| Full name: protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 | Alias Symbol: FLJ10883 | ||
| Type: protein-coding gene | Cytoband: 20q13.33 | ||
| Entrez ID: 55251 | HGNC ID: HGNC:15882 | Ensembl Gene: ENSG00000203880 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of PCMTD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PCMTD2 | 55251 | 212406_s_at | 0.0047 | 0.9954 | |
| GSE20347 | PCMTD2 | 55251 | 212406_s_at | 0.2958 | 0.0563 | |
| GSE23400 | PCMTD2 | 55251 | 212406_s_at | 0.3367 | 0.0008 | |
| GSE26886 | PCMTD2 | 55251 | 212406_s_at | -0.1029 | 0.8005 | |
| GSE29001 | PCMTD2 | 55251 | 212406_s_at | 0.4446 | 0.1551 | |
| GSE38129 | PCMTD2 | 55251 | 212406_s_at | 0.2338 | 0.0919 | |
| GSE45670 | PCMTD2 | 55251 | 212406_s_at | -0.0928 | 0.5908 | |
| GSE53622 | PCMTD2 | 55251 | 9023 | 0.0165 | 0.8822 | |
| GSE53624 | PCMTD2 | 55251 | 9023 | -0.0139 | 0.9178 | |
| GSE63941 | PCMTD2 | 55251 | 212406_s_at | 0.2903 | 0.6020 | |
| GSE77861 | PCMTD2 | 55251 | 212406_s_at | 0.1019 | 0.7386 | |
| GSE97050 | PCMTD2 | A_21_P0012528 | -0.0237 | 0.9191 | ||
| SRP007169 | PCMTD2 | 55251 | RNAseq | 0.1161 | 0.7257 | |
| SRP008496 | PCMTD2 | 55251 | RNAseq | 0.5241 | 0.0462 | |
| SRP064894 | PCMTD2 | 55251 | RNAseq | 0.0467 | 0.8217 | |
| SRP133303 | PCMTD2 | 55251 | RNAseq | 0.0163 | 0.9122 | |
| SRP159526 | PCMTD2 | 55251 | RNAseq | 0.1424 | 0.6923 | |
| SRP193095 | PCMTD2 | 55251 | RNAseq | -0.0965 | 0.3633 | |
| SRP219564 | PCMTD2 | 55251 | RNAseq | 0.2186 | 0.6146 | |
| TCGA | PCMTD2 | 55251 | RNAseq | 0.0092 | 0.8665 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PCMTD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PCMTD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PCMTD2 | 55251 | 12 | 3 | 15 | |
| GSE20123 | PCMTD2 | 55251 | 12 | 3 | 15 | |
| GSE43470 | PCMTD2 | 55251 | 11 | 1 | 31 | |
| GSE46452 | PCMTD2 | 55251 | 35 | 0 | 24 | |
| GSE47630 | PCMTD2 | 55251 | 25 | 1 | 14 | |
| GSE54993 | PCMTD2 | 55251 | 0 | 17 | 53 | |
| GSE54994 | PCMTD2 | 55251 | 29 | 0 | 24 | |
| GSE60625 | PCMTD2 | 55251 | 0 | 0 | 11 | |
| GSE74703 | PCMTD2 | 55251 | 10 | 0 | 26 | |
| GSE74704 | PCMTD2 | 55251 | 9 | 1 | 10 | |
| TCGA | PCMTD2 | 55251 | 44 | 4 | 48 |
Total number of gains: 187; Total number of losses: 30; Total Number of normals: 271.
Somatic mutations of PCMTD2:
Generating mutation plots.
Highly correlated genes for PCMTD2:
Showing top 20/363 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PCMTD2 | SAMM50 | 0.771807 | 3 | 0 | 3 |
| PCMTD2 | UBR3 | 0.754607 | 3 | 0 | 3 |
| PCMTD2 | SUN1 | 0.750703 | 3 | 0 | 3 |
| PCMTD2 | BIVM | 0.725235 | 3 | 0 | 3 |
| PCMTD2 | NR2C2 | 0.719693 | 3 | 0 | 3 |
| PCMTD2 | MAPK1 | 0.71827 | 3 | 0 | 3 |
| PCMTD2 | SDHB | 0.716966 | 3 | 0 | 3 |
| PCMTD2 | MITD1 | 0.709803 | 4 | 0 | 4 |
| PCMTD2 | ANKRD28 | 0.694491 | 3 | 0 | 3 |
| PCMTD2 | DECR1 | 0.694094 | 4 | 0 | 4 |
| PCMTD2 | WDFY1 | 0.692643 | 3 | 0 | 3 |
| PCMTD2 | ANKRD50 | 0.688052 | 4 | 0 | 4 |
| PCMTD2 | VGLL4 | 0.677536 | 3 | 0 | 3 |
| PCMTD2 | ZNF573 | 0.675469 | 3 | 0 | 3 |
| PCMTD2 | PTCD2 | 0.67444 | 3 | 0 | 3 |
| PCMTD2 | TBC1D15 | 0.673881 | 5 | 0 | 5 |
| PCMTD2 | TBC1D23 | 0.671153 | 3 | 0 | 3 |
| PCMTD2 | SLC30A5 | 0.667389 | 5 | 0 | 4 |
| PCMTD2 | MAP1LC3B | 0.665851 | 3 | 0 | 3 |
| PCMTD2 | CLEC2B | 0.664748 | 4 | 0 | 3 |
For details and further investigation, click here
