| Full name: 5'-nucleotidase ecto | Alias Symbol: CD73|eN|eNT|CALJA | ||
| Type: protein-coding gene | Cytoband: 6q14.3 | ||
| Entrez ID: 4907 | HGNC ID: HGNC:8021 | Ensembl Gene: ENSG00000135318 | OMIM ID: 129190 |
| Drug and gene relationship at DGIdb | |||
Expression of NT5E:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NT5E | 4907 | 203939_at | -0.1043 | 0.9323 | |
| GSE20347 | NT5E | 4907 | 203939_at | 0.6543 | 0.0272 | |
| GSE23400 | NT5E | 4907 | 203939_at | 0.2644 | 0.0106 | |
| GSE26886 | NT5E | 4907 | 203939_at | 1.2063 | 0.0099 | |
| GSE29001 | NT5E | 4907 | 203939_at | 0.9548 | 0.0294 | |
| GSE38129 | NT5E | 4907 | 203939_at | 0.1716 | 0.7021 | |
| GSE45670 | NT5E | 4907 | 203939_at | 0.0093 | 0.9936 | |
| GSE53622 | NT5E | 4907 | 44686 | 0.4358 | 0.0252 | |
| GSE53624 | NT5E | 4907 | 44686 | 1.0916 | 0.0000 | |
| GSE63941 | NT5E | 4907 | 203939_at | -3.4279 | 0.1237 | |
| GSE77861 | NT5E | 4907 | 203939_at | 0.5016 | 0.1440 | |
| GSE97050 | NT5E | 4907 | A_24_P354715 | 0.4211 | 0.1537 | |
| SRP007169 | NT5E | 4907 | RNAseq | 3.3697 | 0.0000 | |
| SRP008496 | NT5E | 4907 | RNAseq | 2.7886 | 0.0000 | |
| SRP064894 | NT5E | 4907 | RNAseq | 1.1759 | 0.0000 | |
| SRP133303 | NT5E | 4907 | RNAseq | 1.1106 | 0.0065 | |
| SRP159526 | NT5E | 4907 | RNAseq | -0.2351 | 0.6899 | |
| SRP193095 | NT5E | 4907 | RNAseq | 1.0107 | 0.0438 | |
| SRP219564 | NT5E | 4907 | RNAseq | 1.7719 | 0.0801 | |
| TCGA | NT5E | 4907 | RNAseq | 0.0607 | 0.7056 |
Upregulated datasets: 7; Downregulated datasets: 0.
Survival by NT5E expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NT5E:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NT5E | 4907 | 1 | 4 | 25 | |
| GSE20123 | NT5E | 4907 | 1 | 3 | 26 | |
| GSE43470 | NT5E | 4907 | 2 | 1 | 40 | |
| GSE46452 | NT5E | 4907 | 2 | 11 | 46 | |
| GSE47630 | NT5E | 4907 | 8 | 6 | 26 | |
| GSE54993 | NT5E | 4907 | 3 | 2 | 65 | |
| GSE54994 | NT5E | 4907 | 8 | 8 | 37 | |
| GSE60625 | NT5E | 4907 | 0 | 1 | 10 | |
| GSE74703 | NT5E | 4907 | 2 | 1 | 33 | |
| GSE74704 | NT5E | 4907 | 0 | 2 | 18 | |
| TCGA | NT5E | 4907 | 6 | 21 | 69 |
Total number of gains: 33; Total number of losses: 60; Total Number of normals: 395.
Somatic mutations of NT5E:
Generating mutation plots.
Highly correlated genes for NT5E:
Showing top 20/986 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NT5E | HNRNPUL2 | 0.780523 | 3 | 0 | 3 |
| NT5E | TMTC1 | 0.734739 | 3 | 0 | 3 |
| NT5E | AKAP10 | 0.725172 | 3 | 0 | 3 |
| NT5E | RNASE4 | 0.725042 | 3 | 0 | 3 |
| NT5E | S1PR1 | 0.722053 | 3 | 0 | 3 |
| NT5E | TMX3 | 0.719914 | 3 | 0 | 3 |
| NT5E | ATXN1L | 0.714773 | 3 | 0 | 3 |
| NT5E | LRRC8C | 0.714173 | 4 | 0 | 4 |
| NT5E | PHYH | 0.713161 | 3 | 0 | 3 |
| NT5E | EVL | 0.711554 | 3 | 0 | 3 |
| NT5E | TCEA2 | 0.702295 | 3 | 0 | 3 |
| NT5E | TMEM138 | 0.700384 | 3 | 0 | 3 |
| NT5E | ZDHHC4 | 0.695359 | 4 | 0 | 3 |
| NT5E | MMRN1 | 0.69511 | 3 | 0 | 3 |
| NT5E | VPS18 | 0.694136 | 3 | 0 | 3 |
| NT5E | ATP11C | 0.693273 | 4 | 0 | 3 |
| NT5E | FAM20B | 0.692994 | 3 | 0 | 3 |
| NT5E | PPIF | 0.687773 | 3 | 0 | 3 |
| NT5E | TM4SF18 | 0.687583 | 4 | 0 | 4 |
| NT5E | GNB4 | 0.683602 | 3 | 0 | 3 |
For details and further investigation, click here
