | SFSWAP | 0.71394 | 3 | 0 | 3 |
| AKAP10 | TBCK | 0.707456 | 3 | 0 | 3 |
| AKAP10 | EHBP1L1 | 0.698072 | 3 | 0 | 3 |
| AKAP10 | ING3 | 0.691565 | 3 | 0 | 3 |
| AKAP10 | BRD2 | 0.691494 | 3 | 0 | 3 |
| AKAP10 | NGRN | 0.69127 | 3 | 0 | 3 |
| AKAP10 | PRKACB | 0.677947 | 3 | 0 | 3 |
| AKAP10 | LRIG2 | 0.677916 | 3 | 0 | 3 |
| AKAP10 | MCM8 | 0.669187 | 3 | 0 | 3 |
| AKAP10 | RFX5 | 0.667986 | 3 | 0 | 3 |
| AKAP10 | ZSCAN29 | 0.667733 | 3 | 0 | 3 |
| AKAP10 | HNRNPH1 | 0.665429 | 3 | 0 | 3 |
| AKAP10 | EID1 | 0.66441 | 3 | 0 | 3 |
| AKAP10 | CUL2 | 0.661527 | 3 | 0 | 3 |
| AKAP10 | PCMTD2 | 0.660596 | 3 | 0 | 3 |
| AKAP10 | ZNF704 | 0.659884 | 3 | 0 | 3 |
| AKAP10 | FAM76B | 0.65404 | 4 | 0 | 3 |
For details and further investigation, click here
