| Full name: LY6/PLAUR domain containing 3 | Alias Symbol: C4.4A | ||
| Type: protein-coding gene | Cytoband: 19q13.31 | ||
| Entrez ID: 27076 | HGNC ID: HGNC:24880 | Ensembl Gene: ENSG00000124466 | OMIM ID: 609484 |
| Drug and gene relationship at DGIdb | |||
Expression of LYPD3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LYPD3 | 27076 | 204952_at | -1.6101 | 0.1330 | |
| GSE20347 | LYPD3 | 27076 | 204952_at | -2.2866 | 0.0000 | |
| GSE23400 | LYPD3 | 27076 | 204952_at | -1.4942 | 0.0000 | |
| GSE26886 | LYPD3 | 27076 | 204952_at | -2.6612 | 0.0000 | |
| GSE29001 | LYPD3 | 27076 | 204952_at | -1.9267 | 0.0003 | |
| GSE38129 | LYPD3 | 27076 | 204952_at | -1.2125 | 0.0566 | |
| GSE45670 | LYPD3 | 27076 | 204952_at | -0.4299 | 0.1320 | |
| GSE53622 | LYPD3 | 27076 | 121 | -1.5187 | 0.0001 | |
| GSE53624 | LYPD3 | 27076 | 121 | -2.1479 | 0.0000 | |
| GSE63941 | LYPD3 | 27076 | 204952_at | 1.0175 | 0.1900 | |
| GSE77861 | LYPD3 | 27076 | 204952_at | -0.8219 | 0.0138 | |
| GSE97050 | LYPD3 | 27076 | A_24_P48495 | 0.1206 | 0.9472 | |
| SRP007169 | LYPD3 | 27076 | RNAseq | -3.5711 | 0.0000 | |
| SRP008496 | LYPD3 | 27076 | RNAseq | -3.6352 | 0.0000 | |
| SRP064894 | LYPD3 | 27076 | RNAseq | -2.3113 | 0.0000 | |
| SRP133303 | LYPD3 | 27076 | RNAseq | -2.5157 | 0.0000 | |
| SRP159526 | LYPD3 | 27076 | RNAseq | -2.6724 | 0.0008 | |
| SRP219564 | LYPD3 | 27076 | RNAseq | -2.3055 | 0.0543 | |
| TCGA | LYPD3 | 27076 | RNAseq | 1.0280 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 11.
Survival by LYPD3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LYPD3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LYPD3 | 27076 | 6 | 5 | 19 | |
| GSE20123 | LYPD3 | 27076 | 5 | 4 | 21 | |
| GSE43470 | LYPD3 | 27076 | 4 | 11 | 28 | |
| GSE46452 | LYPD3 | 27076 | 45 | 1 | 13 | |
| GSE47630 | LYPD3 | 27076 | 8 | 6 | 26 | |
| GSE54993 | LYPD3 | 27076 | 17 | 4 | 49 | |
| GSE54994 | LYPD3 | 27076 | 6 | 12 | 35 | |
| GSE60625 | LYPD3 | 27076 | 9 | 0 | 2 | |
| GSE74703 | LYPD3 | 27076 | 4 | 7 | 25 | |
| GSE74704 | LYPD3 | 27076 | 4 | 2 | 14 | |
| TCGA | LYPD3 | 27076 | 14 | 15 | 67 |
Total number of gains: 122; Total number of losses: 67; Total Number of normals: 299.
Somatic mutations of LYPD3:
Generating mutation plots.
Highly correlated genes for LYPD3:
Showing top 20/1412 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LYPD3 | TMEM79 | 0.856232 | 8 | 0 | 8 |
| LYPD3 | CYSRT1 | 0.849685 | 6 | 0 | 6 |
| LYPD3 | TGM1 | 0.841662 | 12 | 0 | 12 |
| LYPD3 | CNFN | 0.839138 | 8 | 0 | 8 |
| LYPD3 | TMEM40 | 0.823794 | 13 | 0 | 13 |
| LYPD3 | SERPINB1 | 0.821341 | 12 | 0 | 12 |
| LYPD3 | SBSN | 0.819682 | 8 | 0 | 8 |
| LYPD3 | CLIC3 | 0.818893 | 10 | 0 | 10 |
| LYPD3 | CWH43 | 0.811741 | 10 | 0 | 10 |
| LYPD3 | VSIG10L | 0.809577 | 7 | 0 | 7 |
| LYPD3 | CSTB | 0.80742 | 13 | 0 | 12 |
| LYPD3 | ZNF185 | 0.803427 | 13 | 0 | 12 |
| LYPD3 | ZNF750 | 0.799953 | 12 | 0 | 11 |
| LYPD3 | S100A14 | 0.799898 | 13 | 0 | 12 |
| LYPD3 | SULT2B1 | 0.799277 | 11 | 0 | 10 |
| LYPD3 | EVPL | 0.798233 | 13 | 0 | 13 |
| LYPD3 | MALL | 0.797958 | 13 | 0 | 12 |
| LYPD3 | TMEM154 | 0.797278 | 8 | 0 | 8 |
| LYPD3 | RHCG | 0.79644 | 13 | 0 | 12 |
| LYPD3 | ANXA1 | 0.794731 | 12 | 0 | 12 |
For details and further investigation, click here
