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Severity: Warning

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Filename: controllers/Result_pages.php

Line Number: 123

Backtrace:

File: /data/webapp/var/www/html/ESCCdb/application/controllers/Result_pages.php
Line: 123
Function: exec

File: /data/webapp/var/www/html/ESCCdb/application/controllers/Result_pages.php
Line: 387
Function: drawSurvPlot

File: /data/webapp/var/www/html/ESCCdb/index.php
Line: 315
Function: require_once

Multi-Omics Database of ESCC

 

OR2S2

 

Full name: olfactory receptor family 2 subfamily S member 2 (gene/pseudogene) Alias Symbol: 
Type: protein-coding gene Cytoband: 9p13.3
Entrez ID: 56656 HGNC ID: HGNC:8276 Ensembl Gene: ENSG00000278889 OMIM ID: 
Drug and gene relationship at DGIdb

 

OR2S2 involved pathways:

KEGG pathway Description View
hsa04740Olfactory transduction

 

Expression of OR2S2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 OR2S2 56656 221409_at 0.0449 0.8452
GSE20347 OR2S2 56656 221409_at 0.0452 0.5913
GSE23400 OR2S2 56656 221409_at -0.1065 0.0308
GSE26886 OR2S2 56656 221409_at -0.0444 0.7865
GSE29001 OR2S2 56656 221409_at -0.0714 0.7335
GSE38129 OR2S2 56656 221409_at -0.0015 0.9856
GSE45670 OR2S2 56656 221409_at 0.2482 0.0066
GSE63941 OR2S2 56656 221409_at 0.0722 0.6770
GSE77861 OR2S2 56656 221409_at 0.0063 0.9692

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by OR2S2 expression:

 

TCGA

 

Note: Click image to view full size file.  


Copy number change of OR2S2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 OR2S2 56656 3 12 15
GSE20123 OR2S2 56656 3 12 15
GSE43470 OR2S2 56656 3 10 30
GSE46452 OR2S2 56656 6 15 38
GSE47630 OR2S2 56656 1 20 19
GSE54993 OR2S2 56656 6 0 64
GSE54994 OR2S2 56656 5 12 36
GSE60625 OR2S2 56656 0 0 11
GSE74703 OR2S2 56656 2 7 27
GSE74704 OR2S2 56656 0 10 10
TCGA OR2S2 56656 16 44 36

Total number of gains: 45; Total number of losses: 142; Total Number of normals: 301.  


 

Somatic mutations of OR2S2:

 

Generating mutation plots.

 

Highly correlated genes for OR2S2:

 

Showing top 20/719 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
OR2S2GRIN2B0.73187403
OR2S2HRH40.711809404
OR2S2APOL50.698578303
OR2S2NOS10.69424404
OR2S2MCHR10.693297303
OR2S2TAS2R90.681427303
OR2S2MAGEA80.680751303
OR2S2SLC2A50.67984303
OR2S2TCP10L0.67799505
OR2S2CGA0.675381604
OR2S2DDX40.674854303
OR2S2CCR40.674815505
OR2S2SLC5A40.670974504
OR2S2DRD50.670077504
OR2S2GP20.664323404
OR2S2NTNG10.662571403
OR2S2GRM10.660971303
OR2S2KHDRBS20.659993403
OR2S2WNT8B0.659352404
OR2S2TRPM30.657909404

For details and further investigation, click here