| Full name: aldehyde dehydrogenase 1 family member B1 | Alias Symbol: ALDHX | ||
| Type: protein-coding gene | Cytoband: 9p13.1 | ||
| Entrez ID: 219 | HGNC ID: HGNC:407 | Ensembl Gene: ENSG00000137124 | OMIM ID: 100670 |
| Drug and gene relationship at DGIdb | |||
Expression of ALDH1B1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ALDH1B1 | 219 | 209645_s_at | -0.6858 | 0.4323 | |
| GSE20347 | ALDH1B1 | 219 | 209646_x_at | 0.0734 | 0.5024 | |
| GSE23400 | ALDH1B1 | 219 | 209645_s_at | 0.1341 | 0.3337 | |
| GSE26886 | ALDH1B1 | 219 | 209645_s_at | 0.3034 | 0.0331 | |
| GSE29001 | ALDH1B1 | 219 | 209645_s_at | 0.0376 | 0.8339 | |
| GSE38129 | ALDH1B1 | 219 | 209646_x_at | -0.2012 | 0.2181 | |
| GSE45670 | ALDH1B1 | 219 | 209645_s_at | -0.2515 | 0.0479 | |
| GSE53622 | ALDH1B1 | 219 | 49169 | -0.0674 | 0.7350 | |
| GSE53624 | ALDH1B1 | 219 | 49169 | 0.1642 | 0.1941 | |
| GSE63941 | ALDH1B1 | 219 | 209646_x_at | 0.3525 | 0.2633 | |
| GSE77861 | ALDH1B1 | 219 | 209645_s_at | 0.0238 | 0.8452 | |
| GSE97050 | ALDH1B1 | 219 | A_24_P64233 | -0.4188 | 0.2206 | |
| SRP007169 | ALDH1B1 | 219 | RNAseq | 3.0509 | 0.0000 | |
| SRP008496 | ALDH1B1 | 219 | RNAseq | 3.5716 | 0.0000 | |
| SRP064894 | ALDH1B1 | 219 | RNAseq | 0.3183 | 0.3919 | |
| SRP133303 | ALDH1B1 | 219 | RNAseq | -0.0624 | 0.7341 | |
| SRP193095 | ALDH1B1 | 219 | RNAseq | 0.7271 | 0.0089 | |
| SRP219564 | ALDH1B1 | 219 | RNAseq | -0.5750 | 0.6031 | |
| TCGA | ALDH1B1 | 219 | RNAseq | -0.3332 | 0.0043 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by ALDH1B1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ALDH1B1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ALDH1B1 | 219 | 3 | 14 | 13 | |
| GSE20123 | ALDH1B1 | 219 | 3 | 14 | 13 | |
| GSE43470 | ALDH1B1 | 219 | 1 | 12 | 30 | |
| GSE46452 | ALDH1B1 | 219 | 6 | 15 | 38 | |
| GSE47630 | ALDH1B1 | 219 | 1 | 20 | 19 | |
| GSE54993 | ALDH1B1 | 219 | 6 | 0 | 64 | |
| GSE54994 | ALDH1B1 | 219 | 5 | 14 | 34 | |
| GSE60625 | ALDH1B1 | 219 | 0 | 0 | 11 | |
| GSE74703 | ALDH1B1 | 219 | 1 | 8 | 27 | |
| GSE74704 | ALDH1B1 | 219 | 0 | 10 | 10 | |
| TCGA | ALDH1B1 | 219 | 14 | 45 | 37 |
Total number of gains: 40; Total number of losses: 152; Total Number of normals: 296.
Somatic mutations of ALDH1B1:
Generating mutation plots.
Highly correlated genes for ALDH1B1:
Showing top 20/831 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ALDH1B1 | PDK3 | 0.805799 | 3 | 0 | 3 |
| ALDH1B1 | SYNC | 0.800361 | 4 | 0 | 4 |
| ALDH1B1 | ZEB1 | 0.794795 | 3 | 0 | 3 |
| ALDH1B1 | STARD9 | 0.761113 | 3 | 0 | 3 |
| ALDH1B1 | C16orf86 | 0.760177 | 3 | 0 | 3 |
| ALDH1B1 | SLC25A42 | 0.746115 | 3 | 0 | 3 |
| ALDH1B1 | NUDT16 | 0.745705 | 3 | 0 | 3 |
| ALDH1B1 | ADCY2 | 0.739806 | 5 | 0 | 5 |
| ALDH1B1 | PLEKHO1 | 0.72836 | 9 | 0 | 8 |
| ALDH1B1 | CD99L2 | 0.721683 | 4 | 0 | 4 |
| ALDH1B1 | TGFB1I1 | 0.714339 | 10 | 0 | 10 |
| ALDH1B1 | SDC3 | 0.709219 | 4 | 0 | 4 |
| ALDH1B1 | RAPGEF2 | 0.707792 | 3 | 0 | 3 |
| ALDH1B1 | PLAC9 | 0.707321 | 3 | 0 | 3 |
| ALDH1B1 | MSRB3 | 0.70401 | 6 | 0 | 5 |
| ALDH1B1 | PRKACB | 0.703501 | 5 | 0 | 5 |
| ALDH1B1 | PDLIM3 | 0.70307 | 10 | 0 | 8 |
| ALDH1B1 | PKD2 | 0.701796 | 7 | 0 | 6 |
| ALDH1B1 | CCDC69 | 0.700402 | 5 | 0 | 4 |
| ALDH1B1 | PACSIN2 | 0.700119 | 4 | 0 | 3 |
For details and further investigation, click here
