| Full name: syndecan 3 | Alias Symbol: N-syndecan|SYND3 | ||
| Type: protein-coding gene | Cytoband: 1p35.2 | ||
| Entrez ID: 9672 | HGNC ID: HGNC:10660 | Ensembl Gene: ENSG00000162512 | OMIM ID: 186357 |
| Drug and gene relationship at DGIdb | |||
Expression of SDC3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SDC3 | 9672 | 202898_at | 0.4284 | 0.5194 | |
| GSE20347 | SDC3 | 9672 | 202898_at | 0.5926 | 0.0000 | |
| GSE23400 | SDC3 | 9672 | 202898_at | 0.1058 | 0.2699 | |
| GSE26886 | SDC3 | 9672 | 202898_at | 0.3140 | 0.0092 | |
| GSE29001 | SDC3 | 9672 | 202898_at | 0.6700 | 0.0013 | |
| GSE38129 | SDC3 | 9672 | 202898_at | 0.2258 | 0.5555 | |
| GSE45670 | SDC3 | 9672 | 202898_at | -0.0040 | 0.9893 | |
| GSE53622 | SDC3 | 9672 | 76438 | -0.0442 | 0.6715 | |
| GSE53624 | SDC3 | 9672 | 76438 | -0.0619 | 0.4721 | |
| GSE63941 | SDC3 | 9672 | 202898_at | -1.5397 | 0.0033 | |
| GSE77861 | SDC3 | 9672 | 202898_at | 0.5030 | 0.0231 | |
| GSE97050 | SDC3 | 9672 | A_33_P3241884 | -0.1646 | 0.7274 | |
| SRP007169 | SDC3 | 9672 | RNAseq | 3.7673 | 0.0000 | |
| SRP008496 | SDC3 | 9672 | RNAseq | 3.1948 | 0.0000 | |
| SRP064894 | SDC3 | 9672 | RNAseq | 0.6158 | 0.0320 | |
| SRP133303 | SDC3 | 9672 | RNAseq | 0.5747 | 0.0339 | |
| SRP159526 | SDC3 | 9672 | RNAseq | 0.5863 | 0.0729 | |
| SRP193095 | SDC3 | 9672 | RNAseq | 1.3298 | 0.0000 | |
| SRP219564 | SDC3 | 9672 | RNAseq | -0.0099 | 0.9902 | |
| TCGA | SDC3 | 9672 | RNAseq | -0.1502 | 0.0614 |
Upregulated datasets: 3; Downregulated datasets: 1.
Survival by SDC3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SDC3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SDC3 | 9672 | 0 | 6 | 24 | |
| GSE20123 | SDC3 | 9672 | 0 | 5 | 25 | |
| GSE43470 | SDC3 | 9672 | 3 | 6 | 34 | |
| GSE46452 | SDC3 | 9672 | 5 | 1 | 53 | |
| GSE47630 | SDC3 | 9672 | 8 | 3 | 29 | |
| GSE54993 | SDC3 | 9672 | 1 | 1 | 68 | |
| GSE54994 | SDC3 | 9672 | 10 | 3 | 40 | |
| GSE60625 | SDC3 | 9672 | 0 | 0 | 11 | |
| GSE74703 | SDC3 | 9672 | 2 | 4 | 30 | |
| GSE74704 | SDC3 | 9672 | 0 | 0 | 20 | |
| TCGA | SDC3 | 9672 | 12 | 19 | 65 |
Total number of gains: 41; Total number of losses: 48; Total Number of normals: 399.
Somatic mutations of SDC3:
Generating mutation plots.
Highly correlated genes for SDC3:
Showing top 20/930 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SDC3 | C1orf54 | 0.725818 | 6 | 0 | 6 |
| SDC3 | SYNC | 0.714588 | 5 | 0 | 4 |
| SDC3 | ALDH1B1 | 0.709219 | 4 | 0 | 4 |
| SDC3 | EPHB4 | 0.707411 | 4 | 0 | 4 |
| SDC3 | PLBD2 | 0.699919 | 3 | 0 | 3 |
| SDC3 | ZNF423 | 0.699218 | 6 | 0 | 6 |
| SDC3 | IRF9 | 0.696196 | 5 | 0 | 5 |
| SDC3 | EML1 | 0.696118 | 6 | 0 | 6 |
| SDC3 | ANXA6 | 0.688392 | 8 | 0 | 8 |
| SDC3 | ITGA7 | 0.683202 | 4 | 0 | 3 |
| SDC3 | CCDC149 | 0.678408 | 3 | 0 | 3 |
| SDC3 | HSP90AA1 | 0.678054 | 4 | 0 | 3 |
| SDC3 | MRGPRF | 0.677371 | 4 | 0 | 4 |
| SDC3 | SYT11 | 0.676263 | 7 | 0 | 7 |
| SDC3 | AGTR1 | 0.675148 | 5 | 0 | 4 |
| SDC3 | STX1A | 0.674765 | 5 | 0 | 4 |
| SDC3 | RBM12B | 0.67431 | 3 | 0 | 3 |
| SDC3 | OSR1 | 0.673794 | 3 | 0 | 3 |
| SDC3 | HMCN1 | 0.673327 | 5 | 0 | 5 |
| SDC3 | LTBP1 | 0.672894 | 10 | 0 | 10 |
For details and further investigation, click here
