| Full name: paired box 7 | Alias Symbol: Hup1 | ||
| Type: protein-coding gene | Cytoband: 1p36.13 | ||
| Entrez ID: 5081 | HGNC ID: HGNC:8621 | Ensembl Gene: ENSG00000009709 | OMIM ID: 167410 |
| Drug and gene relationship at DGIdb | |||
Expression of PAX7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PAX7 | 5081 | 208060_at | -0.1504 | 0.6084 | |
| GSE20347 | PAX7 | 5081 | 208060_at | -0.1131 | 0.2239 | |
| GSE23400 | PAX7 | 5081 | 208060_at | -0.0929 | 0.0019 | |
| GSE26886 | PAX7 | 5081 | 208060_at | 0.0666 | 0.5731 | |
| GSE29001 | PAX7 | 5081 | 208060_at | -0.2885 | 0.0371 | |
| GSE38129 | PAX7 | 5081 | 208060_at | -0.1318 | 0.0637 | |
| GSE45670 | PAX7 | 5081 | 208060_at | 0.0667 | 0.4849 | |
| GSE53622 | PAX7 | 5081 | 50276 | 0.6856 | 0.0000 | |
| GSE53624 | PAX7 | 5081 | 50276 | 0.5144 | 0.0000 | |
| GSE63941 | PAX7 | 5081 | 208060_at | 0.2340 | 0.2766 | |
| GSE77861 | PAX7 | 5081 | 208060_at | -0.0522 | 0.6898 | |
| GSE97050 | PAX7 | 5081 | A_23_P500985 | -0.0712 | 0.7682 | |
| TCGA | PAX7 | 5081 | RNAseq | 3.8585 | 0.0003 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by PAX7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PAX7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PAX7 | 5081 | 0 | 5 | 25 | |
| GSE20123 | PAX7 | 5081 | 0 | 4 | 26 | |
| GSE43470 | PAX7 | 5081 | 0 | 8 | 35 | |
| GSE46452 | PAX7 | 5081 | 5 | 1 | 53 | |
| GSE47630 | PAX7 | 5081 | 8 | 3 | 29 | |
| GSE54993 | PAX7 | 5081 | 3 | 1 | 66 | |
| GSE54994 | PAX7 | 5081 | 11 | 4 | 38 | |
| GSE60625 | PAX7 | 5081 | 0 | 0 | 11 | |
| GSE74703 | PAX7 | 5081 | 0 | 5 | 31 | |
| GSE74704 | PAX7 | 5081 | 0 | 0 | 20 | |
| TCGA | PAX7 | 5081 | 10 | 22 | 64 |
Total number of gains: 37; Total number of losses: 53; Total Number of normals: 398.
Somatic mutations of PAX7:
Generating mutation plots.
Highly correlated genes for PAX7:
Showing top 20/767 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PAX7 | CYB5D2 | 0.756578 | 3 | 0 | 3 |
| PAX7 | PTPRCAP | 0.738647 | 3 | 0 | 3 |
| PAX7 | HRC | 0.728107 | 5 | 0 | 5 |
| PAX7 | ABCC6 | 0.725434 | 3 | 0 | 3 |
| PAX7 | IL9R | 0.719659 | 6 | 0 | 6 |
| PAX7 | NTNG2 | 0.716288 | 3 | 0 | 3 |
| PAX7 | ALAS2 | 0.711898 | 4 | 0 | 4 |
| PAX7 | GPD1 | 0.710688 | 4 | 0 | 4 |
| PAX7 | ZNF835 | 0.708837 | 7 | 0 | 6 |
| PAX7 | CABP1 | 0.708736 | 4 | 0 | 4 |
| PAX7 | PHF7 | 0.706332 | 6 | 0 | 6 |
| PAX7 | GDF2 | 0.699453 | 3 | 0 | 3 |
| PAX7 | FAM189A1 | 0.699246 | 3 | 0 | 3 |
| PAX7 | DAO | 0.697736 | 5 | 0 | 5 |
| PAX7 | MUC8 | 0.696631 | 6 | 0 | 5 |
| PAX7 | PIWIL2 | 0.695484 | 6 | 0 | 6 |
| PAX7 | CLCNKB | 0.69091 | 4 | 0 | 4 |
| PAX7 | SIRPD | 0.689557 | 3 | 0 | 3 |
| PAX7 | PGC | 0.689269 | 4 | 0 | 3 |
| PAX7 | KRTAP5-9 | 0.689083 | 5 | 0 | 5 |
For details and further investigation, click here
