| Full name: kallikrein related peptidase 13 | Alias Symbol: KLK-L4 | ||
| Type: protein-coding gene | Cytoband: 19q13.41 | ||
| Entrez ID: 26085 | HGNC ID: HGNC:6361 | Ensembl Gene: ENSG00000167759 | OMIM ID: 605505 |
| Drug and gene relationship at DGIdb | |||
Expression of KLK13:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KLK13 | 26085 | 205783_at | -3.7389 | 0.0553 | |
| GSE20347 | KLK13 | 26085 | 205783_at | -4.2264 | 0.0000 | |
| GSE23400 | KLK13 | 26085 | 205783_at | -3.5150 | 0.0000 | |
| GSE26886 | KLK13 | 26085 | 205783_at | -5.5914 | 0.0000 | |
| GSE29001 | KLK13 | 26085 | 205783_at | -4.2794 | 0.0000 | |
| GSE38129 | KLK13 | 26085 | 205783_at | -3.2813 | 0.0000 | |
| GSE45670 | KLK13 | 26085 | 205783_at | -1.1780 | 0.0332 | |
| GSE53622 | KLK13 | 26085 | 155333 | -3.3154 | 0.0000 | |
| GSE53624 | KLK13 | 26085 | 21903 | -3.7641 | 0.0000 | |
| GSE63941 | KLK13 | 26085 | 205783_at | 0.4396 | 0.7068 | |
| GSE77861 | KLK13 | 26085 | 205783_at | -3.3206 | 0.0153 | |
| GSE97050 | KLK13 | 26085 | A_24_P333697 | -0.8118 | 0.4985 | |
| SRP007169 | KLK13 | 26085 | RNAseq | -6.0629 | 0.0002 | |
| SRP008496 | KLK13 | 26085 | RNAseq | -6.3952 | 0.0000 | |
| SRP064894 | KLK13 | 26085 | RNAseq | -4.8062 | 0.0000 | |
| SRP133303 | KLK13 | 26085 | RNAseq | -4.1013 | 0.0000 | |
| SRP159526 | KLK13 | 26085 | RNAseq | -5.6122 | 0.0000 | |
| SRP219564 | KLK13 | 26085 | RNAseq | -4.3659 | 0.0010 | |
| TCGA | KLK13 | 26085 | RNAseq | 0.0784 | 0.8587 |
Upregulated datasets: 0; Downregulated datasets: 15.
Survival by KLK13 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KLK13:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KLK13 | 26085 | 3 | 4 | 23 | |
| GSE20123 | KLK13 | 26085 | 3 | 3 | 24 | |
| GSE43470 | KLK13 | 26085 | 4 | 11 | 28 | |
| GSE46452 | KLK13 | 26085 | 45 | 1 | 13 | |
| GSE47630 | KLK13 | 26085 | 9 | 6 | 25 | |
| GSE54993 | KLK13 | 26085 | 17 | 4 | 49 | |
| GSE54994 | KLK13 | 26085 | 4 | 14 | 35 | |
| GSE60625 | KLK13 | 26085 | 9 | 0 | 2 | |
| GSE74703 | KLK13 | 26085 | 4 | 7 | 25 | |
| GSE74704 | KLK13 | 26085 | 3 | 1 | 16 | |
| TCGA | KLK13 | 26085 | 15 | 19 | 62 |
Total number of gains: 116; Total number of losses: 70; Total Number of normals: 302.
Somatic mutations of KLK13:
Generating mutation plots.
Highly correlated genes for KLK13:
Showing top 20/1464 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KLK13 | CYSRT1 | 0.918374 | 6 | 0 | 6 |
| KLK13 | SCEL | 0.906287 | 12 | 0 | 12 |
| KLK13 | SPINK5 | 0.897665 | 12 | 0 | 12 |
| KLK13 | PRSS27 | 0.894469 | 8 | 0 | 8 |
| KLK13 | TMPRSS11E | 0.889898 | 11 | 0 | 11 |
| KLK13 | VSIG10L | 0.889479 | 7 | 0 | 7 |
| KLK13 | CNFN | 0.883762 | 8 | 0 | 8 |
| KLK13 | CLIC3 | 0.878778 | 10 | 0 | 10 |
| KLK13 | NCCRP1 | 0.878699 | 4 | 0 | 4 |
| KLK13 | TGM3 | 0.878032 | 12 | 0 | 12 |
| KLK13 | CRNN | 0.876249 | 12 | 0 | 12 |
| KLK13 | PPL | 0.875303 | 12 | 0 | 12 |
| KLK13 | KLK11 | 0.873104 | 13 | 0 | 13 |
| KLK13 | SULT2B1 | 0.870662 | 10 | 0 | 10 |
| KLK13 | ECM1 | 0.862342 | 12 | 0 | 12 |
| KLK13 | TGM1 | 0.860983 | 12 | 0 | 12 |
| KLK13 | SLURP1 | 0.8588 | 13 | 0 | 12 |
| KLK13 | SLC16A6 | 0.856189 | 10 | 0 | 10 |
| KLK13 | PRSS3 | 0.852553 | 12 | 0 | 12 |
| KLK13 | GDPD3 | 0.852213 | 12 | 0 | 11 |
For details and further investigation, click here
