| Full name: A-kinase anchoring protein 3 | Alias Symbol: FSP95|SOB1|AKAP110|CT82 | ||
| Type: protein-coding gene | Cytoband: 12p13.32 | ||
| Entrez ID: 10566 | HGNC ID: HGNC:373 | Ensembl Gene: ENSG00000111254 | OMIM ID: 604689 |
| Drug and gene relationship at DGIdb | |||
Expression of AKAP3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AKAP3 | 10566 | 207344_at | -0.1307 | 0.6958 | |
| GSE20347 | AKAP3 | 10566 | 207344_at | 0.0115 | 0.9052 | |
| GSE23400 | AKAP3 | 10566 | 207344_at | -0.1134 | 0.0097 | |
| GSE26886 | AKAP3 | 10566 | 207344_at | -0.1385 | 0.3762 | |
| GSE29001 | AKAP3 | 10566 | 207344_at | -0.0546 | 0.7474 | |
| GSE38129 | AKAP3 | 10566 | 207344_at | -0.1386 | 0.1556 | |
| GSE45670 | AKAP3 | 10566 | 207344_at | 0.0786 | 0.4622 | |
| GSE53622 | AKAP3 | 10566 | 67784 | -0.0358 | 0.7529 | |
| GSE53624 | AKAP3 | 10566 | 67784 | -0.0771 | 0.4895 | |
| GSE63941 | AKAP3 | 10566 | 207344_at | 0.3145 | 0.1028 | |
| GSE77861 | AKAP3 | 10566 | 207344_at | 0.0704 | 0.6996 | |
| SRP159526 | AKAP3 | 10566 | RNAseq | 0.4113 | 0.5908 | |
| TCGA | AKAP3 | 10566 | RNAseq | -0.4914 | 0.1096 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by AKAP3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AKAP3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AKAP3 | 10566 | 6 | 4 | 20 | |
| GSE20123 | AKAP3 | 10566 | 6 | 4 | 20 | |
| GSE43470 | AKAP3 | 10566 | 9 | 3 | 31 | |
| GSE46452 | AKAP3 | 10566 | 10 | 1 | 48 | |
| GSE47630 | AKAP3 | 10566 | 12 | 2 | 26 | |
| GSE54993 | AKAP3 | 10566 | 1 | 10 | 59 | |
| GSE54994 | AKAP3 | 10566 | 10 | 2 | 41 | |
| GSE60625 | AKAP3 | 10566 | 0 | 1 | 10 | |
| GSE74703 | AKAP3 | 10566 | 8 | 2 | 26 | |
| GSE74704 | AKAP3 | 10566 | 4 | 2 | 14 | |
| TCGA | AKAP3 | 10566 | 40 | 6 | 50 |
Total number of gains: 106; Total number of losses: 37; Total Number of normals: 345.
Somatic mutations of AKAP3:
Generating mutation plots.
Highly correlated genes for AKAP3:
Showing top 20/107 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AKAP3 | NSUN7 | 0.680788 | 3 | 0 | 3 |
| AKAP3 | PIPOX | 0.64692 | 3 | 0 | 3 |
| AKAP3 | BLK | 0.642406 | 3 | 0 | 3 |
| AKAP3 | KRT2 | 0.640868 | 3 | 0 | 3 |
| AKAP3 | OR2S2 | 0.633443 | 3 | 0 | 3 |
| AKAP3 | FXYD6 | 0.630762 | 3 | 0 | 3 |
| AKAP3 | PAK3 | 0.629361 | 3 | 0 | 3 |
| AKAP3 | PAX7 | 0.620183 | 4 | 0 | 3 |
| AKAP3 | CILP2 | 0.618016 | 3 | 0 | 3 |
| AKAP3 | PEAK1 | 0.616633 | 3 | 0 | 3 |
| AKAP3 | RNASE4 | 0.614558 | 3 | 0 | 3 |
| AKAP3 | SLC2A5 | 0.611055 | 4 | 0 | 3 |
| AKAP3 | SLC17A7 | 0.610865 | 6 | 0 | 5 |
| AKAP3 | ZNF835 | 0.61034 | 6 | 0 | 4 |
| AKAP3 | TSPO2 | 0.607237 | 4 | 0 | 3 |
| AKAP3 | VWA1 | 0.607225 | 3 | 0 | 3 |
| AKAP3 | JAK3 | 0.603942 | 5 | 0 | 4 |
| AKAP3 | SLCO5A1 | 0.601889 | 3 | 0 | 3 |
| AKAP3 | LGALS13 | 0.596125 | 4 | 0 | 3 |
| AKAP3 | OLFM1 | 0.594509 | 5 | 0 | 4 |
For details and further investigation, click here
