| Full name: chromosome 10 open reading frame 99 | Alias Symbol: UNQ1833|RLLV1833|FLJ21763|CSBF|AP-57 | ||
| Type: protein-coding gene | Cytoband: 10q23.1 | ||
| Entrez ID: 387695 | HGNC ID: HGNC:31428 | Ensembl Gene: ENSG00000188373 | OMIM ID: 617775 |
| Drug and gene relationship at DGIdb | |||
Expression of C10orf99:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C10orf99 | 387695 | 227736_at | -0.8924 | 0.6396 | |
| GSE26886 | C10orf99 | 387695 | 227736_at | -4.3938 | 0.0000 | |
| GSE45670 | C10orf99 | 387695 | 227736_at | 0.7970 | 0.0528 | |
| GSE53622 | C10orf99 | 387695 | 50480 | -1.7453 | 0.0000 | |
| GSE53624 | C10orf99 | 387695 | 50480 | -2.1724 | 0.0000 | |
| GSE63941 | C10orf99 | 387695 | 227735_s_at | 0.4154 | 0.2577 | |
| GSE77861 | C10orf99 | 387695 | 227735_s_at | -1.5118 | 0.1518 | |
| GSE97050 | C10orf99 | 387695 | A_33_P3392405 | -0.3208 | 0.6275 | |
| SRP007169 | C10orf99 | 387695 | RNAseq | -4.2627 | 0.0000 | |
| SRP008496 | C10orf99 | 387695 | RNAseq | -3.0678 | 0.0000 | |
| SRP064894 | C10orf99 | 387695 | RNAseq | -1.6140 | 0.0399 | |
| SRP133303 | C10orf99 | 387695 | RNAseq | -2.1820 | 0.0005 | |
| SRP159526 | C10orf99 | 387695 | RNAseq | -2.0163 | 0.0770 | |
| SRP219564 | C10orf99 | 387695 | RNAseq | -1.3194 | 0.3720 | |
| TCGA | C10orf99 | 387695 | RNAseq | 1.2433 | 0.0085 |
Upregulated datasets: 1; Downregulated datasets: 7.
Survival by C10orf99 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C10orf99:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C10orf99 | 387695 | 1 | 6 | 23 | |
| GSE20123 | C10orf99 | 387695 | 1 | 5 | 24 | |
| GSE43470 | C10orf99 | 387695 | 1 | 6 | 36 | |
| GSE46452 | C10orf99 | 387695 | 0 | 11 | 48 | |
| GSE47630 | C10orf99 | 387695 | 2 | 14 | 24 | |
| GSE54993 | C10orf99 | 387695 | 7 | 0 | 63 | |
| GSE54994 | C10orf99 | 387695 | 1 | 12 | 40 | |
| GSE60625 | C10orf99 | 387695 | 0 | 0 | 11 | |
| GSE74703 | C10orf99 | 387695 | 1 | 4 | 31 | |
| GSE74704 | C10orf99 | 387695 | 0 | 3 | 17 | |
| TCGA | C10orf99 | 387695 | 9 | 25 | 62 |
Total number of gains: 23; Total number of losses: 86; Total Number of normals: 379.
Somatic mutations of C10orf99:
Generating mutation plots.
Highly correlated genes for C10orf99:
Showing top 20/790 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C10orf99 | GRHL3 | 0.831253 | 6 | 0 | 6 |
| C10orf99 | CNFN | 0.802645 | 7 | 0 | 7 |
| C10orf99 | EPHX3 | 0.795902 | 5 | 0 | 5 |
| C10orf99 | SPRR2F | 0.795829 | 4 | 0 | 4 |
| C10orf99 | SPRR2A | 0.792787 | 4 | 0 | 4 |
| C10orf99 | SPRR2E | 0.791541 | 4 | 0 | 4 |
| C10orf99 | SPRR2D | 0.79008 | 4 | 0 | 4 |
| C10orf99 | LYPD3 | 0.7752 | 7 | 0 | 7 |
| C10orf99 | KRT13 | 0.774928 | 6 | 0 | 6 |
| C10orf99 | IVL | 0.768138 | 7 | 0 | 7 |
| C10orf99 | KLK11 | 0.766963 | 8 | 0 | 7 |
| C10orf99 | CYSRT1 | 0.765365 | 5 | 0 | 5 |
| C10orf99 | KRT83 | 0.762841 | 3 | 0 | 3 |
| C10orf99 | RHCG | 0.758406 | 7 | 0 | 7 |
| C10orf99 | ZNF185 | 0.753695 | 7 | 0 | 7 |
| C10orf99 | ZNF750 | 0.750722 | 7 | 0 | 6 |
| C10orf99 | TMEM40 | 0.748676 | 7 | 0 | 7 |
| C10orf99 | VSIG10L | 0.747052 | 6 | 0 | 6 |
| C10orf99 | NCCRP1 | 0.746546 | 4 | 0 | 4 |
| C10orf99 | SERPINB1 | 0.744481 | 7 | 0 | 7 |
For details and further investigation, click here
