| Full name: von Willebrand factor A domain containing 1 | Alias Symbol: FLJ22215|VWA-1|WARP | ||
| Type: protein-coding gene | Cytoband: 1p36.33 | ||
| Entrez ID: 64856 | HGNC ID: HGNC:30910 | Ensembl Gene: ENSG00000179403 | OMIM ID: 611901 |
| Drug and gene relationship at DGIdb | |||
Expression of VWA1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | VWA1 | 64856 | 218731_s_at | 0.1007 | 0.7379 | |
| GSE20347 | VWA1 | 64856 | 218731_s_at | 0.0659 | 0.7039 | |
| GSE23400 | VWA1 | 64856 | 218731_s_at | -0.0669 | 0.4070 | |
| GSE26886 | VWA1 | 64856 | 218731_s_at | 0.5722 | 0.0067 | |
| GSE29001 | VWA1 | 64856 | 218731_s_at | -0.1529 | 0.4403 | |
| GSE38129 | VWA1 | 64856 | 218731_s_at | -0.1442 | 0.4823 | |
| GSE45670 | VWA1 | 64856 | 218731_s_at | 0.2485 | 0.0227 | |
| GSE53622 | VWA1 | 64856 | 42726 | -0.1144 | 0.2403 | |
| GSE53624 | VWA1 | 64856 | 42726 | 0.0311 | 0.6679 | |
| GSE63941 | VWA1 | 64856 | 218731_s_at | 1.1388 | 0.0542 | |
| GSE77861 | VWA1 | 64856 | 218731_s_at | 0.0896 | 0.6566 | |
| GSE97050 | VWA1 | 64856 | A_33_P3395743 | 0.0157 | 0.9751 | |
| SRP007169 | VWA1 | 64856 | RNAseq | -1.2604 | 0.0043 | |
| SRP008496 | VWA1 | 64856 | RNAseq | -1.0743 | 0.0000 | |
| SRP064894 | VWA1 | 64856 | RNAseq | 0.4362 | 0.0977 | |
| SRP133303 | VWA1 | 64856 | RNAseq | 0.0097 | 0.9683 | |
| SRP159526 | VWA1 | 64856 | RNAseq | 0.0808 | 0.7906 | |
| SRP193095 | VWA1 | 64856 | RNAseq | 0.4528 | 0.0288 | |
| SRP219564 | VWA1 | 64856 | RNAseq | -0.3484 | 0.6572 | |
| TCGA | VWA1 | 64856 | RNAseq | -0.1118 | 0.1092 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by VWA1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of VWA1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | VWA1 | 64856 | 3 | 7 | 20 | |
| GSE20123 | VWA1 | 64856 | 3 | 6 | 21 | |
| GSE43470 | VWA1 | 64856 | 3 | 5 | 35 | |
| GSE46452 | VWA1 | 64856 | 7 | 1 | 51 | |
| GSE47630 | VWA1 | 64856 | 8 | 4 | 28 | |
| GSE54993 | VWA1 | 64856 | 2 | 2 | 66 | |
| GSE54994 | VWA1 | 64856 | 15 | 2 | 36 | |
| GSE60625 | VWA1 | 64856 | 0 | 0 | 11 | |
| GSE74703 | VWA1 | 64856 | 3 | 3 | 30 | |
| GSE74704 | VWA1 | 64856 | 3 | 0 | 17 | |
| TCGA | VWA1 | 64856 | 14 | 20 | 62 |
Total number of gains: 61; Total number of losses: 50; Total Number of normals: 377.
Somatic mutations of VWA1:
Generating mutation plots.
Highly correlated genes for VWA1:
Showing top 20/510 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| VWA1 | TUBG2 | 0.785407 | 3 | 0 | 3 |
| VWA1 | P4HTM | 0.741348 | 3 | 0 | 3 |
| VWA1 | ELFN1 | 0.737316 | 3 | 0 | 3 |
| VWA1 | DNAH11 | 0.721266 | 3 | 0 | 3 |
| VWA1 | TBC1D25 | 0.713606 | 3 | 0 | 3 |
| VWA1 | TSNARE1 | 0.712109 | 3 | 0 | 3 |
| VWA1 | DNAJB12 | 0.706081 | 3 | 0 | 3 |
| VWA1 | PPP1R16A | 0.703145 | 4 | 0 | 4 |
| VWA1 | ZMYM3 | 0.70154 | 4 | 0 | 4 |
| VWA1 | ACO1 | 0.69626 | 4 | 0 | 4 |
| VWA1 | KRTCAP2 | 0.696073 | 3 | 0 | 3 |
| VWA1 | RRAS | 0.692173 | 6 | 0 | 6 |
| VWA1 | SNAI3 | 0.691639 | 3 | 0 | 3 |
| VWA1 | TRIM47 | 0.691204 | 5 | 0 | 3 |
| VWA1 | MEPCE | 0.690877 | 3 | 0 | 3 |
| VWA1 | USP20 | 0.690838 | 4 | 0 | 4 |
| VWA1 | SNAPC4 | 0.687198 | 4 | 0 | 3 |
| VWA1 | PRKCSH | 0.684613 | 5 | 0 | 5 |
| VWA1 | DHDH | 0.684519 | 3 | 0 | 3 |
| VWA1 | LOXL4 | 0.683583 | 3 | 0 | 3 |
For details and further investigation, click here
