| Full name: pyruvate dehydrogenase kinase 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: Xp22.11 | ||
| Entrez ID: 5165 | HGNC ID: HGNC:8811 | Ensembl Gene: ENSG00000067992 | OMIM ID: 300906 |
| Drug and gene relationship at DGIdb | |||
Expression of PDK3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PDK3 | 5165 | 228959_at | -0.4045 | 0.5811 | |
| GSE20347 | PDK3 | 5165 | 221957_at | 0.2136 | 0.0865 | |
| GSE23400 | PDK3 | 5165 | 221957_at | 0.0148 | 0.8053 | |
| GSE26886 | PDK3 | 5165 | 228959_at | 0.5259 | 0.2175 | |
| GSE29001 | PDK3 | 5165 | 221957_at | -0.1067 | 0.6751 | |
| GSE38129 | PDK3 | 5165 | 221957_at | 0.2017 | 0.1137 | |
| GSE45670 | PDK3 | 5165 | 228959_at | -0.7927 | 0.0014 | |
| GSE53622 | PDK3 | 5165 | 25186 | -0.2912 | 0.0144 | |
| GSE53624 | PDK3 | 5165 | 25186 | -0.0710 | 0.4412 | |
| GSE63941 | PDK3 | 5165 | 228959_at | 0.9902 | 0.1616 | |
| GSE77861 | PDK3 | 5165 | 228959_at | 0.1663 | 0.6553 | |
| GSE97050 | PDK3 | 5165 | A_23_P250478 | -0.5943 | 0.2176 | |
| SRP007169 | PDK3 | 5165 | RNAseq | -0.7683 | 0.1368 | |
| SRP008496 | PDK3 | 5165 | RNAseq | -0.0432 | 0.8995 | |
| SRP064894 | PDK3 | 5165 | RNAseq | 0.1929 | 0.3577 | |
| SRP133303 | PDK3 | 5165 | RNAseq | 0.1097 | 0.6246 | |
| SRP159526 | PDK3 | 5165 | RNAseq | 0.2714 | 0.3165 | |
| SRP193095 | PDK3 | 5165 | RNAseq | -0.1603 | 0.1675 | |
| SRP219564 | PDK3 | 5165 | RNAseq | -0.0352 | 0.9478 | |
| TCGA | PDK3 | 5165 | RNAseq | -0.0469 | 0.6682 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PDK3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PDK3:
No record found for this gene.
Somatic mutations of PDK3:
Generating mutation plots.
Highly correlated genes for PDK3:
Showing top 20/474 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PDK3 | ALDH1B1 | 0.805799 | 3 | 0 | 3 |
| PDK3 | JPH2 | 0.791561 | 3 | 0 | 3 |
| PDK3 | NKX6-1 | 0.791494 | 3 | 0 | 3 |
| PDK3 | ANO6 | 0.788087 | 3 | 0 | 3 |
| PDK3 | PEG10 | 0.779394 | 3 | 0 | 3 |
| PDK3 | MLH3 | 0.772091 | 3 | 0 | 3 |
| PDK3 | PLIN4 | 0.769626 | 3 | 0 | 3 |
| PDK3 | TMEM167B | 0.763351 | 3 | 0 | 3 |
| PDK3 | LNP1 | 0.75809 | 3 | 0 | 3 |
| PDK3 | FNDC5 | 0.755425 | 3 | 0 | 3 |
| PDK3 | INTS10 | 0.754885 | 3 | 0 | 3 |
| PDK3 | MEF2D | 0.748801 | 4 | 0 | 4 |
| PDK3 | INTU | 0.747335 | 3 | 0 | 3 |
| PDK3 | RFC1 | 0.747273 | 3 | 0 | 3 |
| PDK3 | TMEM205 | 0.746013 | 3 | 0 | 3 |
| PDK3 | DDX50 | 0.744782 | 3 | 0 | 3 |
| PDK3 | ZNF510 | 0.742961 | 4 | 0 | 4 |
| PDK3 | SPOP | 0.74154 | 4 | 0 | 4 |
| PDK3 | ITPKB | 0.74044 | 3 | 0 | 3 |
| PDK3 | CSDE1 | 0.737495 | 4 | 0 | 3 |
For details and further investigation, click here
