| Full name: embigin | Alias Symbol: MGC71745 | ||
| Type: protein-coding gene | Cytoband: 5q11.1 | ||
| Entrez ID: 133418 | HGNC ID: HGNC:30465 | Ensembl Gene: ENSG00000170571 | OMIM ID: 615669 |
| Drug and gene relationship at DGIdb | |||
Expression of EMB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EMB | 133418 | 226789_at | 0.1718 | 0.8585 | |
| GSE26886 | EMB | 133418 | 226789_at | 0.0264 | 0.9669 | |
| GSE45670 | EMB | 133418 | 226789_at | -0.4192 | 0.1747 | |
| GSE53622 | EMB | 133418 | 12069 | -0.1678 | 0.2942 | |
| GSE53624 | EMB | 133418 | 30205 | -0.0854 | 0.6454 | |
| GSE63941 | EMB | 133418 | 226789_at | 2.7120 | 0.0388 | |
| GSE77861 | EMB | 133418 | 226789_at | 0.2564 | 0.6395 | |
| GSE97050 | EMB | 133418 | A_33_P3359900 | 0.9360 | 0.1646 | |
| SRP007169 | EMB | 133418 | RNAseq | 0.4093 | 0.3469 | |
| SRP008496 | EMB | 133418 | RNAseq | 0.0373 | 0.9134 | |
| SRP064894 | EMB | 133418 | RNAseq | 0.1972 | 0.4784 | |
| SRP133303 | EMB | 133418 | RNAseq | -0.0824 | 0.7793 | |
| SRP159526 | EMB | 133418 | RNAseq | -0.6639 | 0.3220 | |
| SRP193095 | EMB | 133418 | RNAseq | -0.4139 | 0.1717 | |
| SRP219564 | EMB | 133418 | RNAseq | 0.3239 | 0.5554 | |
| TCGA | EMB | 133418 | RNAseq | -0.0010 | 0.9952 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by EMB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EMB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EMB | 133418 | 3 | 9 | 18 | |
| GSE20123 | EMB | 133418 | 3 | 9 | 18 | |
| GSE43470 | EMB | 133418 | 1 | 13 | 29 | |
| GSE46452 | EMB | 133418 | 5 | 22 | 32 | |
| GSE47630 | EMB | 133418 | 2 | 16 | 22 | |
| GSE54993 | EMB | 133418 | 8 | 1 | 61 | |
| GSE54994 | EMB | 133418 | 6 | 15 | 32 | |
| GSE60625 | EMB | 133418 | 0 | 0 | 11 | |
| GSE74703 | EMB | 133418 | 1 | 10 | 25 | |
| GSE74704 | EMB | 133418 | 3 | 4 | 13 | |
| TCGA | EMB | 133418 | 47 | 19 | 30 |
Total number of gains: 79; Total number of losses: 118; Total Number of normals: 291.
Somatic mutations of EMB:
Generating mutation plots.
Highly correlated genes for EMB:
Showing top 20/218 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EMB | FAM76B | 0.788059 | 3 | 0 | 3 |
| EMB | PRDX3 | 0.770235 | 3 | 0 | 3 |
| EMB | AKAP10 | 0.753914 | 3 | 0 | 3 |
| EMB | TNFSF8 | 0.752481 | 3 | 0 | 3 |
| EMB | NNT | 0.7507 | 3 | 0 | 3 |
| EMB | TRUB1 | 0.739978 | 3 | 0 | 3 |
| EMB | TMEM126B | 0.732858 | 3 | 0 | 3 |
| EMB | POLG | 0.717807 | 3 | 0 | 3 |
| EMB | ALG8 | 0.711641 | 4 | 0 | 3 |
| EMB | PARVG | 0.709874 | 3 | 0 | 3 |
| EMB | GIMAP5 | 0.704921 | 3 | 0 | 3 |
| EMB | PLCB2 | 0.703931 | 3 | 0 | 3 |
| EMB | DCK | 0.703653 | 3 | 0 | 3 |
| EMB | RMND1 | 0.703314 | 3 | 0 | 3 |
| EMB | TSPAN3 | 0.697823 | 3 | 0 | 3 |
| EMB | CD96 | 0.695049 | 3 | 0 | 3 |
| EMB | C10orf88 | 0.694564 | 3 | 0 | 3 |
| EMB | PAK1 | 0.68714 | 3 | 0 | 3 |
| EMB | ARHGAP15 | 0.686901 | 3 | 0 | 3 |
| EMB | CD226 | 0.684568 | 3 | 0 | 3 |
For details and further investigation, click here
