| Full name: heterogeneous nuclear ribonucleoprotein H1 | Alias Symbol: hnRNPH | ||
| Type: protein-coding gene | Cytoband: 5q35.3 | ||
| Entrez ID: 3187 | HGNC ID: HGNC:5041 | Ensembl Gene: ENSG00000169045 | OMIM ID: 601035 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of HNRNPH1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE26886 | HNRNPH1 | 3187 | 201031_s_at | -0.7412 | 0.0002 | |
| GSE29001 | HNRNPH1 | 3187 | 201031_s_at | 0.1560 | 0.4274 | |
| GSE45670 | HNRNPH1 | 3187 | 201031_s_at | 0.1216 | 0.1823 | |
| GSE53622 | HNRNPH1 | 3187 | 2812 | 0.0787 | 0.1575 | |
| GSE53624 | HNRNPH1 | 3187 | 2812 | 0.1693 | 0.0001 | |
| GSE97050 | HNRNPH1 | 3187 | A_24_P320254 | -0.0675 | 0.8060 | |
| SRP007169 | HNRNPH1 | 3187 | RNAseq | 0.2877 | 0.4248 | |
| SRP008496 | HNRNPH1 | 3187 | RNAseq | 0.1532 | 0.4346 | |
| SRP064894 | HNRNPH1 | 3187 | RNAseq | 0.1378 | 0.4799 | |
| SRP133303 | HNRNPH1 | 3187 | RNAseq | 0.1564 | 0.0522 | |
| SRP159526 | HNRNPH1 | 3187 | RNAseq | 0.0435 | 0.7615 | |
| SRP193095 | HNRNPH1 | 3187 | RNAseq | 0.0011 | 0.9921 | |
| SRP219564 | HNRNPH1 | 3187 | RNAseq | 0.2508 | 0.3780 | |
| TCGA | HNRNPH1 | 3187 | RNAseq | 0.0638 | 0.1277 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HNRNPH1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HNRNPH1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HNRNPH1 | 3187 | 2 | 12 | 16 | |
| GSE20123 | HNRNPH1 | 3187 | 2 | 12 | 16 | |
| GSE43470 | HNRNPH1 | 3187 | 1 | 11 | 31 | |
| GSE46452 | HNRNPH1 | 3187 | 0 | 27 | 32 | |
| GSE47630 | HNRNPH1 | 3187 | 1 | 20 | 19 | |
| GSE54993 | HNRNPH1 | 3187 | 10 | 2 | 58 | |
| GSE54994 | HNRNPH1 | 3187 | 2 | 17 | 34 | |
| GSE60625 | HNRNPH1 | 3187 | 1 | 0 | 10 | |
| GSE74703 | HNRNPH1 | 3187 | 1 | 7 | 28 | |
| GSE74704 | HNRNPH1 | 3187 | 1 | 6 | 13 | |
| TCGA | HNRNPH1 | 3187 | 11 | 34 | 51 |
Total number of gains: 32; Total number of losses: 148; Total Number of normals: 308.
Somatic mutations of HNRNPH1:
Generating mutation plots.
Highly correlated genes for HNRNPH1:
Showing top 20/61 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HNRNPH1 | RPS9 | 0.735214 | 3 | 0 | 3 |
| HNRNPH1 | PRKAR1A | 0.727514 | 3 | 0 | 3 |
| HNRNPH1 | ACSL3 | 0.706802 | 3 | 0 | 3 |
| HNRNPH1 | TMED2 | 0.701612 | 3 | 0 | 3 |
| HNRNPH1 | LEPROT | 0.699287 | 3 | 0 | 3 |
| HNRNPH1 | DDX3X | 0.698195 | 3 | 0 | 3 |
| HNRNPH1 | CD63 | 0.695965 | 3 | 0 | 3 |
| HNRNPH1 | KEAP1 | 0.693585 | 3 | 0 | 3 |
| HNRNPH1 | PAIP2 | 0.693478 | 3 | 0 | 3 |
| HNRNPH1 | UBL5 | 0.690079 | 3 | 0 | 3 |
| HNRNPH1 | KPNA3 | 0.68995 | 3 | 0 | 3 |
| HNRNPH1 | SRRM1 | 0.689182 | 4 | 0 | 3 |
| HNRNPH1 | PHB | 0.687276 | 3 | 0 | 3 |
| HNRNPH1 | DAZAP2 | 0.677889 | 3 | 0 | 3 |
| HNRNPH1 | SPCS1 | 0.670514 | 3 | 0 | 3 |
| HNRNPH1 | RNF146 | 0.667165 | 3 | 0 | 3 |
| HNRNPH1 | AKAP10 | 0.665429 | 3 | 0 | 3 |
| HNRNPH1 | MCPH1 | 0.660994 | 3 | 0 | 3 |
| HNRNPH1 | MSH2 | 0.659566 | 3 | 0 | 3 |
| HNRNPH1 | NUDT21 | 0.655946 | 3 | 0 | 3 |
For details and further investigation, click here
