| Full name: aldehyde dehydrogenase 3 family member B2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11q13.2 | ||
| Entrez ID: 222 | HGNC ID: HGNC:411 | Ensembl Gene: ENSG00000132746 | OMIM ID: 601917 |
| Drug and gene relationship at DGIdb | |||
Expression of ALDH3B2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ALDH3B2 | 222 | 204942_s_at | -0.6787 | 0.6692 | |
| GSE20347 | ALDH3B2 | 222 | 204942_s_at | -1.9362 | 0.0000 | |
| GSE23400 | ALDH3B2 | 222 | 204942_s_at | -1.3854 | 0.0000 | |
| GSE26886 | ALDH3B2 | 222 | 204942_s_at | -2.8497 | 0.0000 | |
| GSE29001 | ALDH3B2 | 222 | 204942_s_at | -2.2013 | 0.0020 | |
| GSE38129 | ALDH3B2 | 222 | 204942_s_at | -1.0978 | 0.0621 | |
| GSE45670 | ALDH3B2 | 222 | 204942_s_at | 0.1137 | 0.7392 | |
| GSE53622 | ALDH3B2 | 222 | 70537 | -0.8391 | 0.0000 | |
| GSE53624 | ALDH3B2 | 222 | 70537 | -0.9126 | 0.0000 | |
| GSE63941 | ALDH3B2 | 222 | 204942_s_at | 1.3914 | 0.1381 | |
| GSE77861 | ALDH3B2 | 222 | 204942_s_at | -0.7942 | 0.1470 | |
| GSE97050 | ALDH3B2 | 222 | A_23_P24311 | 0.3156 | 0.7060 | |
| SRP007169 | ALDH3B2 | 222 | RNAseq | -3.3510 | 0.0000 | |
| SRP008496 | ALDH3B2 | 222 | RNAseq | -2.6069 | 0.0000 | |
| SRP064894 | ALDH3B2 | 222 | RNAseq | -1.8827 | 0.0003 | |
| SRP133303 | ALDH3B2 | 222 | RNAseq | -1.9395 | 0.0000 | |
| SRP159526 | ALDH3B2 | 222 | RNAseq | -2.1137 | 0.0025 | |
| SRP219564 | ALDH3B2 | 222 | RNAseq | -1.9734 | 0.1672 | |
| TCGA | ALDH3B2 | 222 | RNAseq | 1.4578 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 9.
Survival by ALDH3B2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ALDH3B2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ALDH3B2 | 222 | 10 | 3 | 17 | |
| GSE20123 | ALDH3B2 | 222 | 10 | 3 | 17 | |
| GSE43470 | ALDH3B2 | 222 | 5 | 2 | 36 | |
| GSE46452 | ALDH3B2 | 222 | 14 | 3 | 42 | |
| GSE47630 | ALDH3B2 | 222 | 8 | 5 | 27 | |
| GSE54993 | ALDH3B2 | 222 | 3 | 1 | 66 | |
| GSE54994 | ALDH3B2 | 222 | 13 | 4 | 36 | |
| GSE60625 | ALDH3B2 | 222 | 0 | 3 | 8 | |
| GSE74703 | ALDH3B2 | 222 | 4 | 1 | 31 | |
| GSE74704 | ALDH3B2 | 222 | 8 | 1 | 11 | |
| TCGA | ALDH3B2 | 222 | 36 | 9 | 51 |
Total number of gains: 111; Total number of losses: 35; Total Number of normals: 342.
Somatic mutations of ALDH3B2:
Generating mutation plots.
Highly correlated genes for ALDH3B2:
Showing top 20/1277 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ALDH3B2 | CYP4X1 | 0.788062 | 3 | 0 | 3 |
| ALDH3B2 | LYPD3 | 0.749272 | 11 | 0 | 11 |
| ALDH3B2 | PGLYRP3 | 0.733553 | 3 | 0 | 3 |
| ALDH3B2 | RBM20 | 0.729764 | 3 | 0 | 3 |
| ALDH3B2 | SLC39A2 | 0.725135 | 12 | 0 | 11 |
| ALDH3B2 | CES2 | 0.724028 | 8 | 0 | 8 |
| ALDH3B2 | CAPN14 | 0.721814 | 5 | 0 | 5 |
| ALDH3B2 | DDI2 | 0.718575 | 3 | 0 | 3 |
| ALDH3B2 | GLTP | 0.715772 | 10 | 0 | 8 |
| ALDH3B2 | TGM1 | 0.715047 | 12 | 0 | 11 |
| ALDH3B2 | SLURP1 | 0.713463 | 10 | 0 | 9 |
| ALDH3B2 | C10orf99 | 0.708137 | 6 | 0 | 6 |
| ALDH3B2 | KRTAP19-7 | 0.707061 | 3 | 0 | 3 |
| ALDH3B2 | SULT2B1 | 0.705994 | 10 | 0 | 9 |
| ALDH3B2 | TMEM161B | 0.704336 | 3 | 0 | 3 |
| ALDH3B2 | SH3PXD2A-AS1 | 0.702805 | 4 | 0 | 4 |
| ALDH3B2 | KLK13 | 0.701247 | 11 | 0 | 9 |
| ALDH3B2 | TOM1 | 0.698727 | 12 | 0 | 12 |
| ALDH3B2 | ZNF185 | 0.69686 | 11 | 0 | 10 |
| ALDH3B2 | CST6 | 0.696035 | 12 | 0 | 11 |
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