| Full name: leucine rich repeats and immunoglobulin like domains 2 | Alias Symbol: KIAA0806 | ||
| Type: protein-coding gene | Cytoband: 1p13.2 | ||
| Entrez ID: 9860 | HGNC ID: HGNC:20889 | Ensembl Gene: ENSG00000198799 | OMIM ID: 608869 |
| Drug and gene relationship at DGIdb | |||
Expression of LRIG2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRIG2 | 9860 | 238653_at | 0.4588 | 0.4154 | |
| GSE20347 | LRIG2 | 9860 | 205953_at | 0.3096 | 0.0021 | |
| GSE23400 | LRIG2 | 9860 | 205953_at | 0.3460 | 0.0000 | |
| GSE26886 | LRIG2 | 9860 | 238653_at | -0.3558 | 0.3232 | |
| GSE29001 | LRIG2 | 9860 | 205953_at | 0.3629 | 0.0271 | |
| GSE38129 | LRIG2 | 9860 | 205953_at | 0.4246 | 0.0000 | |
| GSE45670 | LRIG2 | 9860 | 238653_at | 0.0100 | 0.9656 | |
| GSE53622 | LRIG2 | 9860 | 48766 | 0.1126 | 0.1654 | |
| GSE53624 | LRIG2 | 9860 | 138462 | 0.2245 | 0.0010 | |
| GSE63941 | LRIG2 | 9860 | 238653_at | -0.5658 | 0.3039 | |
| GSE77861 | LRIG2 | 9860 | 205953_at | 0.2467 | 0.2373 | |
| GSE97050 | LRIG2 | 9860 | A_23_P160869 | 0.1633 | 0.5017 | |
| SRP007169 | LRIG2 | 9860 | RNAseq | 0.7757 | 0.0624 | |
| SRP008496 | LRIG2 | 9860 | RNAseq | 0.7113 | 0.0042 | |
| SRP064894 | LRIG2 | 9860 | RNAseq | 0.2738 | 0.1830 | |
| SRP133303 | LRIG2 | 9860 | RNAseq | 0.1025 | 0.3341 | |
| SRP159526 | LRIG2 | 9860 | RNAseq | -0.1581 | 0.6974 | |
| SRP193095 | LRIG2 | 9860 | RNAseq | 0.0895 | 0.2097 | |
| SRP219564 | LRIG2 | 9860 | RNAseq | 0.0234 | 0.9543 | |
| TCGA | LRIG2 | 9860 | RNAseq | 0.0098 | 0.8720 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LRIG2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRIG2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRIG2 | 9860 | 0 | 10 | 20 | |
| GSE20123 | LRIG2 | 9860 | 0 | 10 | 20 | |
| GSE43470 | LRIG2 | 9860 | 0 | 8 | 35 | |
| GSE46452 | LRIG2 | 9860 | 2 | 1 | 56 | |
| GSE47630 | LRIG2 | 9860 | 9 | 5 | 26 | |
| GSE54993 | LRIG2 | 9860 | 0 | 1 | 69 | |
| GSE54994 | LRIG2 | 9860 | 7 | 3 | 43 | |
| GSE60625 | LRIG2 | 9860 | 0 | 0 | 11 | |
| GSE74703 | LRIG2 | 9860 | 0 | 7 | 29 | |
| GSE74704 | LRIG2 | 9860 | 0 | 6 | 14 | |
| TCGA | LRIG2 | 9860 | 8 | 27 | 61 |
Total number of gains: 26; Total number of losses: 78; Total Number of normals: 384.
Somatic mutations of LRIG2:
Generating mutation plots.
Highly correlated genes for LRIG2:
Showing top 20/518 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRIG2 | FUBP1 | 0.77546 | 5 | 0 | 5 |
| LRIG2 | DOLK | 0.748016 | 3 | 0 | 3 |
| LRIG2 | TMEM170A | 0.729332 | 3 | 0 | 3 |
| LRIG2 | PDRG1 | 0.704599 | 3 | 0 | 3 |
| LRIG2 | IFRD2 | 0.700761 | 3 | 0 | 3 |
| LRIG2 | ALG2 | 0.692872 | 3 | 0 | 3 |
| LRIG2 | RPRD1B | 0.69019 | 3 | 0 | 3 |
| LRIG2 | KIAA1522 | 0.688823 | 3 | 0 | 3 |
| LRIG2 | NPHP4 | 0.685354 | 3 | 0 | 3 |
| LRIG2 | TPCN2 | 0.684121 | 3 | 0 | 3 |
| LRIG2 | MOB3C | 0.682808 | 3 | 0 | 3 |
| LRIG2 | TSPAN17 | 0.682245 | 3 | 0 | 3 |
| LRIG2 | TPM3 | 0.680855 | 3 | 0 | 3 |
| LRIG2 | ACACA | 0.680371 | 3 | 0 | 3 |
| LRIG2 | SCAF4 | 0.680115 | 4 | 0 | 3 |
| LRIG2 | NAA25 | 0.679105 | 3 | 0 | 3 |
| LRIG2 | IFT80 | 0.678856 | 4 | 0 | 3 |
| LRIG2 | AKAP10 | 0.677916 | 3 | 0 | 3 |
| LRIG2 | AZIN1 | 0.672523 | 3 | 0 | 3 |
| LRIG2 | IRF9 | 0.672144 | 4 | 0 | 3 |
For details and further investigation, click here
