| Full name: FXYD domain containing ion transport regulator 6 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11q23.3 | ||
| Entrez ID: 53826 | HGNC ID: HGNC:4030 | Ensembl Gene: ENSG00000137726 | OMIM ID: 606683 |
| Drug and gene relationship at DGIdb | |||
Expression of FXYD6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FXYD6 | 53826 | 217897_at | -0.8873 | 0.4068 | |
| GSE20347 | FXYD6 | 53826 | 217897_at | 0.4207 | 0.0707 | |
| GSE23400 | FXYD6 | 53826 | 217897_at | -0.2224 | 0.1353 | |
| GSE26886 | FXYD6 | 53826 | 217897_at | 0.5488 | 0.0675 | |
| GSE29001 | FXYD6 | 53826 | 217897_at | 0.4119 | 0.3605 | |
| GSE38129 | FXYD6 | 53826 | 217897_at | -0.0638 | 0.8833 | |
| GSE45670 | FXYD6 | 53826 | 217897_at | -1.2062 | 0.0001 | |
| GSE53622 | FXYD6 | 53826 | 37051 | -0.4042 | 0.0563 | |
| GSE53624 | FXYD6 | 53826 | 37051 | -0.0592 | 0.7146 | |
| GSE63941 | FXYD6 | 53826 | 217897_at | 0.5610 | 0.3539 | |
| GSE77861 | FXYD6 | 53826 | 217897_at | 0.2072 | 0.4715 | |
| GSE97050 | FXYD6 | 53826 | A_23_P150394 | -0.7617 | 0.1932 | |
| SRP007169 | FXYD6 | 53826 | RNAseq | 2.7922 | 0.0014 | |
| SRP064894 | FXYD6 | 53826 | RNAseq | -0.2794 | 0.4758 | |
| SRP133303 | FXYD6 | 53826 | RNAseq | -0.5955 | 0.0398 | |
| SRP159526 | FXYD6 | 53826 | RNAseq | 0.8307 | 0.0939 | |
| SRP193095 | FXYD6 | 53826 | RNAseq | 1.2911 | 0.0015 | |
| SRP219564 | FXYD6 | 53826 | RNAseq | -0.8174 | 0.4394 | |
| TCGA | FXYD6 | 53826 | RNAseq | -0.4062 | 0.0121 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by FXYD6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FXYD6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FXYD6 | 53826 | 1 | 11 | 18 | |
| GSE20123 | FXYD6 | 53826 | 1 | 11 | 18 | |
| GSE43470 | FXYD6 | 53826 | 2 | 9 | 32 | |
| GSE46452 | FXYD6 | 53826 | 3 | 26 | 30 | |
| GSE47630 | FXYD6 | 53826 | 2 | 19 | 19 | |
| GSE54993 | FXYD6 | 53826 | 10 | 0 | 60 | |
| GSE54994 | FXYD6 | 53826 | 5 | 19 | 29 | |
| GSE60625 | FXYD6 | 53826 | 0 | 3 | 8 | |
| GSE74703 | FXYD6 | 53826 | 1 | 6 | 29 | |
| GSE74704 | FXYD6 | 53826 | 0 | 7 | 13 | |
| TCGA | FXYD6 | 53826 | 5 | 50 | 41 |
Total number of gains: 30; Total number of losses: 161; Total Number of normals: 297.
Somatic mutations of FXYD6:
Generating mutation plots.
Highly correlated genes for FXYD6:
Showing top 20/950 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FXYD6 | DCHS1 | 0.799518 | 8 | 0 | 8 |
| FXYD6 | MYADM | 0.776676 | 4 | 0 | 4 |
| FXYD6 | SOBP | 0.771659 | 10 | 0 | 10 |
| FXYD6 | FGFR1 | 0.762187 | 6 | 0 | 6 |
| FXYD6 | PEG3 | 0.757259 | 5 | 0 | 5 |
| FXYD6 | LRRN4CL | 0.752888 | 6 | 0 | 6 |
| FXYD6 | FIBIN | 0.752633 | 4 | 0 | 3 |
| FXYD6 | PDE1A | 0.751887 | 8 | 0 | 8 |
| FXYD6 | TLN1 | 0.750947 | 5 | 0 | 5 |
| FXYD6 | TNFSF12 | 0.747876 | 3 | 0 | 3 |
| FXYD6 | KCNT2 | 0.745117 | 6 | 0 | 6 |
| FXYD6 | WSCD2 | 0.74193 | 3 | 0 | 3 |
| FXYD6 | CYS1 | 0.741769 | 6 | 0 | 6 |
| FXYD6 | CTSF | 0.7403 | 9 | 0 | 8 |
| FXYD6 | TMEM170B | 0.738329 | 6 | 0 | 5 |
| FXYD6 | RASSF2 | 0.737006 | 7 | 0 | 7 |
| FXYD6 | ANXA6 | 0.733662 | 10 | 0 | 9 |
| FXYD6 | HMCN1 | 0.733493 | 6 | 0 | 6 |
| FXYD6 | KANK2 | 0.732382 | 9 | 0 | 9 |
| FXYD6 | DMPK | 0.732128 | 5 | 0 | 4 |
For details and further investigation, click here
